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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ion transmembrane transporter activity
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Accession:GO:0032413 term browser browse the term
Definition:Any process that stops or reduces the activity of an ion transporter.
Synonyms:exact_synonym: down regulation of ion transporter activity;   downregulation of ion transporter activity;   negative regulation of ion transporter activity
 narrow_synonym: inhibition of ion transporter activity



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negative regulation of AMPA receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grip1 glutamate receptor interacting protein 1 IMP RGD PMID:12597860 RGD:152995391 NCBI chr 7:54,934,856...55,592,274
Ensembl chr 7:54,934,250...55,592,273
JBrowse link
negative regulation of anion channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Grk6 G protein-coupled receptor kinase 6 IMP Cl-/HCO3- exchange activity RGD PMID:17170521 RGD:5684927 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644
JBrowse link
negative regulation of calcium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp2ca protein phosphatase 2 catalytic subunit alpha IMP RGD PMID:15728831 RGD:8554004 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862
JBrowse link
negative regulation of cation channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 IDA RGD PMID:20624795 RGD:6849299 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Fgf12 fibroblast growth factor 12 IDA RGD PMID:12401812 RGD:6484231 NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607
JBrowse link
negative regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 IDA
IMP
RGD PMID:8183366 PMID:8799886 RGD:61642, RGD:9743956 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534
JBrowse link
G Mtnr1b melatonin receptor 1B IDA RGD PMID:14962062 RGD:9588668 NCBI chr 8:12,638,219...12,652,737
Ensembl chr 8:12,638,219...12,652,737
JBrowse link
negative regulation of inward rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snx27 sorting nexin 27 IDA RGD PMID:21422294 RGD:8554349 NCBI chr 2:182,135,904...182,218,906
Ensembl chr 2:182,135,905...182,218,906
JBrowse link
negative regulation of NMDA glutamate receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Park7 Parkinsonism associated deglycase IMP RGD PMID:20698836 RGD:13463453 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
negative regulation of P-type sodium:potassium-exchanging transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fxyd2 FXYD domain-containing ion transport regulator 2 IMP RGD PMID:15280368 RGD:1598989 NCBI chr 8:45,712,901...45,720,032
Ensembl chr 8:45,712,903...45,720,203
JBrowse link
negative regulation of potassium ion transmembrane transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pten phosphatase and tensin homolog IMP RGD PMID:24103758 RGD:12802338 NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
negative regulation of sodium:proton antiporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd3 dopamine receptor D3 IMP RGD PMID:15265811 RGD:1625070 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
negative regulation of voltage-gated calcium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cabp1 calcium binding protein 1 IDA RGD PMID:17960496 RGD:7207144 NCBI chr12:41,385,234...41,448,930
Ensembl chr12:41,378,897...41,448,927
JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 IDA RGD PMID:15024042 RGD:13514097 NCBI chr 7:129,784,799...129,797,074
Ensembl chr 7:129,783,674...129,797,074
JBrowse link
G Cbarp CACN subunit beta associated regulatory protein IMP RGD PMID:24751537 RGD:10047103 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 IMP RGD PMID:26584289 RGD:155804278 NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
JBrowse link
G Oprl1 opioid related nociceptin receptor 1 IMP RGD PMID:15937148 RGD:9835002 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920
JBrowse link
negative regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187 PMID:21943416 PMID:21943417 RGD:7243967, RGD:7242916, RGD:12910700 NCBI chr11:31,580,951...31,594,116
Ensembl chr11:31,580,742...31,593,901
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:19219384 PMID:21943416 PMID:14679187 RGD:7243947, RGD:7242916, RGD:7243967 NCBI chr11:31,517,176...31,530,026
Ensembl chr11:31,295,614...31,530,043
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA RGD PMID:14679187 RGD:7243967 NCBI chr 1:154,523,903...154,530,865
Ensembl chr 1:154,523,830...154,532,020
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    negative regulation of biological process 5676
      negative regulation of transport 544
        negative regulation of transporter activity 21
          negative regulation of ion transmembrane transporter activity 20
            negative regulation of AMPA receptor activity 1
            negative regulation of NMDA glutamate receptor activity 1
            negative regulation of anion channel activity + 1
            negative regulation of calcium ion transmembrane transporter activity + 6
            negative regulation of cation channel activity + 13
            negative regulation of cyclic nucleotide-gated ion channel activity 0
            negative regulation of cytochrome-c oxidase activity 0
            negative regulation of iron ion transmembrane transporter activity 0
            negative regulation of light-activated channel activity 0
            negative regulation of potassium ion transmembrane transporter activity + 8
            negative regulation of sodium ion transmembrane transporter activity + 2
Path 2
Term Annotations click to browse term
  biological_process 19574
    localization 5545
      establishment of localization 4868
        transport 4676
          regulation of transport 1901
            regulation of transmembrane transport 432
              regulation of transmembrane transporter activity 70
                regulation of monoatomic ion transmembrane transporter activity 69
                  negative regulation of ion transmembrane transporter activity 20
                    negative regulation of AMPA receptor activity 1
                    negative regulation of NMDA glutamate receptor activity 1
                    negative regulation of anion channel activity + 1
                    negative regulation of calcium ion transmembrane transporter activity + 6
                    negative regulation of cation channel activity + 13
                    negative regulation of cyclic nucleotide-gated ion channel activity 0
                    negative regulation of cytochrome-c oxidase activity 0
                    negative regulation of iron ion transmembrane transporter activity 0
                    negative regulation of light-activated channel activity 0
                    negative regulation of potassium ion transmembrane transporter activity + 8
                    negative regulation of sodium ion transmembrane transporter activity + 2
paths to the root