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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 ISO (PMID:10431236) BHF-UCL PMID:10431236 NCBI chr11:60,761,669...60,869,753
Ensembl chr11:60,761,655...60,890,496 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 IEA InterPro GO_REF:0000002 NCBI chr31:36,574,406...36,627,598
Ensembl chr31:36,553,380...36,620,043 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:64,764,941...64,802,507
Ensembl chr 7:64,760,121...64,802,902 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 ISS
IBA
IEA		 (PMID:21873635) UniProtKB
GO_Central
InterPro		 PMID:21873635 GO_REF:0000002 GO_REF:0000024 NCBI chr 8:47,641,185...47,650,543
Ensembl chr 8:47,628,077...47,650,576 		JBrowse link
G OSBP oxysterol binding protein IEA Ensembl GO_REF:0000107 NCBI chr18:37,159,511...37,191,720
Ensembl chr18:37,159,576...37,189,731 		JBrowse link
G RELCH RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr 1:14,573,377...14,683,795
Ensembl chr 1:14,579,381...14,683,555 		JBrowse link
G SCP2 sterol carrier protein 2 ISO (PMID:7642518) UniProt PMID:7642518 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014 		JBrowse link
G SERAC1 serine active site containing 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:47,599,802...47,651,034
Ensembl chr 1:47,578,472...47,669,494 		JBrowse link
G STAR steroidogenic acute regulatory protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr16:27,326,355...27,331,025
Ensembl chr16:27,326,355...27,331,025 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 IEA
IBA		 (PMID:21873635) InterPro
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000002 GO_REF:0000107 NCBI chr 3:1,154,358...1,171,248
Ensembl chr 3:1,154,358...1,170,469 		JBrowse link
G TSPO2 translocator protein 2 IMP (PMID:32358067) UniProt PMID:32358067 NCBI chr12:9,796,421...9,799,181
Ensembl chr12:9,795,739...9,799,178 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A ISO (PMID:10637304) UniProtKB PMID:10637304 NCBI chr 5:80,327,059...80,340,380 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 5:54,197,211...54,210,724 JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCP2 sterol carrier protein 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:55,860,053...55,971,657
Ensembl chr 5:55,860,549...55,964,014 		JBrowse link
G SCP2D1 SCP2 sterol binding domain containing 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr24:4,400,768...4,411,013
Ensembl chr24:4,400,097...4,401,447 		JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)		 BHF-UCL PMID:22848640 MGI:5446858 NCBI chr30:25,176,845...25,210,244
Ensembl chr30:25,115,842...25,218,281 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:74,340,272...74,363,929
Ensembl chr 2:74,341,036...74,364,162 		JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor ISO (PMID:6299582) BHF-UCL PMID:6299582 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:74,340,272...74,363,929
Ensembl chr 2:74,341,036...74,364,162 		JBrowse link
G LRP6 LDL receptor related protein 6 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr27:34,003,334...34,166,334
Ensembl chr27:34,003,539...34,161,437 		JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:15238223)
(MGI:6478054|PMID:22748276)		 UniProtKB
UniProt		 PMID:15238223 PMID:22748276 MGI:6478054 NCBI chr 9:48,610,906...48,630,932
Ensembl chr 9:48,613,996...48,629,857 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator ISO (PMID:20663892) UniProtKB PMID:20663892 NCBI chr 4:8,409,039...8,424,776
Ensembl chr 4:8,409,484...8,424,644 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit IEA Ensembl GO_REF:0000107 NCBI chr 1:57,866,760...57,895,505
Ensembl chr 1:57,866,879...57,893,077 		JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha IEA Ensembl GO_REF:0000107 NCBI chr 2:10,464,019...10,642,365
Ensembl chr 2:10,463,010...10,640,327 		JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chr18:54,863,072...54,926,121
Ensembl chr18:54,861,754...54,921,367 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16106
    localization 5990
      cellular localization 2839
        intracellular transport 1443
          intracellular lipid transport 31
            intracellular sterol transport 23
              intracellular cholesterol transport 23
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 4
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 8
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 16106
    localization 5990
      establishment of localization 4471
        transport 4310
          ion transport 3253
            anion transport 2487
              organic substance transport 2361
                lipid transport 441
                  sterol transport 112
                    cholesterol transport 99
                      intracellular cholesterol transport 23
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 4
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 8
                        vesicle-mediated cholesterol transport + 2
paths to the root