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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO (PMID:10431236) RGD PMID:10431236 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,743,269...9,842,735
Ensembl chr20:9,743,269...9,840,489 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) RGD PMID:9211849 PMID:27238017 PMID:28784760 NCBI chr18:3,616,878...3,662,656
Ensembl chr18:3,616,878...3,662,683 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 ISO
IBA		 UniProtKB:Q96E22 (PMID:15937921), (PMID:17018531), (PMID:18823126), (PMID:19723497), (PMID:27238017)
PMID:21873635
(MGI:3763329|PMID:17018531)		 RGD PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017, PMID:21873635 MGI:3763329, RGD:13792537 NCBI chr 6:108,467,410...108,488,330
Ensembl chr 6:108,467,410...108,488,330 		JBrowse link
G Osbp oxysterol binding protein ISO (PMID:29514919) RGD PMID:29514919 NCBI chr 1:228,395,237...228,425,366
Ensembl chr 1:228,395,558...228,425,361 		JBrowse link
G Osbpl2 oxysterol binding protein-like 2 ISO
IEA		 (PMID:30581148)
GO_REF:0000107		 RGD
Ensembl		 PMID:30581148 GO_REF:0000107 NCBI chr 3:175,493,650...175,538,965
Ensembl chr 3:175,493,698...175,538,963 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:70,192,975...70,215,719
Ensembl chr 8:70,192,975...70,215,719 		JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing ISO (PMID:29514919) RGD PMID:29514919 NCBI chr13:25,656,983...25,752,792
Ensembl chr13:25,656,983...25,752,792 		JBrowse link
G Scp2 sterol carrier protein 2 ISO
ISS		 (PMID:7642518)
GO_REF:0000024		 RGD
UniProt		 PMID:7642518 GO_REF:0000024 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739 		JBrowse link
G Serac1 serine active site containing 1 ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,934,499...46,978,264
Ensembl chr 1:46,942,192...46,978,261 		JBrowse link
G Star steroidogenic acute regulatory protein IEP
IBA		 PMID:21873635 RGD
GO_Central		 PMID:14617579, PMID:21873635 RGD:4145640, RGD:13792537 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847 		JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 ISO
IBA		 (PMID:18403318)
PMID:21873635		 RGD PMID:18403318, PMID:21873635 RGD:13792537 NCBI chr18:25,982,210...25,997,555
Ensembl chr18:25,984,638...25,997,555 		JBrowse link
G Tspo2 translocator protein 2 ISO
IEA		 (PMID:32358067)
(MGI:6450299|PMID:32358067)
GO_REF:0000107		 RGD
Ensembl		 PMID:32358067 GO_REF:0000107 MGI:6450299 NCBI chr 9:14,510,378...14,514,609
Ensembl chr 9:14,513,037...14,514,416 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A ISO (PMID:10637304) RGD PMID:10637304 NCBI chr19:39,230,050...39,243,298
Ensembl chr19:39,229,754...39,243,496 		JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:126,031,368...126,053,726
Ensembl chr 5:126,031,368...126,053,726 		JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2 ISO
IBA		 (PMID:15449949)
PMID:21873635		 RGD PMID:15449949, PMID:21873635 RGD:13792537 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739 		JBrowse link
G Scp2d1 SCP2 sterol-binding domain containing 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:138,973,171...138,975,624
Ensembl chr 3:138,974,871...138,975,621 		JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)		 RGD PMID:22848640 MGI:5446858 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211 		JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor ISO (PMID:6299582) RGD PMID:6299582 NCBI chr 8:22,750,425...22,773,305
Ensembl chr 8:22,750,336...22,774,903 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:152,964,294...152,987,286
Ensembl chr 5:152,966,591...152,987,211 		JBrowse link
G Lrp6 LDL receptor related protein 6 ISO
IBA		 MGI:4123883 (MGI:4413421|PMID:18948618)
PMID:21873635		 RGD PMID:18948618, PMID:21873635 MGI:4413421, RGD:13792537 NCBI chr 4:168,194,054...168,323,962
Ensembl chr 4:168,194,927...168,323,751 		JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO
ISS		 (PMID:15238223)
(MGI:6478054|PMID:22748276)
GO_REF:0000024		 RGD
UniProt		 PMID:15238223 PMID:22748276 GO_REF:0000024 MGI:6478054 NCBI chr 3:2,648,787...2,668,770
Ensembl chr 3:2,648,885...2,668,809 		JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator ISO (PMID:20663892) RGD PMID:20663892 NCBI chr19:57,484,720...57,496,539
Ensembl chr19:57,484,634...57,496,695 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO UniProtKB:P61916 (PMID:19723497)
(MGI:4358633|PMID:19723497)		 RGD PMID:19723497 MGI:4358633 NCBI chr20:33,557,052...33,584,011
Ensembl chr20:33,557,052...33,584,010 		JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO
ISS		 (PMID:29353240)
GO_REF:0000024		 RGD
UniProt		 PMID:29353240 GO_REF:0000024 NCBI chr17:85,533,056...85,748,843 JBrowse link
G Syt7 synaptotagmin 7 ISS
ISO		 GO_REF:0000024
(MGI:5645834|PMID:25860611)		 UniProt
RGD		 PMID:25860611 GO_REF:0000024 MGI:5645834 NCBI chr 1:226,435,816...226,498,008
Ensembl chr 1:226,435,979...226,493,377 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20044
    localization 6483
      cellular localization 2988
        intracellular transport 1517
          intracellular lipid transport 33
            intracellular sterol transport 25
              intracellular cholesterol transport 25
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 4
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 8
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 20044
    localization 6483
      establishment of localization 4908
        transport 4745
          ion transport 3509
            anion transport 2693
              organic substance transport 2569
                lipid transport 479
                  sterol transport 115
                    cholesterol transport 101
                      intracellular cholesterol transport 25
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 4
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 8
                        vesicle-mediated cholesterol transport + 2
paths to the root