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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of intracellular cholesterol transport
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Accession:GO:0032384 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.
Synonyms:exact_synonym: down regulation of intracellular cholesterol transport;   downregulation of intracellular cholesterol transport
 narrow_synonym: inhibition of intracellular cholesterol transport


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negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004936522:6,271,339...6,300,202 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    negative regulation of biological process 4639
      negative regulation of transport 483
        negative regulation of intracellular transport 64
          negative regulation of intracellular lipid transport 2
            negative regulation of intracellular sterol transport 2
              negative regulation of intracellular cholesterol transport 2
                negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
Path 2
Term Annotations click to browse term
  biological_process 12001
    localization 4781
      establishment of localization 3430
        transport 3278
          organic substance transport 1722
            lipid transport 274
              regulation of lipid transport 136
                negative regulation of lipid transport 36
                  negative regulation of sterol transport 14
                    negative regulation of cholesterol transport 14
                      negative regulation of intracellular cholesterol transport 2
                        negative regulation of receptor-mediated endocytosis involved in cholesterol transport 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.