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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of lipid transport
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Accession:GO:0032369 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
Synonyms:exact_synonym: down regulation of lipid transport;   downregulation of lipid transport
 narrow_synonym: inhibition of lipid transport


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negative regulation of lipid transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HBP1 HMG-box transcription factor 1 ISO (MGI:MGI:5754467|PMID:24675724) BHF-UCL PMID:24675724 MGI:MGI:5754467 NCBI chr18:13,339,359...13,368,105
Ensembl chr18:13,340,287...13,367,915
JBrowse link
G ITGAV integrin subunit alpha V IEA Ensembl GO_REF:0000107 NCBI chr36:28,815,215...28,890,569
Ensembl chr36:28,804,013...28,887,430
JBrowse link
G ITGB3 integrin subunit beta 3 ISO (PMID:15215180) BHF-UCL PMID:15215180 NCBI chr 9:9,179,667...9,231,061
Ensembl chr 9:9,182,562...9,231,451
JBrowse link
G NR1H2 nuclear receptor subfamily 1 group H member 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:106,332,691...106,339,168
Ensembl chr 1:106,332,798...106,339,135
JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 ISO (PMID:17693624) BHF-UCL PMID:17693624 NCBI chr18:42,333,173...42,346,152
Ensembl chr18:42,333,202...42,341,236
JBrowse link
negative regulation of arachidonic acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP5PF ATP synthase peripheral stalk subunit F6 ISO RGD PMID:9822642 RGD:13800919 NCBI chr31:21,207,080...21,212,220
Ensembl chr31:21,200,337...21,215,975
JBrowse link
G HRH2 histamine receptor H2 ISO RGD PMID:1313563 RGD:9685527 NCBI chr 4:37,333,843...37,407,146
Ensembl chr 4:37,275,852...37,386,072
JBrowse link
G PLA2R1 phospholipase A2 receptor 1 ISO (MGI:MGI:5297792|PMID:11830583) UniProt PMID:11830583 MGI:MGI:5297792 NCBI chr36:5,696,733...5,793,599
Ensembl chr36:5,698,429...5,794,204
JBrowse link
negative regulation of bile acid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNF tumor necrosis factor ISO RGD PMID:12563244 RGD:14995483 NCBI chr12:1,074,561...1,076,425
Ensembl chr12:1,074,552...1,076,425
JBrowse link
negative regulation of cholesterol efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
G APOE apolipoprotein E ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
G EGF epidermal growth factor IEA Ensembl GO_REF:0000107 NCBI chr32:30,073,541...30,166,904
Ensembl chr32:30,073,950...30,166,295
JBrowse link
G IRAK1 interleukin 1 receptor associated kinase 1 ISO (MGI:MGI:4411947|PMID:19752193) UniProtKB PMID:19752193 MGI:MGI:4411947 NCBI chr  X:121,853,340...121,862,582
Ensembl chr  X:121,819,432...121,862,576
JBrowse link
G PLA2G10 phospholipase A2 group X IEA Ensembl GO_REF:0000107 NCBI chr 6:28,573,239...28,591,714
Ensembl chr 6:28,574,387...28,591,703
JBrowse link
G SHH sonic hedgehog signaling molecule IEA Ensembl GO_REF:0000107 NCBI chr16:18,650,553...18,663,571
Ensembl chr16:18,484,809...18,662,903
JBrowse link
G SREBF2 sterol regulatory element binding transcription factor 2 IEA Ensembl GO_REF:0000107 NCBI chr10:23,451,923...23,532,765
Ensembl chr10:23,452,561...23,518,689
Ensembl chr10:23,452,561...23,518,689
JBrowse link
negative regulation of cholesterol import term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IEA Ensembl GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G APOC3 apolipoprotein C3 IEA Ensembl GO_REF:0000107 NCBI chr 5:16,744,423...16,746,992
Ensembl chr 5:16,744,423...16,746,992
JBrowse link
negative regulation of cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 ISO (PMID:8636092) BHF-UCL PMID:8636092 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
G APOC1 apolipoprotein C1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 1:110,520,177...110,522,563
Ensembl chr 1:110,520,198...110,631,412
JBrowse link
G APOC2 apolipoprotein C2 IEA Ensembl GO_REF:0000107 NCBI chr 1:110,504,806...110,506,986
Ensembl chr 1:110,504,815...110,506,961
JBrowse link
negative regulation of cholesterol transporter activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOA2 apolipoprotein A2 IEA Ensembl GO_REF:0000107 NCBI chr38:21,263,641...21,265,887
Ensembl chr38:21,262,789...21,265,887
JBrowse link
negative regulation of corticosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NRG1 neuregulin 1 ISO RGD PMID:21092742 RGD:10449008 NCBI chr16:31,697,958...32,771,888
Ensembl chr16:31,706,851...32,771,932
JBrowse link
negative regulation of cortisol secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTPN11 protein tyrosine phosphatase non-receptor type 11 IEA Ensembl GO_REF:0000107 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481
JBrowse link
negative regulation of glucocorticoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRY1 cryptochrome circadian regulator 1 IEA Ensembl GO_REF:0000107 NCBI chr10:31,681,098...31,792,995
Ensembl chr10:31,681,288...31,780,306
JBrowse link
G CRY2 cryptochrome circadian regulator 2 IEA Ensembl GO_REF:0000107 NCBI chr18:43,538,335...43,573,651
Ensembl chr18:43,539,612...43,573,875
JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:18799632 RGD:2313549 NCBI chr  X:88,703,551...88,708,451
Ensembl chr  X:88,705,765...88,706,853
JBrowse link
negative regulation of intestinal cholesterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 IEA Ensembl GO_REF:0000107 NCBI chr10:46,261,747...46,300,084
Ensembl chr10:46,271,772...46,299,773
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 IEA Ensembl GO_REF:0000107 NCBI chr10:46,300,142...46,319,592
Ensembl chr10:46,300,165...46,319,229
JBrowse link
negative regulation of intestinal phytosterol absorption term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCG5 ATP binding cassette subfamily G member 5 IEA Ensembl GO_REF:0000107 NCBI chr10:46,261,747...46,300,084
Ensembl chr10:46,271,772...46,299,773
JBrowse link
G ABCG8 ATP binding cassette subfamily G member 8 IEA Ensembl GO_REF:0000107 NCBI chr10:46,300,142...46,319,592
Ensembl chr10:46,300,165...46,319,229
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
negative regulation of long-chain fatty acid import across plasma membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AKT1 AKT serine/threonine kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr 8:72,317,399...72,335,686
Ensembl chr 8:72,317,869...72,335,193
JBrowse link
G AKT2 AKT serine/threonine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 1:113,359,038...113,407,119
Ensembl chr 1:113,359,575...113,407,131
JBrowse link
G IRS2 insulin receptor substrate 2 IEA Ensembl GO_REF:0000107 NCBI chr22:58,197,016...58,229,026
Ensembl chr22:58,223,387...58,227,535
JBrowse link
G THBS1 thrombospondin 1 IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
negative regulation of phospholipid efflux term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E ISO (PMID:12042316) Alzheimers_University_of_Toronto PMID:12042316 NCBI chr 1:110,525,717...110,528,534
Ensembl chr 1:110,525,722...110,528,440
JBrowse link
negative regulation of progesterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TP53 tumor protein p53 ISO (PMID:18703674) AgBase PMID:18703674 NCBI chr 5:32,561,406...32,565,149
Ensembl chr 5:32,560,598...32,574,109
JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSL4 acyl-CoA synthetase long chain family member 4 ISO (PMID:21242590) UniProtKB PMID:21242590 NCBI chr  X:82,864,506...82,943,984
Ensembl chr  X:82,866,823...82,916,789
JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 ISO RGD PMID:11581303, PMID:19474762 RGD:13800898, RGD:13800911 NCBI chr31:21,207,080...21,212,220
Ensembl chr31:21,200,337...21,215,975
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 5:54,197,211...54,210,724 JBrowse link
negative regulation of testosterone secretion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGFBP3 insulin like growth factor binding protein 3 ISO RGD PMID:25582342 RGD:12743617 NCBI chr16:1,021,855...1,027,604
Ensembl chr16:1,021,972...1,026,392
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16162
    negative regulation of biological process 5384
      negative regulation of lipid localization 50
        negative regulation of lipid transport 35
          negative regulation of acylglycerol transport + 0
          negative regulation of androstenedione secretion 0
          negative regulation of bile acid secretion 1
          negative regulation of dehydroepiandrosterone secretion 0
          negative regulation of estradiol secretion 0
          negative regulation of estrone secretion 0
          negative regulation of fatty acid transport + 9
          negative regulation of intestinal lipid absorption + 2
          negative regulation of intracellular lipid transport + 2
          negative regulation of juvenile hormone secretion 0
          negative regulation of lipid transport across blood-brain barrier 1
          negative regulation of lipid transporter activity + 1
          negative regulation of phospholipid transport + 1
          negative regulation of steroid hormone secretion + 5
          negative regulation of sterol transport + 14
          negative regulation of testosterone secretion 1
Path 2
Term Annotations click to browse term
  biological_process 16162
    localization 5963
      establishment of localization 4479
        transport 4337
          organic substance transport 2397
            lipid transport 361
              regulation of lipid transport 137
                negative regulation of lipid transport 35
                  negative regulation of acylglycerol transport + 0
                  negative regulation of androstenedione secretion 0
                  negative regulation of bile acid secretion 1
                  negative regulation of dehydroepiandrosterone secretion 0
                  negative regulation of estradiol secretion 0
                  negative regulation of estrone secretion 0
                  negative regulation of fatty acid transport + 9
                  negative regulation of intestinal lipid absorption + 2
                  negative regulation of intracellular lipid transport + 2
                  negative regulation of juvenile hormone secretion 0
                  negative regulation of lipid transport across blood-brain barrier 1
                  negative regulation of lipid transporter activity + 1
                  negative regulation of phospholipid transport + 1
                  negative regulation of steroid hormone secretion + 5
                  negative regulation of sterol transport + 14
                  negative regulation of testosterone secretion 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.