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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 ISO (PMID:10431236) BHF-UCL PMID:10431236 NCBI chr 1:246,144,277...246,278,492
Ensembl chr 1:246,144,277...246,278,492 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 IEA InterPro GO_REF:0000002 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:108,403,126...108,450,486
Ensembl chr 6:108,402,877...108,450,990 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 ISS
IBA
IEA		 (PMID:21873635) UniProt
GO_Central
Ensembl
InterPro		 PMID:21873635 GO_REF:0000002 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:97,730,532...97,740,087
Ensembl chr 7:97,730,514...97,740,331 		JBrowse link
G OSBP oxysterol binding protein IEA Ensembl GO_REF:0000107 NCBI chr 2:11,876,294...11,911,660
Ensembl chr 2:11,875,844...11,911,656 		JBrowse link
G OSBPL2 oxysterol binding protein like 2 IEA Ensembl GO_REF:0000107 NCBI chr17:61,643,263...61,683,178
Ensembl chr17:61,643,366...61,685,819 		JBrowse link
G RAB11A RAB11A, member RAS oncogene family ISS UniProt GO_REF:0000024 NCBI chr 1:163,858,254...163,887,741
Ensembl chr 1:163,858,123...163,894,347 		JBrowse link
G RELCH RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:159,207,951...159,317,675
Ensembl chr 1:159,207,616...159,317,641 		JBrowse link
G SCP2 sterol carrier protein 2 ISO (PMID:7642518) UniProt PMID:7642518 NCBI chr 6:159,191,045...159,314,985 JBrowse link
G SERAC1 serine active site containing 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:8,935,081...9,002,774
Ensembl chr 1:8,935,091...9,002,770 		JBrowse link
G STAR steroidogenic acute regulatory protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:48,377,597...48,385,398
Ensembl chr15:48,347,864...48,385,464 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 IEA
IBA		 (PMID:21873635) InterPro
GO_Central		 PMID:21873635 GO_REF:0000002 NCBI chr 2:116,235,821...116,257,143
Ensembl chr 2:116,235,816...116,257,041 		JBrowse link
G TSPO2 translocator protein 2 IEA Ensembl GO_REF:0000107 NCBI chr 7:36,347,027...36,352,497
Ensembl chr 7:36,347,060...36,352,495 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A ISO (PMID:10637304) UniProtKB PMID:10637304 NCBI chr 6:17,657,792...17,669,560 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484
G PCSK9 proprotein convertase subtilisin/kexin type 9 IEA Ensembl GO_REF:0000107 NCBI chr 6:157,388,370...157,409,620
Ensembl chr 6:157,388,372...157,409,604 		JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCP2 sterol carrier protein 2 ISO (PMID:15449949) UniProtKB PMID:15449949 NCBI chr 6:159,191,045...159,314,985 JBrowse link
G SCP2D1 SCP2 sterol binding domain containing 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:26,971,791...27,128,831
Ensembl chr17:26,980,152...26,984,768 		JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 IEA Ensembl GO_REF:0000107 NCBI chr 1:111,588,721...111,635,064
Ensembl chr 1:111,588,306...111,635,064 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:83,030,629...83,054,387
Ensembl chr 6:83,030,701...83,054,381 		JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor ISO (PMID:6299582) BHF-UCL PMID:6299582 NCBI chr 2:69,828,348...69,864,823
Ensembl chr 2:69,828,332...69,864,823 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 6:83,030,629...83,054,387
Ensembl chr 6:83,030,701...83,054,381 		JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:4413421|PMID:18948618) MGI PMID:18948618 MGI:4413421 NCBI chr 5:60,149,041...60,318,719
Ensembl chr 5:60,149,028...60,314,689 		JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:15238223)
(MGI:6478054|PMID:22748276)		 UniProtKB
UniProt		 PMID:15238223 PMID:22748276 MGI:6478054
G ARV1 ARV1 homolog, fatty acid homeostasis modulator ISO (PMID:20663892) UniProtKB PMID:20663892 NCBI chr14:59,396,958...59,409,008
Ensembl chr14:59,396,961...59,408,958 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit IEA Ensembl GO_REF:0000107 NCBI chr 1:44,156,771...44,186,224
Ensembl chr 1:44,156,778...44,186,194 		JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr10:52,224,367...52,408,928
Ensembl chr10:52,223,425...52,408,922 		JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chr 2:9,947,962...10,012,713
Ensembl chr 2:9,947,925...10,012,521 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16530
    localization 5930
      cellular localization 2796
        intracellular transport 1413
          intracellular lipid transport 33
            intracellular sterol transport 25
              intracellular cholesterol transport 25
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 4
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 8
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 16530
    localization 5930
      establishment of localization 4426
        transport 4265
          ion transport 3198
            anion transport 2454
              organic substance transport 2329
                lipid transport 449
                  sterol transport 109
                    cholesterol transport 95
                      intracellular cholesterol transport 25
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 4
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 8
                        vesicle-mediated cholesterol transport + 2
paths to the root