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ONTOLOGY REPORT - ANNOTATIONS


Term:MutLalpha complex
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Accession:GO:0032389 term browser browse the term
Definition:A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Synonyms:exact_synonym: MLH1/PMS2 complex;   MutL-alpha complex
 broad_synonym: MMR complex


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MutLalpha complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 ISO (MGI:3653556|PMID:16713580), (MGI:5315075|PMID:22164254) MGI PMID:16713580, PMID:22164254 MGI:3653556, MGI:5315075 NCBI chrNW_004936473:26,556,636...26,600,830 JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO (MGI:3653556|PMID:16713580) MGI PMID:16713580 MGI:3653556 NCBI chrNW_004936750:439,396...468,747 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 12106
    protein-containing complex 3865
      nuclear protein-containing complex 897
        MutLalpha complex 2
Path 2
Term Annotations click to browse term
  cellular_component 12106
    cellular anatomical entity 11960
      organelle 9372
        membrane-bounded organelle 8295
          intracellular membrane-bounded organelle 7685
            nucleus 5197
              nuclear protein-containing complex 897
                MutLalpha complex 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.