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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipid transport
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Accession:GO:0032369 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of lipid transport;   downregulation of lipid transport
 narrow_synonym: inhibition of lipid transport


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negative regulation of lipid transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hbp1 HMG-box transcription factor 1 ISO (MGI:MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:MGI:5754467 NCBI chrNW_004936479:16,855,368...16,886,210 JBrowse link
G Itgav integrin subunit alpha V ISO (PMID:15215180) BHF-UCL PMID:15215180 NCBI chrNW_004936506:10,750,116...10,839,018 JBrowse link
G Itgb3 integrin subunit beta 3 ISO (PMID:15215180) BHF-UCL PMID:15215180 NCBI chrNW_004936541:2,822,789...2,871,069 JBrowse link
G Nr1h2 nuclear receptor subfamily 1 group H member 2 ISO (PMID:17693624) BHF-UCL PMID:17693624 NCBI chrNW_004936889:223,137...229,968 JBrowse link
G Nr1h3 nuclear receptor subfamily 1 group H member 3 ISO (PMID:17693624) BHF-UCL PMID:17693624 NCBI chrNW_004936562:1,937,665...1,946,680 JBrowse link
negative regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO RGD PMID:9822642 RGD:13800919 NCBI chrNW_004936640:1,916,711...1,924,823 JBrowse link
G Hrh2 histamine receptor H2 ISO RGD PMID:1313563 RGD:9685527 NCBI chrNW_004936609:624,446...664,049 JBrowse link
G Pla2r1 phospholipase A2 receptor 1 ISO (MGI:MGI:5297792|PMID:11830583) UniProt PMID:11830583 MGI:MGI:5297792 NCBI chrNW_004936469:18,679,840...18,789,655 JBrowse link
negative regulation of bile acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnf tumor necrosis factor ISO RGD PMID:12563244 RGD:14995483 NCBI chrNW_004936727:1,936,066...1,937,766 JBrowse link
negative regulation of cholesterol efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
G Apoe apolipoprotein E ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
G Egf epidermal growth factor ISO (MGI:MGI:4460848|PMID:20037141) BHF-UCL PMID:20037141 MGI:MGI:4460848 NCBI chrNW_004936563:1,058,803...1,181,393 JBrowse link
G Irak1 interleukin 1 receptor associated kinase 1 ISO (MGI:MGI:4411947|PMID:19752193) UniProtKB PMID:19752193 MGI:MGI:4411947 NCBI chrNW_004936809:891,407...900,311 JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 ISO (MGI:MGI:5051938|PMID:20844270) BHF-UCL PMID:20844270 MGI:MGI:5051938 NCBI chrNW_004936501:2,841,209...2,857,570 JBrowse link
G Shh sonic hedgehog signaling molecule ISO (MGI:MGI:5306540|PMID:21931618) BHF-UCL PMID:21931618 MGI:MGI:5306540 NCBI chrNW_004936527:10,033,095...10,042,713 JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO (PMID:15358760) BHF-UCL PMID:15358760 NCBI chrNW_004936492:115,923...174,614 JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 ISO (PMID:10764676) BHF-UCL PMID:10764676 NCBI chrNW_004936903:520,420...521,726 JBrowse link
G Apoc3 apolipoprotein C3 ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004936542:2,106,927...2,108,412 JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 ISO (PMID:8636092) BHF-UCL PMID:8636092 NCBI chrNW_004936903:520,420...521,726 JBrowse link
G Apoc1 apolipoprotein C1 ISO (PMID:10978346) BHF-UCL PMID:10978346 NCBI chrNW_004936706:1,519,248...1,520,102 JBrowse link
G Apoc2 apolipoprotein C2 ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chrNW_004936706:1,531,219...1,531,921 JBrowse link
negative regulation of cholesterol transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoa2 apolipoprotein A2 ISO (PMID:8106353) BHF-UCL PMID:8106353 NCBI chrNW_004936903:520,420...521,726 JBrowse link
negative regulation of corticosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nrg1 neuregulin 1 ISO RGD PMID:21092742 RGD:10449008 NCBI chrNW_004936766:1,104,841...1,306,368 JBrowse link
negative regulation of cortisol secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn11 protein tyrosine phosphatase non-receptor type 11 ISO (MGI:MGI:3513751|PMID:15520383) MGI PMID:15520383 MGI:MGI:3513751 NCBI chrNW_004936668:2,602,261...2,687,903 JBrowse link
negative regulation of glucocorticoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cry1 cryptochrome circadian regulator 1 ISO (MGI:MGI:5495865|PMID:23531614) UniProtKB PMID:23531614 MGI:MGI:5495865 NCBI chrNW_004936492:7,929,138...7,994,797 JBrowse link
G Cry2 cryptochrome circadian regulator 2 ISO (MGI:MGI:5495865|PMID:23531614) UniProtKB PMID:23531614 MGI:MGI:5495865 NCBI chrNW_004936562:3,133,849...3,168,472 JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:18799632 RGD:2313549 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 ISO (PMID:11099417) BHF-UCL PMID:11099417 NCBI chrNW_004936508:8,093,804...8,117,467 JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO (PMID:11099417) BHF-UCL PMID:11099417 NCBI chrNW_004936508:8,074,697...8,093,424 JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg5 ATP binding cassette subfamily G member 5 ISO (PMID:11099417) BHF-UCL PMID:11099417 NCBI chrNW_004936508:8,093,804...8,117,467 JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 ISO (PMID:11099417) BHF-UCL PMID:11099417 NCBI chrNW_004936508:8,074,697...8,093,424 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004936621:620,163...639,115 JBrowse link
G Akt2 AKT serine/threonine kinase 2 ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004936661:2,652,568...2,694,039 JBrowse link
G Irs2 insulin receptor substrate 2 ISO (PMID:16814735) BHF-UCL PMID:16814735 NCBI chrNW_004936472:2,772,187...2,796,398 JBrowse link
G Thbs1 thrombospondin 1 ISO (PMID:17416590) BHF-UCL PMID:17416590 NCBI chrNW_004936471:3,064,466...3,081,125 JBrowse link
negative regulation of phospholipid efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chrNW_004936706:1,512,438...1,516,805 JBrowse link
negative regulation of progesterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 ISO (PMID:18703674) AgBase PMID:18703674 NCBI chrNW_004936595:919,807...935,367 JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long chain family member 4 ISO (PMID:21242590) UniProtKB PMID:21242590 NCBI chrNW_004936499:5,456,985...5,540,115 JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO RGD PMID:11581303, PMID:19474762 RGD:13800898, RGD:13800911 NCBI chrNW_004936640:1,916,711...1,924,823 JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004936522:6,271,339...6,300,202 JBrowse link
negative regulation of testosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp3 insulin like growth factor binding protein 3 ISO RGD PMID:25582342 RGD:12743617 NCBI chrNW_004936478:20,511,490...20,518,251 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11968
    negative regulation of biological process 4659
      negative regulation of lipid localization 47
        negative regulation of lipid transport 35
          negative regulation of acylglycerol transport + 0
          negative regulation of androstenedione secretion 0
          negative regulation of bile acid secretion 1
          negative regulation of dehydroepiandrosterone secretion 0
          negative regulation of estradiol secretion 0
          negative regulation of estrone secretion 0
          negative regulation of fatty acid transport + 9
          negative regulation of intestinal lipid absorption + 2
          negative regulation of intracellular lipid transport + 2
          negative regulation of juvenile hormone secretion 0
          negative regulation of lipid transport across blood-brain barrier 1
          negative regulation of lipid transporter activity + 1
          negative regulation of phospholipid transport + 1
          negative regulation of steroid hormone secretion + 5
          negative regulation of sterol transport + 14
          negative regulation of testosterone secretion 1
Path 2
Term Annotations click to browse term
  biological_process 11968
    localization 4765
      establishment of localization 3431
        transport 3286
          organic substance transport 1738
            lipid transport 270
              regulation of lipid transport 131
                negative regulation of lipid transport 35
                  negative regulation of acylglycerol transport + 0
                  negative regulation of androstenedione secretion 0
                  negative regulation of bile acid secretion 1
                  negative regulation of dehydroepiandrosterone secretion 0
                  negative regulation of estradiol secretion 0
                  negative regulation of estrone secretion 0
                  negative regulation of fatty acid transport + 9
                  negative regulation of intestinal lipid absorption + 2
                  negative regulation of intracellular lipid transport + 2
                  negative regulation of juvenile hormone secretion 0
                  negative regulation of lipid transport across blood-brain barrier 1
                  negative regulation of lipid transporter activity + 1
                  negative regulation of phospholipid transport + 1
                  negative regulation of steroid hormone secretion + 5
                  negative regulation of sterol transport + 14
                  negative regulation of testosterone secretion 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.