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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.


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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:31,057,694...31,117,984
Ensembl chr17:31,057,675...31,117,988
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr18:12,189,694...12,236,506
Ensembl chr18:12,189,692...12,236,400
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 IBA
IMP
ISO
(MGI:6201960|PMID:21873635)
(MGI:3763329|PMID:17018531)
GO_Central
HGNC-UCL
MGI
PMID:17018531 PMID:21873635 GO_REF:0000008 MGI:2154458 MGI:3763329 MGI:6201960 NCBI chr12:84,754,559...84,773,112
Ensembl chr12:84,754,562...84,773,152
JBrowse link
G Osbp oxysterol binding protein ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr19:11,965,844...11,994,114
Ensembl chr19:11,965,941...11,994,112
JBrowse link
G Osbpl2 oxysterol binding protein-like 2 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:180,116,318...180,162,682
Ensembl chr 2:180,119,306...180,162,680
JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:105,663,843...105,755,131
Ensembl chr 1:105,663,861...105,755,191
JBrowse link
G Scp2 sterol carrier protein 2, liver ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:108,043,830...108,144,971
Ensembl chr 4:108,043,839...108,144,998
JBrowse link
G Serac1 serine active site containing 1 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:6,040,571...6,079,789
Ensembl chr17:6,042,196...6,079,741
JBrowse link
G Snord60 small nucleolar RNA, C/D box 60 IMP (MGI:5554658|PMID:24174535) MGI PMID:24174535 MGI:5554658 NCBI chr17:24,528,476...24,528,553
Ensembl chr17:24,528,476...24,528,553
JBrowse link
G Star steroidogenic acute regulatory protein IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:25,808,474...25,815,982
Ensembl chr 8:25,806,555...25,815,982
JBrowse link
G Stard4 StAR-related lipid transfer (START) domain containing 4 IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr18:33,199,138...33,213,862
Ensembl chr18:33,199,355...33,213,862
JBrowse link
G Tspo2 translocator protein 2 IMP (MGI:6450299|PMID:32358067) UniProt PMID:32358067 MGI:6450299 NCBI chr17:48,447,942...48,451,564
Ensembl chr17:48,447,907...48,451,522
JBrowse link
G Vps4a vacuolar protein sorting 4A ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:107,031,269...107,045,760
Ensembl chr 8:107,031,222...107,045,755
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:106,442,334...106,464,325
Ensembl chr 4:106,442,329...106,464,329
JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2, liver IBA
ISO
(MGI:6201960|PMID:21873635) GO_Central
MGI
PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 4:108,043,830...108,144,971
Ensembl chr 4:108,043,839...108,144,998
JBrowse link
G Scp2d1 SCP2 sterol-binding domain containing 1 IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 2:144,823,666...144,824,415
Ensembl chr 2:144,823,656...144,824,415
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 IMP
ISO
(MGI:5446858|PMID:22848640) BHF-UCL
MGI
PMID:22848640 GO_REF:0000096 MGI:4834177 MGI:5446858 NCBI chr 9:69,453,683...69,491,792
Ensembl chr 9:69,453,620...69,491,795
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:134,741,554...134,768,032
Ensembl chr 4:134,741,554...134,768,024
JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:21,723,576...21,749,919
Ensembl chr 9:21,723,483...21,749,919
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:134,741,554...134,768,032
Ensembl chr 4:134,741,554...134,768,024
JBrowse link
G Lrp6 low density lipoprotein receptor-related protein 6 IMP
IBA
(MGI:4413421|PMID:18948618)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:18948618 PMID:21873635 MGI:4413421 MGI:6201960 NCBI chr 6:134,446,476...134,566,913
Ensembl chr 6:134,446,476...134,566,965
JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A (ABC1), member 2 ISO
IMP
(MGI:6478054|PMID:22748276) MGI
UniProt
PMID:22748276 GO_REF:0000096 MGI:4834177 MGI:6478054 NCBI chr 2:25,428,599...25,448,544
Ensembl chr 2:25,428,703...25,448,540
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 8:124,722,026...124,742,794
Ensembl chr 8:124,722,139...124,734,123
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit IMP
ISO
(MGI:4358633|PMID:19723497) MGI PMID:19723497 GO_REF:0000008 MGI:2154458 MGI:4358633 NCBI chr10:52,417,547...52,440,192
Ensembl chr10:52,417,547...52,440,183
JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:18,842,255...18,998,291
Ensembl chr 2:18,842,255...18,998,126
JBrowse link
G Syt7 synaptotagmin VII IDA (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chr19:10,388,802...10,453,181
Ensembl chr19:10,389,090...10,453,180
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23351
    localization 6246
      cellular localization 2874
        intracellular transport 1459
          intracellular lipid transport 34
            intracellular sterol transport 25
              intracellular cholesterol transport 25
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 4
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 8
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 23351
    localization 6246
      establishment of localization 4683
        transport 4523
          ion transport 3397
            anion transport 2648
              organic substance transport 2533
                lipid transport 450
                  sterol transport 99
                    cholesterol transport 97
                      intracellular cholesterol transport 25
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 4
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 8
                        vesicle-mediated cholesterol transport + 2
paths to the root