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ONTOLOGY REPORT - ANNOTATIONS

Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.

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intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 ISO (PMID:10431236) BHF-UCL PMID:10431236 NCBI chr 9:75,948,831...76,096,136
Ensembl chr 9:104,076,516...104,224,188 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 ISO (PMID:15994327) BHF-UCL PMID:15994327 NCBI chr21:28,534,697...28,619,590
Ensembl chr21:41,839,115...41,933,050 		JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) UniProtKB PMID:9211849 PMID:27238017 PMID:28784760 NCBI chr18:16,783,096...16,838,301
Ensembl chr18:20,409,040...20,463,623 		JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 ISO (PMID:15937921), (PMID:27238017)
(MGI:3763329|PMID:17018531)
(PMID:19723497)
(PMID:17018531), (PMID:18823126)		 UniProtKB
HGNC-UCL
MGI
HGNC		 PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017 MGI:3763329 NCBI chr14:55,033,129...55,046,564
Ensembl chr14:73,875,889...73,894,628 		JBrowse link
G OSBP oxysterol binding protein ISO (PMID:29514919) UniProtKB PMID:29514919 NCBI chr11:54,800,756...54,841,191
Ensembl chr11:58,252,925...58,291,154 		JBrowse link
G RELCH RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing ISO (PMID:29514919) UniProtKB PMID:29514919 NCBI chr18:55,557,276...55,677,161
Ensembl chr18:58,875,013...58,995,036 		JBrowse link
G SCP2 sterol carrier protein 2 ISO (PMID:7642518) UniProt PMID:7642518 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
G SERAC1 serine active site containing 1 ISO (PMID:22683713) UniProtKB PMID:22683713 NCBI chr 6:156,009,815...156,067,675
Ensembl chr 6:158,068,838...158,126,603 		JBrowse link
G STAR steroidogenic acute regulatory protein ISO RGD PMID:14617579 RGD:4145640 NCBI chr 8:37,446,334...37,454,102
Ensembl chr 8:34,623,201...34,629,544 		JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chr 5:106,855,990...106,873,384
Ensembl chr 5:112,657,516...112,675,165 		JBrowse link
G TSPO2 translocator protein 2 ISO (PMID:32358067)
(MGI:6450299|PMID:32358067)		 UniProt PMID:32358067 MGI:6450299 NCBI chr 6:40,630,564...40,633,028
Ensembl chr 6:41,939,481...41,941,328 		JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A ISO (PMID:10637304) UniProtKB PMID:10637304 NCBI chr16:49,685,827...49,699,542 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chr 1:54,323,036...54,355,397
Ensembl chr 1:55,911,016...55,936,456 		JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SCP2 sterol carrier protein 2 ISO (PMID:15449949) UniProtKB PMID:15449949 NCBI chr 1:52,195,491...52,324,227
Ensembl chr 1:53,797,254...53,924,939 		JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)		 BHF-UCL PMID:22848640 MGI:5446858 NCBI chr15:39,322,303...39,371,565
Ensembl chr15:57,625,425...57,674,250 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 1:24,809,535...24,852,394
Ensembl chr 1:25,878,358...25,903,336 		JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor ISO (PMID:6299582) BHF-UCL PMID:6299582 NCBI chr19:10,640,225...10,683,728
Ensembl chr19:11,357,311...11,396,791 		JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 1:24,809,535...24,852,394
Ensembl chr 1:25,878,358...25,903,336 		JBrowse link
G LRP6 LDL receptor related protein 6 ISO (MGI:4413421|PMID:18948618) MGI PMID:18948618 MGI:4413421 NCBI chr12:12,121,411...12,288,590
Ensembl chr12:12,508,108...12,657,973 		JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 ISO (PMID:15238223)
(MGI:6478054|PMID:22748276)		 UniProtKB
UniProt		 PMID:15238223 PMID:22748276 MGI:6478054 NCBI chr 9:108,067,633...108,089,742
Ensembl chr 9:137,036,696...137,057,776 		JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator ISO (PMID:20663892) UniProtKB PMID:20663892 NCBI chr 1:206,527,777...206,549,606
Ensembl chr 1:211,554,553...211,576,484 		JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit ISO (PMID:19723497)
(MGI:4358633|PMID:19723497)		 MGI PMID:19723497 MGI:4358633 NCBI chr 6:115,486,422...115,521,317 JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha ISO (PMID:29353240) UniProt PMID:29353240 NCBI chr10:22,691,355...22,870,628 JBrowse link
G SYT7 synaptotagmin 7 ISO (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chr11:56,814,694...56,880,439
Ensembl chr11:60,175,403...60,242,375 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12593
    localization 4951
      cellular localization 2389
        intracellular transport 1074
          intracellular lipid transport 27
            intracellular sterol transport 22
              intracellular cholesterol transport 22
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 3
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 7
                vesicle-mediated cholesterol transport + 2
Path 2
Term Annotations click to browse term
  biological_process 12593
    localization 4951
      establishment of localization 3534
        transport 3371
          ion transport 2403
            anion transport 1827
              organic substance transport 1747
                lipid transport 352
                  sterol transport 92
                    cholesterol transport 91
                      intracellular cholesterol transport 22
                        negative regulation of intracellular cholesterol transport + 2
                        positive regulation of intracellular cholesterol transport + 3
                        receptor-mediated endocytosis involved in cholesterol transport + 6
                        regulation of intracellular cholesterol transport + 7
                        vesicle-mediated cholesterol transport + 2
paths to the root