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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of proteasomal ubiquitin-dependent protein catabolic process
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Accession:GO:0032435 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
Synonyms:exact_synonym: down regulation of proteasomal ubiquitin-dependent protein catabolic process;   downregulation of proteasomal ubiquitin-dependent protein catabolic process
 narrow_synonym: inhibition of proteasomal ubiquitin-dependent protein catabolic process


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negative regulation of proteasomal ubiquitin-dependent protein catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag5 BAG cochaperone 5 involved_in ISO (PMID:24475098) RGD PMID:24475098 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970 		JBrowse link
G Bag6 BAG cochaperone 6 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:3808636|PMID:18678708)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:18678708 GO_REF:0000024 GO_REF:0000107 MGI:3808636 NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657 		JBrowse link
G Camlg calcium modulating ligand involved_in ISO UniProtKB:Q9H9V4 (PMID:20553626) RGD PMID:20553626 NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552 		JBrowse link
G Ccar2 cell cycle and apoptosis regulator 2 involved_in ISO (PMID:23398316) RGD PMID:23398316 NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636 		JBrowse link
G Clec16a C-type lectin domain containing 16A acts_upstream_of_or_within ISO MGI:5648633 (PMID:24949970) RGD PMID:24949970 NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 involved_in ISO UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292) RGD PMID:28031292 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 involved_in ISO UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292) RGD PMID:28031292 NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080 		JBrowse link
G Csnk2b casein kinase 2 beta involved_in ISO (PMID:28031292) RGD PMID:28031292 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133 		JBrowse link
G Ddrgk1 DDRGK domain containing 1 involved_in ISO (PMID:28263186) RGD PMID:28263186 NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H involved_in ISO
IEA		 (PMID:32269044)
GO_REF:0000107		 RGD
Ensembl		 PMID:32269044 GO_REF:0000107 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G ENSRNOG00000069696 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 Ensembl chr 2:11,225,135...11,226,004 JBrowse link
G Fhit fragile histidine triad diadenosine triphosphatase involved_in ISO
ISS
IEA
IBA		 (PMID:15313915)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033		 RGD
UniProt
Ensembl
TreeGrafter
GO_Central		 PMID:15313915 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340 		JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 involved_in ISO
IEA		 (MGI:3807767|PMID:11546783)
GO_REF:0000107		 RGD
Ensembl		 PMID:11546783 GO_REF:0000107 MGI:3807767 NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997 		JBrowse link
G Hfe homeostatic iron regulator involved_in ISO (PMID:24904118)
GO:0010628 (MGI:5603002|PMID:24904118)		 RGD PMID:24904118 MGI:5603002 NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24613385)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24613385 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Klhl40 kelch-like family member 40 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:24960163)		 GO_Central
RGD		 PMID:24960163 GO_REF:0000033 NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800 		JBrowse link
G Map1a microtubule-associated protein 1A involved_in ISO (MGI:5703671|PMID:26609151) RGD PMID:26609151 MGI:5703671 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Mtm1 myotubularin 1 acts_upstream_of_or_within ISO MGI:2450997 (PMID:23695157) RGD PMID:23695157 NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860 		JBrowse link
G N4bp1 Nedd4 binding protein 1 involved_in ISO
IBA		 (MGI:3829128|PMID:17592138)
GO_REF:0000033		 RGD
GO_Central		 PMID:17592138 GO_REF:0000033 MGI:3829128 NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor involved_in ISO (PMID:22522597) RGD PMID:22522597 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:26678539)		 Ensembl
RGD		 PMID:26678539 GO_REF:0000107 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146 		JBrowse link
G Park7 Parkinsonism associated deglycase involved_in ISO
IEA		 (PMID:17015834)
GO_REF:0000107		 RGD
Ensembl		 PMID:17015834 GO_REF:0000107 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pbk PDZ binding kinase acts_upstream_of_or_within ISO MGI:5293435 (PMID:21715333) RGD PMID:21715333 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Phf20l1 PHD finger protein 20-like 1 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:24492612)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:24492612 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526 		JBrowse link
G Rpl11 ribosomal protein L11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5897550|PMID:21804542)		 UniProt
RGD		 PMID:21804542 GO_REF:0000024 MGI:5897550 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpp21 ribonuclease P/MRP subunit p21 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106 		JBrowse link
G Rybp RING1 and YY1 binding protein involved_in ISO (PMID:27060496) RGD PMID:27060496 NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316 		JBrowse link
G Senp1 SUMO specific peptidase 1 acts_upstream_of_or_within ISO MGI:3818522 (PMID:17981124) RGD PMID:17981124 NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16611981)		 Ensembl
RGD		 PMID:16611981 GO_REF:0000107 NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 acts_upstream_of_or_within ISO (PMID:22285184) RGD PMID:22285184 NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 involved_in ISO
IEA		 (PMID:11278372)
GO_REF:0000107		 RGD
Ensembl		 PMID:11278372 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Tlk2 tousled-like kinase 2 involved_in ISO (PMID:20016786) RGD PMID:20016786 NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561 		JBrowse link
G Trim39 tripartite motif-containing 39 involved_in ISO
ISS
IEA
IBA		 (PMID:23213251)
GO_REF:0000024
GO_REF:0000107
GO_REF:0000118
GO_REF:0000033		 RGD
UniProt
Ensembl
TreeGrafter
GO_Central		 PMID:23213251 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117 		JBrowse link
G Ttc36 tetratricopeptide repeat domain 36 acts_upstream_of_or_within ISO MGI:5588394 (PMID:31537781) RGD PMID:31537781 NCBI chr 8:45,112,737...45,116,345 JBrowse link
G Ubxn1 UBX domain protein 1 involved_in ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:20351172)
GO_REF:0000118
GO_REF:0000033		 UniProt
RGD
TreeGrafter
GO_Central		 PMID:20351172 GO_REF:0000024 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 involved_in ISO (PMID:23770237) RGD PMID:23770237 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Usp26 ubiquitin specific peptidase 26 involved_in ISO (PMID:28839133)
(MGI:5926846|PMID:28839133)		 RGD PMID:28839133 MGI:5926846 NCBI chr  X:131,317,200...131,363,964
Ensembl chr  X:131,319,194...131,363,970 		JBrowse link
G Usp38 ubiquitin specific peptidase 38 involved_in ISO (PMID:34102342) RGD PMID:34102342 NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 involved_in ISO
IEA		 (PMID:26678539)
GO_REF:0000107		 RGD
Ensembl		 PMID:26678539 GO_REF:0000107 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked involved_in ISO (PMID:33378666) RGD PMID:33378666 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711 		JBrowse link
G Wac WW domain containing adaptor with coiled-coil involved_in ISO (PMID:22354037) RGD PMID:22354037 NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301 		JBrowse link
negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pabpn1l PABPN1 like acts_upstream_of_or_within ISO (PMID:32558204) RGD PMID:32558204 NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366 		JBrowse link
G Styx serine/threonine/tyrosine interacting protein involved_in ISO
IBA		 (PMID:28007894)
GO_REF:0000033		 RGD
GO_Central		 PMID:28007894 GO_REF:0000033 NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      catabolic process 2859
        negative regulation of catabolic process 373
          negative regulation of ubiquitin-dependent protein catabolic process 62
            negative regulation of proteasomal ubiquitin-dependent protein catabolic process 43
              negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process 2
              negative regulation of anaphase-promoting complex-dependent catabolic process 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    metabolic process 11835
      organic substance metabolic process 11328
        macromolecule metabolic process 9578
          protein metabolic process 4746
            proteolysis 1615
              proteolysis involved in protein catabolic process 862
                modification-dependent protein catabolic process 683
                  ubiquitin-dependent protein catabolic process 664
                    proteasome-mediated ubiquitin-dependent protein catabolic process 455
                      regulation of proteasomal ubiquitin-dependent protein catabolic process 138
                        negative regulation of proteasomal ubiquitin-dependent protein catabolic process 43
                          negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process 2
                          negative regulation of anaphase-promoting complex-dependent catabolic process 0
paths to the root