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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of sterol transport
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Accession:GO:0032372 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of sterol transport;   downregulation of sterol transport
 narrow_synonym: inhibition of sterol transport



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negative regulation of cholesterol efflux term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
G APOE apolipoprotein E involved_in ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G EGF epidermal growth factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 involved_in ISO (MGI:4411947|PMID:19752193) UniProt PMID:19752193 MGI:4411947 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576
JBrowse link
G MIR128-1 microRNA mir-128-1 acts_upstream_of
involved_in
ISO (PMID:23990020)
(PMID:26501192)
BHF-UCL PMID:23990020 PMID:26501192 NCBI chr19:38,435,956...38,436,011 JBrowse link
G MIR128-2 microRNA mir-128-2 acts_upstream_of
involved_in
ISO (PMID:23990020)
(PMID:26501192)
BHF-UCL PMID:23990020 PMID:26501192 NCBI chr23:5,826,463...5,826,520
Ensembl chr23:5,826,449...5,826,532
JBrowse link
G MIR144 microRNA mir-144 involved_in ISO (PMID:23519695)
(PMID:24733347)
BHF-UCL
ARUK-UCL
PMID:23519695 PMID:24733347 NCBI chr 9:43,031,035...43,031,094
Ensembl chr 9:43,031,035...43,031,094
JBrowse link
G MIR148A microRNA mir-148a involved_in ISO (PMID:26437365), (PMID:26501192) BHF-UCL PMID:26437365 PMID:26501192 NCBI chr14:39,301,847...39,301,906
Ensembl chr14:39,301,843...39,301,920
JBrowse link
G MIR19B-1 microRNA mir-19b-1 involved_in ISO (PMID:25765596)
(PMID:25084135)
BHF-UCL PMID:25084135 PMID:25765596 NCBI chr22:42,478,598...42,478,656 JBrowse link
G MIR19B-2 microRNA mir-19b-2 involved_in ISO (PMID:25765596)
(PMID:25084135)
BHF-UCL PMID:25084135 PMID:25765596 NCBI chr  X:104,895,962...104,896,025
Ensembl chr  X:104,895,962...104,896,025
JBrowse link
G MIR206 microRNA mir-206 acts_upstream_of ISO (PMID:24603323) BHF-UCL PMID:24603323 NCBI chr12:19,805,523...19,805,582
Ensembl chr12:19,805,523...19,805,582
JBrowse link
G MIR27A microRNA mir-27a involved_in ISO (PMID:24608080) ARUK-UCL PMID:24608080 NCBI chr20:48,620,556...48,620,615
Ensembl chr20:48,620,556...48,620,615
JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:24608080), (PMID:26520906) ARUK-UCL PMID:24608080 PMID:26520906 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191
JBrowse link
G MIR301B microRNA mir-301b involved_in ISO (PMID:26501192) BHF-UCL PMID:26501192 NCBI chr26:30,924,103...30,924,178
Ensembl chr26:30,924,103...30,924,178
JBrowse link
G MIR302A microRNA mir-302a involved_in ISO (PMID:25524771) BHF-UCL PMID:25524771 NCBI chr32:32,429,209...32,429,277
Ensembl chr32:32,429,209...32,429,277
JBrowse link
G MIR33A microRNA mir-33a acts_upstream_of
involved_in
ISO (PMID:20466882)
(PMID:20855588)
(PMID:20466885), (PMID:20566875)
BHF-UCL PMID:20466882 PMID:20466885 PMID:20566875 PMID:20855588 NCBI chr10:23,456,613...23,456,673
Ensembl chr10:23,456,613...23,456,673
JBrowse link
G MIR33B microRNA mir-33b involved_in ISO (PMID:24931346) BHF-UCL PMID:24931346 NCBI chr 5:41,685,165...41,685,258
Ensembl chr 5:41,685,165...41,685,258
JBrowse link
G PLA2G10 phospholipase A2 group X involved_in ISO (MGI:5051938|PMID:20844270) BHF-UCL PMID:20844270 MGI:5051938 NCBI chr 6:28,573,239...28,591,714
Ensembl chr 6:28,574,387...28,591,703
JBrowse link
G SHH sonic hedgehog signaling molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 involved_in
acts_upstream_of
IEA
ISO
(PMID:15358760) Ensembl
Ensembl
BHF-UCL
PMID:15358760 GO_REF:0000107 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G APOC3 apolipoprotein C3 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992
JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G APOC1 apolipoprotein C1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr 1:110,520,177...110,522,563
Ensembl chr 1:110,520,198...110,631,412
JBrowse link
G APOC2 apolipoprotein C2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:110,504,806...110,506,986
Ensembl chr 1:110,504,815...110,506,961
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 involved_in ISO (PMID:11099417) BHF-UCL PMID:11099417 NCBI chr10:46,261,747...46,300,084
Ensembl chr10:46,271,772...46,299,773
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 involved_in IEA Ensembl
Ensembl
GO_REF:0000107 NCBI chr10:46,300,142...46,319,592
Ensembl chr10:46,300,165...46,319,229
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
G MIR17 microRNA mir-17 involved_in ISO (PMID:23285084) ARUK-UCL PMID:23285084 NCBI chr22:42,478,013...42,478,071
Ensembl chr22:42,478,000...42,478,083
JBrowse link
G MIR27B microRNA mir-27b involved_in ISO (PMID:26520906) ARUK-UCL PMID:26520906 NCBI chr 1:71,678,117...71,678,179
Ensembl chr 1:71,678,105...71,678,191
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 5:54,197,211...54,210,724 JBrowse link
negative regulation of reverse cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MIR144 microRNA mir-144 involved_in ISO (PMID:24733347) ARUK-UCL PMID:24733347 NCBI chr 9:43,031,035...43,031,094
Ensembl chr 9:43,031,035...43,031,094
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16481
    negative regulation of biological process 5673
      negative regulation of transport 576
        negative regulation of lipid transport 53
          negative regulation of sterol transport 28
            negative regulation of cholesterol transport + 28
            negative regulation of intracellular sterol transport + 4
            negative regulation of sterol import 0
Path 2
Term Annotations click to browse term
  biological_process 16481
    localization 5270
      establishment of localization 4631
        transport 4466
          organic substance transport 2403
            lipid transport 419
              sterol transport 131
                regulation of sterol transport 79
                  negative regulation of sterol transport 28
                    negative regulation of cholesterol transport + 28
                    negative regulation of intracellular sterol transport + 4
                    negative regulation of sterol import 0
paths to the root