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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipid transport
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Accession:GO:0032369 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of lipid transport;   downregulation of lipid transport
 narrow_synonym: inhibition of lipid transport


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negative regulation of lipid transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HBP1 HMG-box transcription factor 1 ISO (MGI:MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:MGI:5754467 NCBI chr 9:106,966,060...106,993,915
Ensembl chr 9:106,965,947...106,996,048
JBrowse link
G ITGAV integrin subunit alpha V IEA Ensembl GO_REF:0000107 NCBI chr15:91,604,666...91,711,843
Ensembl chr15:91,604,676...91,711,840
JBrowse link
G ITGB3 integrin subunit beta 3 ISO (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr12:16,694,466...16,752,228
Ensembl chr12:16,693,505...16,752,292
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:55,238,536...55,245,457
Ensembl chr 6:55,237,953...55,245,456
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO (PMID:17693624) BHF-UCL PMID:17693624 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,270,789...15,334,820
JBrowse link
negative regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5PF ATP synthase peripheral stalk subunit F6 ISO RGD PMID:9822642 RGD:13800919 NCBI chr13:189,281,429...189,290,234
Ensembl chr13:189,278,945...189,290,229
JBrowse link
G HRH2 histamine receptor H2 ISO RGD PMID:1313563 RGD:9685527 NCBI chr 2:81,883,670...81,932,464
Ensembl chr 2:81,883,670...81,932,275
JBrowse link
G PLA2R1 phospholipase A2 receptor 1 ISO (MGI:MGI:5297792|PMID:11830583) UniProt PMID:11830583 MGI:MGI:5297792 NCBI chr15:66,899,783...67,018,608
Ensembl chr15:66,898,508...67,001,163
JBrowse link
negative regulation of bile acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNF tumor necrosis factor ISO RGD PMID:12563244 RGD:14995483 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,636...23,703,655
JBrowse link
negative regulation of cholesterol efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484
G APOE apolipoprotein E ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
G EGF epidermal growth factor IEA Ensembl GO_REF:0000107 NCBI chr 8:112,235,607...112,330,062
Ensembl chr 8:112,234,365...112,330,046
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO (MGI:MGI:4411947|PMID:19752193) UniProtKB PMID:19752193 MGI:MGI:4411947 NCBI chr  X:124,717,604...124,724,855
Ensembl chr  X:124,717,612...124,724,860
JBrowse link
G LOC110259864 group 10 secretory phospholipase A2-like IEA Ensembl GO_REF:0000107 NCBI chr 3:7,623,326...7,641,061
Ensembl chr 3:7,623,311...7,641,082
JBrowse link
G SHH sonic hedgehog signaling molecule IEA Ensembl GO_REF:0000107 NCBI chr18:2,546,202...2,555,484
Ensembl chr18:2,545,718...2,555,484
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 IEA Ensembl GO_REF:0000107 NCBI chr 5:6,719,484...6,784,724
Ensembl chr 5:6,719,487...6,784,672
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320
JBrowse link
G APOC3 apolipoprotein C3 IEA Ensembl GO_REF:0000107 NCBI chr 9:44,211,171...44,213,538 JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 ISO (PMID:8636092) BHF-UCL PMID:8636092 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320
JBrowse link
G APOC2 apolipoprotein C2 ISO (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr 6:51,404,219...51,406,302 JBrowse link
negative regulation of cholesterol transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IEA Ensembl GO_REF:0000107 NCBI chr 4:89,237,514...89,239,126
Ensembl chr 4:89,237,511...89,240,320
JBrowse link
negative regulation of corticosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRG1 neuregulin 1 ISO RGD PMID:21092742 RGD:10449008 NCBI chr15:52,625,550...53,688,003
Ensembl chr15:52,627,334...53,688,332
JBrowse link
negative regulation of cortisol secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEA Ensembl GO_REF:0000107 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,168...39,292,018
JBrowse link
negative regulation of glucocorticoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRY1 cryptochrome circadian regulator 1 IEA Ensembl GO_REF:0000107 NCBI chr 5:13,275,265...13,429,566
Ensembl chr 5:13,275,544...13,364,594
JBrowse link
G CRY2 cryptochrome circadian regulator 2 IEA Ensembl GO_REF:0000107 NCBI chr 2:16,587,101...16,620,380
Ensembl chr 2:16,585,966...16,620,405
JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:18799632 RGD:2313549 NCBI chr  X:95,267,709...95,272,237
Ensembl chr  X:95,269,300...95,270,388
JBrowse link
G CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 ISO (PMID:18391101) UniProtKB PMID:18391101 NCBI chr 2:61,745,069...61,759,971 JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 IEA Ensembl GO_REF:0000107 NCBI chr 3:96,616,304...96,656,893
Ensembl chr 3:96,616,246...96,656,893
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 IEA Ensembl GO_REF:0000107 NCBI chr 3:96,596,975...96,616,224
Ensembl chr 3:96,594,778...96,616,229
JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 IEA Ensembl GO_REF:0000107 NCBI chr 3:96,616,304...96,656,893
Ensembl chr 3:96,616,246...96,656,893
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 IEA Ensembl GO_REF:0000107 NCBI chr 3:96,596,975...96,616,224
Ensembl chr 3:96,594,778...96,616,229
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 ISO (PMID:16814735) BHF-UCL PMID:16814735
G AKT2 AKT serine/threonine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:48,555,785...48,620,472
Ensembl chr 6:48,555,789...48,587,919
JBrowse link
G IRS2 insulin receptor substrate 2 IEA Ensembl GO_REF:0000107 NCBI chr11:76,626,158...76,654,639
Ensembl chr11:76,626,179...76,653,881
JBrowse link
G THBS1 thrombospondin 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:131,728,781...131,746,098
Ensembl chr 1:131,728,781...131,746,115
JBrowse link
negative regulation of phospholipid efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 6:51,373,113...51,375,333
Ensembl chr 6:51,372,259...51,377,794
JBrowse link
negative regulation of progesterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 IMP (PMID:18703674) AgBase PMID:18703674 NCBI chr12:52,939,643...52,953,786
Ensembl chr12:52,939,643...52,953,819
JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO (PMID:21242590) UniProtKB PMID:21242590 NCBI chr  X:89,760,863...89,838,103
Ensembl chr  X:89,760,865...89,837,678
JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 ISO RGD PMID:11581303, PMID:19474762 RGD:13800898, RGD:13800911 NCBI chr13:189,281,429...189,290,234
Ensembl chr13:189,278,945...189,290,229
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484
G PCSK9 proprotein convertase subtilisin/kexin type 9 IEA Ensembl GO_REF:0000107 NCBI chr 6:157,388,370...157,409,620
Ensembl chr 6:157,388,372...157,409,604
JBrowse link
negative regulation of testosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:25582342 RGD:12743617 NCBI chr18:50,002,921...50,009,425 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    negative regulation of biological process 5357
      negative regulation of lipid localization 50
        negative regulation of lipid transport 35
          negative regulation of acylglycerol transport + 0
          negative regulation of androstenedione secretion 0
          negative regulation of bile acid secretion 1
          negative regulation of dehydroepiandrosterone secretion 0
          negative regulation of estradiol secretion 0
          negative regulation of estrone secretion 0
          negative regulation of fatty acid transport + 10
          negative regulation of intestinal lipid absorption + 2
          negative regulation of intracellular lipid transport + 2
          negative regulation of juvenile hormone secretion 0
          negative regulation of lipid transport across blood-brain barrier 1
          negative regulation of lipid transporter activity + 1
          negative regulation of phospholipid transport + 1
          negative regulation of steroid hormone secretion + 5
          negative regulation of sterol transport + 13
          negative regulation of testosterone secretion 1
Path 2
Term Annotations click to browse term
  biological_process 16524
    localization 5919
      establishment of localization 4439
        transport 4298
          organic substance transport 2378
            lipid transport 375
              regulation of lipid transport 145
                negative regulation of lipid transport 35
                  negative regulation of acylglycerol transport + 0
                  negative regulation of androstenedione secretion 0
                  negative regulation of bile acid secretion 1
                  negative regulation of dehydroepiandrosterone secretion 0
                  negative regulation of estradiol secretion 0
                  negative regulation of estrone secretion 0
                  negative regulation of fatty acid transport + 10
                  negative regulation of intestinal lipid absorption + 2
                  negative regulation of intracellular lipid transport + 2
                  negative regulation of juvenile hormone secretion 0
                  negative regulation of lipid transport across blood-brain barrier 1
                  negative regulation of lipid transporter activity + 1
                  negative regulation of phospholipid transport + 1
                  negative regulation of steroid hormone secretion + 5
                  negative regulation of sterol transport + 13
                  negative regulation of testosterone secretion 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.