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ONTOLOGY REPORT - ANNOTATIONS


Term:MutLalpha complex
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Accession:GO:0032389 term browser browse the term
Definition:A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Synonyms:exact_synonym: MLH1/PMS2 complex;   MutL-alpha complex
 broad_synonym: MMR complex


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MutLalpha complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 IBA
IDA
(MGI:6201960|PMID:21873635)
(MGI:3653556|PMID:16713580), (MGI:5315075|PMID:22164254)
GO_Central
MGI
PMID:16713580, PMID:21873635, PMID:22164254 MGI:3653556, MGI:5315075, MGI:6201960 NCBI chr 9:111,228,228...111,271,786
Ensembl chr 9:111,228,228...111,271,791
JBrowse link
G Pms2 PMS1 homolog2, mismatch repair system component IDA
IBA
(MGI:3653556|PMID:16713580)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:16713580, PMID:21873635 MGI:3653556, MGI:6201960 NCBI chr 5:143,909,901...143,972,745
Ensembl chr 5:143,909,964...143,933,968
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 23184
    protein-containing complex 5493
      nuclear protein-containing complex 1202
        MutLalpha complex 2
Path 2
Term Annotations click to browse term
  cellular_component 23184
    cellular anatomical entity 19097
      organelle 12901
        membrane-bounded organelle 11539
          intracellular membrane-bounded organelle 10799
            nucleus 7172
              nuclear protein-containing complex 1202
                MutLalpha complex 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.