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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular sterol transport
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Accession:GO:0032366 term browser browse the term
Definition:The directed movement of sterols within cells.


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intracellular sterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npc2 NPC intracellular cholesterol transporter 2 involved_in ISO (PMID:17018531) HGNC-UCL PMID:17018531 NCBI chrNW_004955523:1,010,976...1,021,048
Ensembl chrNW_004955523:1,010,976...1,021,144
JBrowse link
endosome to lysosome transport of low-density lipoprotein particle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP ribosylation factor like GTPase 8B involved_in ISO (PMID:21802320) UniProt PMID:21802320 NCBI chrNW_004955421:8,231,337...8,276,907
Ensembl chrNW_004955421:8,231,582...8,276,907
JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO (MGI:5691857|PMID:25144390) UniProt PMID:25144390 MGI:5691857 NCBI chrNW_004955422:16,899,730...16,923,962 JBrowse link
intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:10431236) BHF-UCL PMID:10431236 NCBI chrNW_004955419:21,553,863...21,681,626
Ensembl chrNW_004955419:21,553,835...21,681,619
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) BHF-UCL PMID:15994327 NCBI chrNW_004955407:39,410,262...39,459,383
Ensembl chrNW_004955407:39,410,262...39,459,383
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) UniProt PMID:9211849 PMID:27238017 PMID:28784760 NCBI chrNW_004955402:11,699,434...11,742,899
Ensembl chrNW_004955402:11,699,434...11,742,899
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 involved_in
acts_upstream_of_or_within
ISO (PMID:15937921), (PMID:27238017)
(PMID:19723497)
(MGI:3763329|PMID:17018531)
(PMID:17018531), (PMID:18823126)
UniProt
MGI
HGNC-UCL
PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017 MGI:3763329 NCBI chrNW_004955523:1,010,976...1,021,048
Ensembl chrNW_004955523:1,010,976...1,021,144
JBrowse link
G Osbp oxysterol binding protein involved_in ISO (PMID:29514919) UniProt PMID:29514919 NCBI chrNW_004955511:4,057,514...4,076,039
Ensembl chrNW_004955511:4,057,514...4,076,046
JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing involved_in ISO (PMID:29514919) UniProt PMID:29514919 NCBI chrNW_004955402:46,114,835...46,226,330
Ensembl chrNW_004955402:46,115,066...46,224,752
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:7642518) UniProt PMID:7642518 NCBI chrNW_004955464:6,097,241...6,224,287
Ensembl chrNW_004955464:6,094,758...6,224,287
JBrowse link
G Serac1 serine active site containing 1 involved_in ISO (PMID:22683713) UniProt PMID:22683713 NCBI chrNW_004955439:4,234,440...4,291,947
Ensembl chrNW_004955439:4,234,382...4,291,941
JBrowse link
G Star steroidogenic acute regulatory protein ISO RGD PMID:14617579 RGD:4145640 NCBI chrNW_004955463:13,760,089...13,765,245
Ensembl chrNW_004955463:13,760,089...13,765,244
JBrowse link
G Stard4 StAR related lipid transfer domain containing 4 involved_in ISO (PMID:18403318) BHF-UCL PMID:18403318 NCBI chrNW_004955418:3,637,390...3,652,054
Ensembl chrNW_004955418:3,638,399...3,648,402
JBrowse link
G Tspo2 translocator protein 2 involved_in ISO (PMID:32358067)
(MGI:6450299|PMID:32358067)
UniProt PMID:32358067 MGI:6450299 NCBI chrNW_004955437:7,714,107...7,715,796
Ensembl chrNW_004955437:7,714,107...7,715,796
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:10637304) UniProt PMID:10637304 NCBI chrNW_004955484:7,368,938...7,375,964 JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) ARUK-UCL PMID:21810484 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) BHF-UCL PMID:22848640 NCBI chrNW_004955464:4,424,583...4,439,805
Ensembl chrNW_004955464:4,425,435...4,439,842
JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator activated receptor gamma involved_in ISO (PMID:16530456) AgBase PMID:16530456 NCBI chrNW_004955429:14,814,690...14,936,869
Ensembl chrNW_004955429:14,873,908...14,937,387
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:15449949) UniProt PMID:15449949 NCBI chrNW_004955464:6,097,241...6,224,287
Ensembl chrNW_004955464:6,094,758...6,224,287
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
BHF-UCL PMID:22848640 MGI:5446858 NCBI chrNW_004955450:14,545,586...14,574,161
Ensembl chrNW_004955450:14,512,381...14,574,696
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182
JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO (PMID:6299582) BHF-UCL PMID:6299582 NCBI chrNW_004955495:2,114,702...2,135,584
Ensembl chrNW_004955495:2,114,434...2,138,056
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) BHF-UCL PMID:12417523 PMID:12464675 PMID:15166224 NCBI chrNW_004955452:5,081,919...5,102,349
Ensembl chrNW_004955452:5,081,556...5,095,182
JBrowse link
G Lrp6 LDL receptor related protein 6 acts_upstream_of_or_within ISO (MGI:4413421|PMID:18948618) MGI PMID:18948618 MGI:4413421 NCBI chrNW_004955413:9,080,901...9,237,644
Ensembl chrNW_004955413:9,080,914...9,237,650
JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISO (PMID:15238223)
(MGI:6478054|PMID:22748276)
UniProt PMID:15238223 PMID:22748276 MGI:6478054 NCBI chrNW_004955513:5,035,879...5,051,140
Ensembl chrNW_004955513:5,033,771...5,051,200
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in ISO (PMID:20663892) UniProt PMID:20663892 NCBI chrNW_004955492:7,669,956...7,683,293
Ensembl chrNW_004955492:7,672,746...7,683,728
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit acts_upstream_of_or_within ISO (MGI:4358633|PMID:19723497)
(PMID:19723497)
MGI PMID:19723497 MGI:4358633 NCBI chrNW_004955436:825,387...850,558
Ensembl chrNW_004955436:825,387...850,558
JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISO (PMID:29353240) UniProt PMID:29353240 NCBI chrNW_004955429:6,231,135...6,399,672
Ensembl chrNW_004955429:6,336,355...6,399,672
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISO (MGI:5645834|PMID:25860611) UniProt PMID:25860611 MGI:5645834 NCBI chrNW_004955511:6,051,392...6,093,651
Ensembl chrNW_004955511:6,051,386...6,093,651
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12107
    localization 4900
      cellular localization 2431
        intracellular transport 1149
          intracellular lipid transport 33
            intracellular sterol transport 25
              intracellular cholesterol transport + 25
              negative regulation of intracellular sterol transport + 2
              positive regulation of intracellular sterol transport + 4
              regulation of intracellular sterol transport + 8
Path 2
Term Annotations click to browse term
  biological_process 12107
    localization 4900
      establishment of localization 3495
        transport 3337
          organic substance transport 1686
            organic hydroxy compound transport 247
              sterol transport 94
                intracellular sterol transport 25
                  intracellular cholesterol transport + 25
                  negative regulation of intracellular sterol transport + 2
                  positive regulation of intracellular sterol transport + 4
                  regulation of intracellular sterol transport + 8
paths to the root