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ONTOLOGY REPORT - ANNOTATIONS


Term:MutLalpha complex
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Accession:GO:0032389 term browser browse the term
Definition:A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Synonyms:exact_synonym: MLH1/PMS2 complex;   MutL-alpha complex
 broad_synonym: MMR complex


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MutLalpha complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MLH1 mutL homolog 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:36,993,487...37,050,846
Ensembl chr 3:36,993,350...37,050,846
Ensembl chr 3:36,993,350...37,050,846
JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,106
JBrowse link
G PMS2P1 PMS1 homolog 2, mismatch repair system component pseudogene 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:100,320,640...100,336,307
Ensembl chr 7:100,319,222...100,336,307
Ensembl chr 7:100,319,222...100,336,307
JBrowse link
G PMS2P2 PMS1 homolog 2, mismatch repair system component pseudogene 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:75,343,937...75,358,997
Ensembl chr 7:75,344,015...75,359,550
JBrowse link
G PMS2P5 PMS1 homolog 2, mismatch repair system component pseudogene 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:74,890,768...74,921,138
Ensembl chr 7:74,894,116...74,897,835
JBrowse link
G PMS2P6 PMS1 homolog 2, mismatch repair system component pseudogene 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:73,093,644...73,096,950
Ensembl chr 7:73,093,657...73,105,389
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19335
    protein-containing complex 5896
      nuclear protein-containing complex 1295
        MutLalpha complex 6
Path 2
Term Annotations click to browse term
  cellular_component 19335
    cellular anatomical entity 19099
      organelle 14295
        membrane-bounded organelle 12927
          intracellular membrane-bounded organelle 11430
            nucleus 7649
              nuclear protein-containing complex 1295
                MutLalpha complex 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.