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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular cholesterol transport
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Accession:GO:0032367 term browser browse the term
Definition:The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.



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intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:10431236) RGD PMID:10431236 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) RGD PMID:9211849 PMID:27238017 PMID:28784760 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:Q96E22 (PMID:19723497)
(PMID:15937921), (PMID:17018531), (PMID:18823126), (PMID:27238017)
(MGI:3763329|PMID:17018531)
RGD PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017 More... MGI:3763329, RGD:13792537 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
JBrowse link
G Osbp oxysterol binding protein involved_in ISO (PMID:29514919) RGD PMID:29514919 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
JBrowse link
G Osbpl2 oxysterol binding protein-like 2 involved_in ISO
IEA
(PMID:30581148)
GO_REF:0000107
RGD
Ensembl
PMID:30581148 GO_REF:0000107 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219
JBrowse link
G Rab11a RAB11a, member RAS oncogene family involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing involved_in ISO (PMID:29514919) RGD PMID:29514919 NCBI chr13:21,806,972...21,902,807
Ensembl chr13:21,806,972...21,902,807
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO
ISS
(PMID:7642518)
GO_REF:0000024
RGD
UniProt
PMID:7642518 GO_REF:0000024 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Serac1 serine active site containing 1 involved_in ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727
JBrowse link
G Star steroidogenic acute regulatory protein involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:14617579 PMID:21873635 RGD:4145640, RGD:13792537 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:18403318)
RGD PMID:18403318 PMID:21873635 RGD:13792537 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Tspo2 translocator protein 2 involved_in ISO (PMID:32358067)
(MGI:6450299|PMID:32358067)
RGD PMID:32358067 MGI:6450299 NCBI chr 9:12,544,615...12,548,563
Ensembl chr 9:12,545,015...12,548,573
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:10637304) RGD PMID:10637304 NCBI chr19:34,934,999...34,948,267
Ensembl chr19:34,934,961...34,948,887
JBrowse link
endosome to lysosome transport of low-density lipoprotein particle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISS
ISO
GO_REF:0000024
(PMID:21802320)
UniProt
RGD
PMID:21802320 GO_REF:0000024 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596
JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO
IEA
(MGI:5691857|PMID:25144390)
GO_REF:0000107
RGD
Ensembl
PMID:25144390 GO_REF:0000107 MGI:5691857 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scp2 sterol carrier protein 2 involved_in IBA
ISO
PMID:21873635
(PMID:15449949)
RGD PMID:15449949 PMID:21873635 RGD:13792537 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Scp2d1 SCP2 sterol-binding domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:132,201,979...132,202,729
Ensembl chr 3:132,200,744...132,212,725
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
RGD PMID:22848640 MGI:5446858 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IEA
(PMID:6299582)
GO_REF:0000107
RGD
Ensembl
PMID:6299582 GO_REF:0000107 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:4123883 (MGI:4413421|PMID:18948618)
RGD PMID:18948618 PMID:21873635 PMID:21873635 MGI:4413421, RGD:13792537, RGD:13792537 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6478054|PMID:22748276)
(PMID:15238223)
UniProt
RGD
PMID:15238223 PMID:22748276 GO_REF:0000024 MGI:6478054 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in ISO (PMID:20663892) RGD PMID:20663892 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit acts_upstream_of_or_within ISO (MGI:4358633|PMID:19723497)
UniProtKB:P61916 (PMID:19723497)
RGD PMID:19723497 MGI:4358633 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISS
ISO
GO_REF:0000024
(PMID:29353240)
UniProt
RGD
PMID:29353240 GO_REF:0000024 NCBI chr17:81,496,669...81,668,180 JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5645834|PMID:25860611)
UniProt
RGD
PMID:25860611 GO_REF:0000024 MGI:5645834 NCBI chr 1:207,031,369...207,093,787
Ensembl chr 1:207,031,592...207,089,026
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    localization 6488
      cellular localization 3040
        intracellular transport 1604
          intracellular lipid transport 37
            intracellular sterol transport 27
              intracellular cholesterol transport 27
                negative regulation of intracellular cholesterol transport + 2
                positive regulation of intracellular cholesterol transport + 4
                receptor-mediated endocytosis involved in cholesterol transport + 6
                regulation of intracellular cholesterol transport + 8
                vesicle-mediated cholesterol transport + 4
Path 2
Term Annotations click to browse term
  biological_process 19497
    localization 6488
      establishment of localization 4887
        transport 4725
          organic substance transport 2506
            lipid transport 423
              sterol transport 125
                cholesterol transport 110
                  intracellular cholesterol transport 27
                    negative regulation of intracellular cholesterol transport + 2
                    positive regulation of intracellular cholesterol transport + 4
                    receptor-mediated endocytosis involved in cholesterol transport + 6
                    regulation of intracellular cholesterol transport + 8
                    vesicle-mediated cholesterol transport + 4
paths to the root