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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipid transport
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Accession:GO:0032369 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of lipid transport;   downregulation of lipid transport
 narrow_synonym: inhibition of lipid transport


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negative regulation of lipid transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HBP1 HMG-box transcription factor 1 ISO (MGI:MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:MGI:5754467 NCBI chr 7:107,168,987...107,202,523
Ensembl chr 7:107,168,961...107,202,522
JBrowse link
G ITGAV integrin subunit alpha V IMP (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,056...186,680,901
JBrowse link
G ITGB3 integrin subunit beta 3 IMP (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr17:47,253,827...47,313,743
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
Ensembl chr17:47,253,846...47,313,735
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 IMP (PMID:17693624) BHF-UCL PMID:17693624 NCBI chr19:50,376,457...50,383,388
Ensembl chr19:50,329,653...50,383,388
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 IMP (PMID:17693624) BHF-UCL PMID:17693624 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033
JBrowse link
negative regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5PF ATP synthase peripheral stalk subunit F6 IEA Ensembl GO_REF:0000107 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673
JBrowse link
G HRH2 histamine receptor H2 ISO RGD PMID:1313563 RGD:9685527 NCBI chr 5:175,657,762...175,710,756
Ensembl chr 5:175,658,030...175,710,756
JBrowse link
G PLA2R1 phospholipase A2 receptor 1 ISS UniProtKB GO_REF:0000024 NCBI chr 2:159,932,002...160,062,615
Ensembl chr 2:159,932,006...160,062,615
JBrowse link
negative regulation of bile acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNF tumor necrosis factor ISO RGD PMID:12563244 RGD:14995483 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
negative regulation of cholesterol efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G APOE apolipoprotein E IDA (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
G EGF epidermal growth factor IEA Ensembl GO_REF:0000107 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO (MGI:MGI:4411947|PMID:19752193) UniProtKB PMID:19752193 MGI:MGI:4411947 NCBI chr  X:154,010,507...154,019,984
Ensembl chr  X:154,010,506...154,019,902
JBrowse link
G PLA2G10 phospholipase A2 group X ISS (PMID:20844270) BHF-UCL PMID:20844270 NCBI chr16:14,672,548...14,694,662
Ensembl chr16:14,672,545...14,694,669
Ensembl chr16:14,672,545...14,694,669
JBrowse link
G SHH sonic hedgehog signaling molecule ISS BHF-UCL GO_REF:0000024 NCBI chr 7:155,799,980...155,812,463
Ensembl chr 7:155,799,980...155,812,463
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 IDA (PMID:15358760) BHF-UCL PMID:15358760 NCBI chr22:41,833,105...41,907,308
Ensembl chr22:41,833,079...41,907,307
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IDA (PMID:10764676) BHF-UCL PMID:10764676 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G APOC3 apolipoprotein C3 IMP (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr11:116,829,907...116,833,072
Ensembl chr11:116,829,706...116,833,072
JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IMP (PMID:8636092) BHF-UCL PMID:8636092 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
G APOC1 apolipoprotein C1 IDA
IBA
(PMID:10978346)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:10978346, PMID:21873635 NCBI chr19:44,914,325...44,919,346
Ensembl chr19:44,914,247...44,919,349
JBrowse link
G APOC2 apolipoprotein C2 IMP (PMID:15778093) BHF-UCL PMID:15778093 NCBI chr19:44,946,051...44,949,565
Ensembl chr19:44,945,971...44,949,566
Ensembl chr19:44,945,971...44,949,566
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 IC (PMID:16938301) BHF-UCL PMID:16938301 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
negative regulation of cholesterol transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IDA (PMID:8106353) BHF-UCL PMID:8106353 NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
JBrowse link
negative regulation of corticosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRG1 neuregulin 1 ISO RGD PMID:21092742 RGD:10449008 NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
JBrowse link
negative regulation of cortisol secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEA Ensembl GO_REF:0000107 NCBI chr12:112,418,915...112,509,918
Ensembl chr12:112,418,351...112,509,913
Ensembl chr12:112,418,351...112,509,913
JBrowse link
negative regulation of glucocorticoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRY1 cryptochrome circadian regulator 1 IEA Ensembl GO_REF:0000107 NCBI chr12:106,991,364...107,093,872
Ensembl chr12:106,991,364...107,093,549
JBrowse link
G CRY2 cryptochrome circadian regulator 2 IEA Ensembl GO_REF:0000107 NCBI chr11:45,847,118...45,883,244
Ensembl chr11:45,847,118...45,883,248
JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974
JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 IMP (PMID:18391101) UniProtKB PMID:18391101 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 IMP (PMID:11099417) BHF-UCL PMID:11099417 NCBI chr 2:43,806,154...43,838,840
Ensembl chr 2:43,812,472...43,838,865
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 IMP (PMID:11099417) BHF-UCL PMID:11099417 NCBI chr 2:43,831,942...43,882,988
Ensembl chr 2:43,831,942...43,882,988
JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 IMP (PMID:11099417) BHF-UCL PMID:11099417 NCBI chr 2:43,806,154...43,838,840
Ensembl chr 2:43,812,472...43,838,865
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 IMP (PMID:11099417) BHF-UCL PMID:11099417 NCBI chr 2:43,831,942...43,882,988
Ensembl chr 2:43,831,942...43,882,988
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E IDA (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IMP (PMID:16814735) BHF-UCL PMID:16814735 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G AKT2 AKT serine/threonine kinase 2 IMP (PMID:16814735) BHF-UCL PMID:16814735 NCBI chr19:40,230,317...40,285,531
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G IRS2 insulin receptor substrate 2 IMP (PMID:16814735) BHF-UCL PMID:16814735 NCBI chr13:109,752,695...109,786,583
Ensembl chr13:109,752,695...109,786,583
JBrowse link
G THBS1 thrombospondin 1 IDA (PMID:17416590) BHF-UCL PMID:17416590 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466
JBrowse link
negative regulation of phospholipid efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E IDA (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393
JBrowse link
negative regulation of progesterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 ISO (PMID:18703674) AgBase PMID:18703674 NCBI chr17:7,668,402...7,687,550
Ensembl chr17:7,661,779...7,687,538
Ensembl chr17:7,661,779...7,687,538
JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL4 acyl-CoA synthetase long chain family member 4 IDA (PMID:21242590) UniProtKB PMID:21242590 NCBI chr  X:109,641,335...109,733,325
Ensembl chr  X:109,624,244...109,733,403
JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 IEA Ensembl GO_REF:0000107 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 IDA (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,922
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 IDA (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
negative regulation of testosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:25582342 RGD:12743617 NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18626
    negative regulation of biological process 6190
      negative regulation of lipid localization 53
        negative regulation of lipid transport 37
          negative regulation of acylglycerol transport + 0
          negative regulation of androstenedione secretion 0
          negative regulation of bile acid secretion 1
          negative regulation of dehydroepiandrosterone secretion 0
          negative regulation of estradiol secretion 0
          negative regulation of estrone secretion 0
          negative regulation of fatty acid transport + 10
          negative regulation of intestinal lipid absorption + 2
          negative regulation of intracellular lipid transport + 2
          negative regulation of juvenile hormone secretion 0
          negative regulation of lipid transport across blood-brain barrier 1
          negative regulation of lipid transporter activity + 1
          negative regulation of phospholipid transport + 1
          negative regulation of steroid hormone secretion + 5
          negative regulation of sterol transport + 15
          negative regulation of testosterone secretion 1
Path 2
Term Annotations click to browse term
  biological_process 18626
    localization 7211
      establishment of localization 5679
        transport 5545
          organic substance transport 3019
            lipid transport 423
              regulation of lipid transport 150
                negative regulation of lipid transport 37
                  negative regulation of acylglycerol transport + 0
                  negative regulation of androstenedione secretion 0
                  negative regulation of bile acid secretion 1
                  negative regulation of dehydroepiandrosterone secretion 0
                  negative regulation of estradiol secretion 0
                  negative regulation of estrone secretion 0
                  negative regulation of fatty acid transport + 10
                  negative regulation of intestinal lipid absorption + 2
                  negative regulation of intracellular lipid transport + 2
                  negative regulation of juvenile hormone secretion 0
                  negative regulation of lipid transport across blood-brain barrier 1
                  negative regulation of lipid transporter activity + 1
                  negative regulation of phospholipid transport + 1
                  negative regulation of steroid hormone secretion + 5
                  negative regulation of sterol transport + 15
                  negative regulation of testosterone secretion 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.