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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of sterol transport
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Accession:GO:0032372 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of sterol transport;   downregulation of sterol transport
 narrow_synonym: inhibition of sterol transport


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negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL
ARUK-UCL		 PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915 		JBrowse link
G APOE apolipoprotein E involved_in IDA (PMID:12042316) Alzheimers_University_of_Toronto
Alzheimers_University_of_Toronto		 PMID:12042316 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766 		JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in ISO (MGI:4411947|PMID:19752193) UniProt PMID:19752193 MGI:4411947 NCBI chr  X:154,010,507...154,019,902
Ensembl chr  X:154,010,506...154,019,902 		JBrowse link
G MIR128-1 microRNA 128-1 acts_upstream_of
involved_in		 IDA (PMID:23990020)
(PMID:26501192)		 BHF-UCL PMID:23990020 PMID:26501192 NCBI chr 2:135,665,397...135,665,478
Ensembl chr 2:135,665,397...135,665,478 		JBrowse link
G MIR128-2 microRNA 128-2 acts_upstream_of
involved_in		 IDA (PMID:23990020)
(PMID:26501192)		 BHF-UCL PMID:23990020 PMID:26501192 NCBI chr 3:35,744,476...35,744,559
Ensembl chr 3:35,744,476...35,744,559 		JBrowse link
G MIR130B microRNA 130b involved_in IDA (PMID:26501192) BHF-UCL PMID:26501192 NCBI chr22:21,653,304...21,653,385
Ensembl chr22:21,653,304...21,653,385 		JBrowse link
G MIR144 microRNA 144 involved_in IGI
IDA		 (PMID:24733347)
(PMID:23519695)		 ARUK-UCL
BHF-UCL		 PMID:23519695 PMID:24733347 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618 		JBrowse link
G MIR148A microRNA 148a involved_in IDA (PMID:26437365), (PMID:26501192) BHF-UCL PMID:26437365 PMID:26501192 NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986 		JBrowse link
G MIR19B1 microRNA 19b-1 involved_in IDA
IMP		 (PMID:25084135)
(PMID:25765596)		 BHF-UCL PMID:25084135 PMID:25765596 NCBI chr13:91,351,192...91,351,278
Ensembl chr13:91,351,192...91,351,278 		JBrowse link
G MIR19B2 microRNA 19b-2 involved_in IDA
IMP		 (PMID:25084135)
(PMID:25765596)		 BHF-UCL PMID:25084135 PMID:25765596 NCBI chr  X:134,169,671...134,169,766
Ensembl chr  X:134,169,671...134,169,766 		JBrowse link
G MIR206 microRNA 206 acts_upstream_of IMP (PMID:24603323) BHF-UCL PMID:24603323 NCBI chr 6:52,144,349...52,144,434
Ensembl chr 6:52,144,349...52,144,434 		JBrowse link
G MIR26A1 microRNA 26a-1 involved_in ISS (PMID:22673513) BHF-UCL PMID:22673513 NCBI chr 3:37,969,404...37,969,480
Ensembl chr 3:37,969,404...37,969,480 		JBrowse link
G MIR26A2 microRNA 26a-2 involved_in ISS (PMID:22673513) BHF-UCL PMID:22673513 NCBI chr12:57,824,609...57,824,692
Ensembl chr12:57,824,609...57,824,692 		JBrowse link
G MIR27A microRNA 27a involved_in IDA (PMID:24608080) ARUK-UCL PMID:24608080 NCBI chr19:13,836,440...13,836,517
Ensembl chr19:13,836,440...13,836,517 		JBrowse link
G MIR27B microRNA 27b involved_in IDA (PMID:24608080), (PMID:26520906) ARUK-UCL PMID:24608080 PMID:26520906 NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541 		JBrowse link
G MIR301B microRNA 301b involved_in IDA (PMID:26501192) BHF-UCL PMID:26501192 NCBI chr22:21,652,981...21,653,058
Ensembl chr22:21,652,981...21,653,058 		JBrowse link
G MIR302A microRNA 302a involved_in IDA (PMID:25524771) BHF-UCL PMID:25524771 NCBI chr 4:112,648,183...112,648,251
Ensembl chr 4:112,648,183...112,648,251 		JBrowse link
G MIR33A microRNA 33a involved_in
acts_upstream_of		 IDA
IMP		 (PMID:20466885), (PMID:20566875)
(PMID:20466882)
(PMID:20855588)		 BHF-UCL PMID:20466882 PMID:20466885 PMID:20566875 PMID:20855588 NCBI chr22:41,900,944...41,901,012
Ensembl chr22:41,900,944...41,901,012 		JBrowse link
G MIR33B microRNA 33b involved_in IMP (PMID:24931346) BHF-UCL PMID:24931346 NCBI chr17:17,813,836...17,813,931
Ensembl chr17:17,813,836...17,813,931 		JBrowse link
G MIR613 microRNA 613 involved_in IMP (PMID:24751522) BHF-UCL PMID:24751522 NCBI chr12:12,764,649...12,764,743
Ensembl chr12:12,764,649...12,764,743 		JBrowse link
G MIR758 microRNA 758 involved_in IDA (PMID:21885853) BHF-UCL PMID:21885853 NCBI chr14:101,026,020...101,026,107
Ensembl chr14:101,026,020...101,026,107 		JBrowse link
G PLA2G10 phospholipase A2 group X involved_in ISS
IEA		 (PMID:20844270) BHF-UCL
BHF-UCL
Ensembl		 PMID:20844270 GO_REF:0000107 NCBI chr16:14,672,548...14,701,850
Ensembl chr16:14,672,548...14,694,308 		JBrowse link
G SHH sonic hedgehog signaling molecule involved_in ISS
IEA		 BHF-UCL
BHF-UCL
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463 		JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 acts_upstream_of IDA (PMID:15358760) BHF-UCL
BHF-UCL		 PMID:15358760 NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,079...41,907,307 		JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IDA (PMID:10764676) BHF-UCL
BHF-UCL		 PMID:10764676 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOC3 apolipoprotein C3 involved_in IMP (PMID:15778093) BHF-UCL
BHF-UCL		 PMID:15778093 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072 		JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IMP (PMID:8636092) BHF-UCL
BHF-UCL		 PMID:8636092 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631 		JBrowse link
G APOC1 apolipoprotein C1 involved_in IBA
IDA		 (PMID:21873635)
(PMID:10978346)		 GO_Central
BHF-UCL
GO_Central
BHF-UCL		 PMID:10978346 PMID:21873635 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349 		JBrowse link
G APOC2 apolipoprotein C2 involved_in IMP (PMID:15778093) BHF-UCL
BHF-UCL		 PMID:15778093 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,946,035...44,949,565 		JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in IC (PMID:16938301) BHF-UCL
BHF-UCL		 PMID:16938301 NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,331...102,617,302 		JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 involved_in IMP (PMID:11099417) BHF-UCL
BHF-UCL		 PMID:11099417 NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865 		JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 involved_in IMP (PMID:11099417) BHF-UCL
BHF-UCL		 PMID:11099417 NCBI chr 2:43,838,971...43,882,988
Ensembl chr 2:43,831,942...43,882,988 		JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL
ARUK-UCL		 PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915 		JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL
ARUK-UCL		 PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915 		JBrowse link
G MIR17 microRNA 17 involved_in IDA (PMID:23285084) ARUK-UCL PMID:23285084 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688 		JBrowse link
G MIR27B microRNA 27b involved_in IDA (PMID:26520906) ARUK-UCL PMID:26520906 NCBI chr 9:95,085,445...95,085,541
Ensembl chr 9:95,085,445...95,085,541 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22848640) BHF-UCL
BHF-UCL		 PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852 		JBrowse link
negative regulation of reverse cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR144 microRNA 144 involved_in IGI (PMID:24733347) ARUK-UCL PMID:24733347 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618 		JBrowse link
G MIR19B1 microRNA 19b-1 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr13:91,351,192...91,351,278
Ensembl chr13:91,351,192...91,351,278 		JBrowse link
G MIR19B2 microRNA 19b-2 involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr  X:134,169,671...134,169,766
Ensembl chr  X:134,169,671...134,169,766 		JBrowse link
G MIR33A microRNA 33a involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr22:41,900,944...41,901,012
Ensembl chr22:41,900,944...41,901,012 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19643
    negative regulation of biological process 6581
      negative regulation of transport 637
        negative regulation of lipid transport 61
          negative regulation of sterol transport 34
            negative regulation of cholesterol transport + 34
            negative regulation of intracellular sterol transport + 4
            negative regulation of sterol import 0
Path 2
Term Annotations click to browse term
  biological_process 19643
    localization 5902
      establishment of localization 5232
        transport 5071
          organic substance transport 2811
            lipid transport 484
              sterol transport 145
                regulation of sterol transport 87
                  negative regulation of sterol transport 34
                    negative regulation of cholesterol transport + 34
                    negative regulation of intracellular sterol transport + 4
                    negative regulation of sterol import 0
paths to the root