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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of sterol transport
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Accession:GO:0032372 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of sterol transport;   downregulation of sterol transport
 narrow_synonym: inhibition of sterol transport


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negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484
G APOE apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,365...112,330,046 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in ISO (MGI:4411947|PMID:19752193) UniProt PMID:19752193 MGI:4411947 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860 		JBrowse link
G LOC110259864 group 10 secretory phospholipase A2-like involved_in ISO (MGI:5051938|PMID:20844270) BHF-UCL PMID:20844270 MGI:5051938 NCBI chr 3:7,623,326...7,641,061
Ensembl chr 3:7,623,311...7,641,082 		JBrowse link
G MIR128-1 microRNA mir-128-1 involved_in
acts_upstream_of		 ISO (PMID:26501192)
(PMID:23990020)		 BHF-UCL PMID:23990020 PMID:26501192 NCBI chr15:16,273,557...16,273,638
Ensembl chr15:16,273,551...16,273,659 		JBrowse link
G MIR128-2 microRNA mir-128-2 acts_upstream_of
involved_in		 ISO (PMID:23990020)
(PMID:26501192)		 BHF-UCL PMID:23990020 PMID:26501192 NCBI chr13:21,038,445...21,038,524
Ensembl chr13:21,038,442...21,038,525 		JBrowse link
G MIR130B microRNA mir-130b involved_in ISO (PMID:26501192) BHF-UCL PMID:26501192 NCBI chr14:50,245,041...50,245,120
Ensembl chr14:50,245,041...50,245,120 		JBrowse link
G MIR144 microRNA mir-144 involved_in ISO (PMID:23519695)
(PMID:24733347)		 BHF-UCL
ARUK-UCL		 PMID:23519695 PMID:24733347 NCBI chr12:45,088,958...45,089,033
Ensembl chr12:45,088,959...45,089,035 		JBrowse link
G MIR148A microRNA mir-148a involved_in ISO (PMID:26437365), (PMID:26501192) BHF-UCL PMID:26437365 PMID:26501192 NCBI chr18:46,415,213...46,415,280
Ensembl chr18:46,415,202...46,415,281 		JBrowse link
G MIR19B-1 microRNA mir-19b-1 involved_in ISO (PMID:25084135)
(PMID:25765596)		 BHF-UCL PMID:25084135 PMID:25765596 NCBI chr11:60,735,238...60,735,317
Ensembl chr11:60,735,230...60,735,328 		JBrowse link
G MIR19B-2 microRNA mir-19b-2 involved_in ISO (PMID:25084135)
(PMID:25765596)		 BHF-UCL PMID:25084135 PMID:25765596 NCBI chr  X:110,113,855...110,113,934
Ensembl chr  X:110,113,855...110,113,934 		JBrowse link
G MIR206 microRNA mir-206 acts_upstream_of ISO (PMID:24603323) BHF-UCL PMID:24603323 NCBI chr 7:45,976,293...45,976,372
Ensembl chr 7:45,976,293...45,976,372 		JBrowse link
G MIR27A microRNA mir-27a involved_in ISO (PMID:24608080) ARUK-UCL PMID:24608080 NCBI chr 2:65,308,294...65,308,375
Ensembl chr 2:65,308,294...65,308,375 		JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:24608080), (PMID:26520906) ARUK-UCL PMID:24608080 PMID:26520906 NCBI chr10:27,079,963...27,080,042
Ensembl chr10:27,079,954...27,080,056 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,718...2,555,484 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:15358760) Ensembl
Ensembl
BHF-UCL		 PMID:15358760 GO_REF:0000107 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,487...6,784,672 		JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538 JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320 		JBrowse link
G APOC2 apolipoprotein C2 involved_in ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr 6:51,404,219...51,406,302 JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:96,616,304...96,656,893
Ensembl chr 3:96,616,246...96,656,893 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:96,596,975...96,616,224
Ensembl chr 3:96,594,778...96,616,229 		JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484
G MIR17 microRNA mir-17 involved_in ISO (PMID:23285084) ARUK-UCL PMID:23285084 NCBI chr11:60,734,656...60,734,732
Ensembl chr11:60,734,656...60,734,732 		JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:26520906) ARUK-UCL PMID:26520906 NCBI chr10:27,079,963...27,080,042
Ensembl chr10:27,079,954...27,080,056 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 6:157,388,370...157,409,620
Ensembl chr 6:157,388,372...157,409,604 		JBrowse link
negative regulation of reverse cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR144 microRNA mir-144 involved_in ISO (PMID:24733347) ARUK-UCL PMID:24733347 NCBI chr12:45,088,958...45,089,033
Ensembl chr12:45,088,959...45,089,035 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17278
    negative regulation of biological process 5651
      negative regulation of transport 574
        negative regulation of lipid transport 50
          negative regulation of sterol transport 24
            negative regulation of cholesterol transport + 24
            negative regulation of intracellular sterol transport + 4
            negative regulation of sterol import 0
Path 2
Term Annotations click to browse term
  biological_process 17278
    localization 5292
      establishment of localization 4655
        transport 4491
          organic substance transport 2397
            lipid transport 436
              sterol transport 133
                regulation of sterol transport 76
                  negative regulation of sterol transport 24
                    negative regulation of cholesterol transport + 24
                    negative regulation of intracellular sterol transport + 4
                    negative regulation of sterol import 0
paths to the root