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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 ISO (PMID:10431236) BHF-UCL PMID:10431236 NCBI chrNW_004955419:21,553,863...21,681,626
Ensembl chrNW_004955419:21,553,835...21,681,619 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 ISO (PMID:15994327) BHF-UCL PMID:15994327 NCBI chrNW_004955407:39,410,262...39,459,383
Ensembl chrNW_004955407:39,410,262...39,459,383 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) UniProtKB PMID:9211849 PMID:27238017 PMID:28784760 NCBI chrNW_004955402:11,699,434...11,742,899
Ensembl chrNW_004955402:11,699,434...11,742,899 		JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 ISO (PMID:15937921), (PMID:27238017)
(MGI:3763329|PMID:17018531)
(PMID:19723497)
(PMID:17018531), (PMID:18823126)		 UniProtKB
HGNC-UCL
MGI
HGNC		 PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017 MGI:3763329 NCBI chrNW_004955523:1,010,976...1,021,048
Ensembl chrNW_004955523:1,010,976...1,021,144 		JBrowse link
G Osbp oxysterol binding protein ISO (PMID:29514919) UniProtKB PMID:29514919 NCBI chrNW_004955511:4,057,514...4,076,039
Ensembl chrNW_004955511:4,057,514...4,076,046 		JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing ISO (PMID:29514919) UniProtKB PMID:29514919 NCBI chrNW_004955402:46,114,835...46,226,330
Ensembl chrNW_004955402:46,115,066...46,224,752 		JBrowse link
G Scp2 sterol carrier protein 2 ISO (PMID:7642518) UniProt PMID:7642518 NCBI chrNW_004955464:6,097,241...6,224,287
Ensembl chrNW_004955464:6,094,758...6,224,287 		JBrowse link
G Serac1 serine active site containing 1 ISO (PMID:22683713) UniProtKB PMID:22683713 NCBI chrNW_004955439:4,234,440...4,291,947
Ensembl chrNW_004955439:4,234,382...4,291,941 		JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:14617579 RGD:4145640 NCBI chrNW_004955463:13,760,089...13,765,245
Ensembl chrNW_004955463:13,760,089...13,765,244 		JBrowse link
G Stard4 StAR related lipid transfer domain containing 4 ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004955418:3,637,390...3,652,054
Ensembl chrNW_004955418:3,638,399...3,648,402 		JBrowse link
G Tspo2 translocator protein 2 ISO (PMID:32358067)
(MGI:6450299|PMID:32358067)		 UniProt PMID:32358067 MGI:6450299 NCBI chrNW_004955437:7,714,107...7,715,796
Ensembl chrNW_004955437:7,714,107...7,715,796 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A ISO (PMID:10637304) UniProtKB PMID:10637304 NCBI chrNW_004955484:7,368,938...7,375,964 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004955464:4,424,583...4,439,805
Ensembl chrNW_004955464:4,425,435...4,439,842 		JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2 ISO (PMID:15449949) UniProtKB PMID:15449949 NCBI chrNW_004955464:6,097,241...6,224,287
Ensembl chrNW_004955464:6,094,758...6,224,287 		JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)		 BHF-UCL PMID:22848640 MGI:5446858 NCBI chrNW_004955450:14,545,586...14,574,161
Ensembl chrNW_004955450:14,512,381...14,574,696 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182 		JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor ISO (PMID:6299582) BHF-UCL PMID:6299582 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056 		JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182 		JBrowse link
G Lrp6 LDL receptor related protein 6 ISO (MGI:4413421|PMID:18948618) MGI PMID:18948618 MGI:4413421 NCBI chrNW_004955413:9,080,901...9,237,644
Ensembl chrNW_004955413:9,080,914...9,237,650 		JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 ISO (PMID:15238223)
(MGI:6478054|PMID:22748276)		 UniProtKB
UniProt		 PMID:15238223 PMID:22748276 MGI:6478054 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200 		JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator ISO (PMID:20663892) UniProtKB PMID:20663892 NCBI chrNW_004955492:7,669,956...7,683,293
Ensembl chrNW_004955492:7,672,746...7,683,728 		JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO (PMID:19723497)
(MGI:4358633|PMID:19723497)		 MGI PMID:19723497 MGI:4358633 NCBI chrNW_004955436:825,387...850,558
Ensembl chrNW_004955436:825,387...850,558 		JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO (PMID:29353240) UniProt PMID:29353240 NCBI chrNW_004955429:6,231,135...6,399,672
Ensembl chrNW_004955429:6,336,355...6,399,672 		JBrowse link
G Syt7 synaptotagmin 7 ISO (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chrNW_004955511:6,051,392...6,093,651
Ensembl chrNW_004955511:6,051,386...6,093,651 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11920
    localization 4771
      cellular localization 2345
        intracellular transport 1056
          intracellular lipid transport 27
            intracellular sterol transport 22
              intracellular cholesterol transport 22
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 3
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 7
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 11920
    localization 4771
      establishment of localization 3412
        transport 3253
          ion transport 2319
            anion transport 1769
              organic substance transport 1690
                lipid transport 335
                  sterol transport 87
                    cholesterol transport 87
                      intracellular cholesterol transport 22
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 3
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 7
                        vesicle-mediated cholesterol transport + 2
paths to the root