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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular sterol transport
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Accession:GO:0032366 term browser browse the term
Definition:The directed movement of sterols within cells.



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intracellular sterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in IBA
IEA
(PMID:21873635) GO_Central
InterPro
GO_Central
InterPro
PMID:21873635 GO_REF:0000002 NCBI chr 1:230,979,082...231,000,733
Ensembl chr 1:230,978,981...231,000,733
JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 involved_in IDA (PMID:17018531) HGNC-UCL
HGNC-UCL
PMID:17018531 NCBI chr14:74,479,935...74,493,512
Ensembl chr14:74,476,192...74,494,177
JBrowse link
cholesterol ester hydrolysis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CES1 carboxylesterase 1 involved_in TAS (PMID:11015575) BHF-UCL
BHF-UCL
PMID:11015575 NCBI chr16:55,802,851...55,833,127
Ensembl chr16:55,802,851...55,833,337
JBrowse link
endosome to lysosome transport of low-density lipoprotein particle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ARL8B ADP ribosylation factor like GTPase 8B involved_in IMP (PMID:21802320) UniProt
UniProt
PMID:21802320 NCBI chr 3:5,122,292...5,180,911
Ensembl chr 3:5,122,249...5,180,911
JBrowse link
G TPCN2 two pore segment channel 2 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr11:69,048,932...69,090,597
Ensembl chr11:69,048,932...69,136,316
JBrowse link
intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA1 ATP binding cassette subfamily A member 1 involved_in IMP (PMID:10431236) BHF-UCL
BHF-UCL
PMID:10431236 NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 involved_in IEA
IMP
(PMID:15994327) InterPro
BHF-UCL
InterPro
BHF-UCL
PMID:15994327 GO_REF:0000002 NCBI chr21:42,199,689...42,304,387
Ensembl chr21:42,199,689...42,297,244
JBrowse link
G NPC1 NPC intracellular cholesterol transporter 1 involved_in IMP (PMID:27238017), (PMID:28784760), (PMID:9211849) UniProt
UniProt
PMID:9211849 PMID:27238017 PMID:28784760 NCBI chr18:23,506,184...23,586,506
Ensembl chr18:23,506,184...23,586,506
JBrowse link
G NPC2 NPC intracellular cholesterol transporter 2 involved_in
acts_upstream_of_or_within
IMP
IEA
IGI
IDA
IBA
(PMID:15937921), (PMID:27238017)
(PMID:19723497)
(PMID:17018531), (PMID:18823126)
(PMID:21873635)
UniProt
InterPro
MGI
UniProt
Ensembl
HGNC-UCL
GO_Central
MGI
GO_Central
InterPro
HGNC-UCL
PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:21873635 More... GO_REF:0000002 GO_REF:0000107 NCBI chr14:74,479,935...74,493,512
Ensembl chr14:74,476,192...74,494,177
JBrowse link
G OSBP oxysterol binding protein involved_in IMP (PMID:29514919) UniProt
UniProt
PMID:29514919 NCBI chr11:59,574,398...59,615,774
Ensembl chr11:59,574,398...59,615,774
JBrowse link
G OSBPL2 oxysterol binding protein like 2 involved_in IMP (PMID:30581148) UniProt
UniProt
PMID:30581148 NCBI chr20:62,238,521...62,296,183
Ensembl chr20:62,231,922...62,296,213
JBrowse link
G RELCH RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing involved_in IDA
IEA
(PMID:29514919) UniProt
InterPro
UniProt
InterPro
PMID:29514919 GO_REF:0000002 NCBI chr18:62,187,255...62,310,249
Ensembl chr18:62,187,255...62,310,249
JBrowse link
G SCP2 sterol carrier protein 2 involved_in IMP (PMID:7642518) UniProt
UniProt
PMID:7642518 NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
JBrowse link
G SERAC1 serine active site containing 1 involved_in IMP (PMID:22683713) UniProt
UniProt
PMID:22683713 NCBI chr 6:158,109,515...158,168,270
Ensembl chr 6:158,109,519...158,168,280
JBrowse link
G SNORD60 small nucleolar RNA, C/D box 60 acts_upstream_of_or_within ISO (MGI:5554658|PMID:24174535) MGI PMID:24174535 MGI:5554658 NCBI chr16:2,155,023...2,155,105
Ensembl chr16:2,155,023...2,155,105
JBrowse link
G STAR steroidogenic acute regulatory protein involved_in IBA
ISO
(PMID:21873635) GO_Central
GO_Central
RGD
PMID:14617579 PMID:21873635 RGD:4145640 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STARD4 StAR related lipid transfer domain containing 4 involved_in IDA
IEA
IBA
(PMID:18403318)
(PMID:21873635)
BHF-UCL
BHF-UCL
InterPro
GO_Central
GO_Central
InterPro
PMID:18403318 PMID:21873635 GO_REF:0000002 NCBI chr 5:111,491,422...111,512,567
Ensembl chr 5:111,496,033...111,512,590
JBrowse link
G TSPO2 translocator protein 2 involved_in ISS
IEA
UniProt
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 6:41,041,344...41,044,337
Ensembl chr 6:41,042,467...41,044,337
JBrowse link
G VPS4A vacuolar protein sorting 4 homolog A involved_in IMP (PMID:10637304) UniProt
UniProt
PMID:10637304 NCBI chr16:69,311,350...69,326,939
Ensembl chr16:69,311,350...69,326,939
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL
ARUK-UCL
PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 acts_upstream_of IDA (PMID:21810484) ARUK-UCL
ARUK-UCL
PMID:21810484 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915
JBrowse link
G PCSK9 proprotein convertase subtilisin/kexin type 9 involved_in IDA (PMID:22848640) BHF-UCL
BHF-UCL
PMID:22848640 NCBI chr 1:55,039,548...55,064,852
Ensembl chr 1:55,039,447...55,064,852
JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (PMID:16530456) AgBase PMID:16530456 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G SCP2 sterol carrier protein 2 involved_in IBA
NAS
IDA
(PMID:21873635)
(PMID:1703300)
(PMID:15449949)
GO_Central
GO_Central
UniProt
UniProt
PMID:1703300 PMID:15449949 PMID:21873635 NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698
JBrowse link
G SCP2D1 SCP2 sterol binding domain containing 1 involved_in IBA (PMID:21873635) GO_Central
GO_Central
PMID:21873635 NCBI chr20:18,813,783...18,814,378
Ensembl chr20:18,813,783...18,814,378
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 involved_in IDA (PMID:22848640) BHF-UCL
BHF-UCL
PMID:22848640 NCBI chr15:60,347,151...60,398,025
Ensembl chr15:60,347,134...60,402,883
JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IMP (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL
BHF-UCL
PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 1:25,543,588...25,590,400
Ensembl chr 1:25,543,606...25,568,886
JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LDLR low density lipoprotein receptor involved_in IMP
IBA
(PMID:6299582)
(PMID:21873635)
BHF-UCL
BHF-UCL
GO_Central
GO_Central
PMID:6299582 PMID:21873635 NCBI chr19:11,089,432...11,133,820
Ensembl chr19:11,089,462...11,133,820
JBrowse link
G LDLRAP1 low density lipoprotein receptor adaptor protein 1 involved_in IMP (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL
BHF-UCL
PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 1:25,543,588...25,590,400
Ensembl chr 1:25,543,606...25,568,886
JBrowse link
G LRP6 LDL receptor related protein 6 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:4413421|PMID:18948618)
(PMID:21873635)
MGI
GO_Central
GO_Central
PMID:18948618 PMID:21873635 MGI:4413421 NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044
JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA2 ATP binding cassette subfamily A member 2 involved_in IMP
ISS
(PMID:15238223) UniProt
UniProt
PMID:15238223 GO_REF:0000024 NCBI chr 9:137,007,234...137,028,922
Ensembl chr 9:137,007,234...137,028,915
JBrowse link
G ARV1 ARV1 homolog, fatty acid homeostasis modulator involved_in IMP (PMID:20663892) UniProt
UniProt
PMID:20663892 NCBI chr 1:230,979,082...231,000,733
Ensembl chr 1:230,978,981...231,000,733
JBrowse link
G NUS1 NUS1 dehydrodolichyl diphosphate synthase subunit acts_upstream_of_or_within
involved_in
IGI
IEA
(PMID:19723497) MGI
Ensembl
MGI
PMID:19723497 GO_REF:0000107 NCBI chr 6:117,675,469...117,710,727
Ensembl chr 6:117,675,469...117,710,727
JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PIP4K2A phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in IMP (PMID:29353240) UniProt
UniProt
PMID:29353240 NCBI chr10:22,534,854...22,714,578
Ensembl chr10:22,534,854...22,714,578
JBrowse link
G SYT7 synaptotagmin 7 involved_in ISS UniProt
UniProt
GO_REF:0000024 NCBI chr11:61,513,714...61,588,404
Ensembl chr11:61,513,714...61,581,148
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18659
    localization 6715
      cellular localization 3180
        intracellular transport 1734
          intracellular lipid transport 44
            intracellular sterol transport 29
              intracellular cholesterol transport + 29
              negative regulation of intracellular sterol transport + 2
              positive regulation of intracellular sterol transport + 5
              regulation of intracellular sterol transport + 9
Path 2
Term Annotations click to browse term
  biological_process 18659
    localization 6715
      establishment of localization 5092
        transport 4931
          organic substance transport 2737
            organic hydroxy compound transport 327
              sterol transport 125
                intracellular sterol transport 29
                  intracellular cholesterol transport + 29
                  negative regulation of intracellular sterol transport + 2
                  positive regulation of intracellular sterol transport + 5
                  regulation of intracellular sterol transport + 9
paths to the root