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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO (PMID:10431236) BHF-UCL PMID:10431236 NCBI chrNW_004936559:7,177,887...7,312,660 JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 ISO (PMID:15994327) BHF-UCL PMID:15994327 NCBI chrNW_004936500:1,620,763...1,678,561 JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) UniProtKB PMID:9211849 PMID:27238017 PMID:28784760 NCBI chrNW_004936550:2,983,172...3,032,222 JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 ISO (PMID:17018531), (PMID:18823126)
(MGI:3763329|PMID:17018531)
(PMID:19723497)
(PMID:15937921), (PMID:27238017)		 HGNC
HGNC-UCL
MGI
UniProtKB		 PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017 MGI:3763329 NCBI chrNW_004936488:3,664,171...3,676,438 JBrowse link
G Osbp oxysterol binding protein ISO (PMID:29514919) UniProtKB PMID:29514919 NCBI chrNW_004936581:3,118,198...3,148,882 JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing ISO (PMID:29514919) UniProtKB PMID:29514919 NCBI chrNW_004936497:3,021,962...3,121,028 JBrowse link
G Scp2 sterol carrier protein 2 ISO (PMID:7642518) UniProt PMID:7642518 NCBI chrNW_004936522:8,004,503...8,110,995 JBrowse link
G Serac1 serine active site containing 1 ISO (PMID:22683713) UniProtKB PMID:22683713 NCBI chrNW_004936489:9,911,484...9,983,826 JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:14617579 RGD:4145640 NCBI chrNW_004936710:1,523,289...1,530,181 JBrowse link
G Stard4 StAR related lipid transfer domain containing 4 ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004936531:5,865,840...5,877,591 JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A ISO (PMID:10637304) UniProtKB PMID:10637304 NCBI chrNW_004936475:19,432,311...19,444,223 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004936669:922,978...941,996 JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004936522:6,271,339...6,300,202 JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2 ISO (PMID:15449949) UniProtKB PMID:15449949 NCBI chrNW_004936522:8,004,503...8,110,995 JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)		 BHF-UCL PMID:22848640 MGI:5446858 NCBI chrNW_004936471:21,274,112...21,329,286 JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004936474:10,196,228...10,219,137 JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor ISO (PMID:6299582) BHF-UCL PMID:6299582 NCBI chrNW_004936659:1,259,405...1,300,545 JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004936474:10,196,228...10,219,137 JBrowse link
G Lrp6 LDL receptor related protein 6 ISO (MGI:4413421|PMID:18948618) MGI PMID:18948618 MGI:4413421 NCBI chrNW_004936587:5,065,200...5,143,029 JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:15238223)
(MGI:6478054|PMID:22748276)		 UniProtKB
UniProt		 PMID:15238223 PMID:22748276 MGI:6478054 NCBI chrNW_004936669:922,978...941,996 JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator ISO (PMID:20663892) UniProtKB PMID:20663892 NCBI chrNW_004936484:19,551,293...19,562,132 JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO (PMID:19723497)
(MGI:4358633|PMID:19723497)		 MGI PMID:19723497 MGI:4358633 NCBI chrNW_004936658:695,431...718,891 JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO (PMID:29353240) UniProt PMID:29353240 NCBI chrNW_004936520:5,383,737...5,540,176 JBrowse link
G Syt7 synaptotagmin 7 ISO (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chrNW_004936581:1,516,199...1,557,992 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12031
    localization 4792
      cellular localization 2350
        intracellular transport 1062
          intracellular lipid transport 26
            intracellular sterol transport 21
              intracellular cholesterol transport 21
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 3
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 7
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 12031
    localization 4792
      establishment of localization 3432
        transport 3269
          ion transport 2335
            anion transport 1780
              organic substance transport 1704
                lipid transport 339
                  sterol transport 89
                    cholesterol transport 89
                      intracellular cholesterol transport 21
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 3
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 7
                        vesicle-mediated cholesterol transport + 2
paths to the root