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ONTOLOGY REPORT - ANNOTATIONS


Term:intracellular sterol transport
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Accession:GO:0032366 term browser browse the term
Definition:The directed movement of sterols within cells.



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intracellular sterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 involved_in ISO (PMID:17018531) RGD PMID:17018531 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
JBrowse link
endosome to lysosome transport of low-density lipoprotein particle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arl8b ADP-ribosylation factor like GTPase 8B involved_in ISS
ISO
GO_REF:0000024
(PMID:21802320)
UniProt
RGD
PMID:21802320 GO_REF:0000024 NCBI chr 4:141,748,634...141,792,605
Ensembl chr 4:141,748,587...141,792,596
JBrowse link
G Tpcn2 two pore segment channel 2 involved_in ISO
IEA
(MGI:5691857|PMID:25144390)
GO_REF:0000107
RGD
Ensembl
PMID:25144390 GO_REF:0000107 MGI:5691857 NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
JBrowse link
intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 involved_in ISO (PMID:10431236) RGD PMID:10431236 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 involved_in ISO (PMID:15994327) RGD PMID:15994327 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G LOC120095400 small nucleolar RNA SNORD60 acts_upstream_of_or_within ISO (MGI:5554658|PMID:24174535) RGD PMID:24174535 MGI:5554658 NCBI chr10:13,552,773...13,552,855
Ensembl chr10:13,552,773...13,552,855
JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 involved_in ISO (PMID:27238017), (PMID:28784760), (PMID:9211849) RGD PMID:9211849 PMID:27238017 PMID:28784760 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
UniProtKB:Q96E22 (PMID:19723497)
(PMID:15937921), (PMID:17018531), (PMID:18823126), (PMID:27238017)
(MGI:3763329|PMID:17018531)
RGD PMID:15937921 PMID:17018531 PMID:18823126 PMID:19723497 PMID:27238017 More... MGI:3763329, RGD:13792537 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
JBrowse link
G Osbp oxysterol binding protein involved_in ISO (PMID:29514919) RGD PMID:29514919 NCBI chr 1:208,888,697...208,918,511
Ensembl chr 1:208,887,895...208,918,506
JBrowse link
G Osbpl2 oxysterol binding protein-like 2 involved_in ISO
IEA
(PMID:30581148)
GO_REF:0000107
RGD
Ensembl
PMID:30581148 GO_REF:0000107 NCBI chr 3:167,210,945...167,256,219
Ensembl chr 3:167,210,832...167,256,219
JBrowse link
G Rab11a RAB11a, member RAS oncogene family involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
JBrowse link
G Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing involved_in ISO (PMID:29514919) RGD PMID:29514919 NCBI chr13:21,806,972...21,902,807
Ensembl chr13:21,806,972...21,902,807
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO
ISS
(PMID:7642518)
GO_REF:0000024
RGD
UniProt
PMID:7642518 GO_REF:0000024 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Serac1 serine active site containing 1 involved_in ISO (PMID:22683713) RGD PMID:22683713 NCBI chr 1:46,620,741...46,656,801
Ensembl chr 1:46,620,498...46,656,727
JBrowse link
G Star steroidogenic acute regulatory protein involved_in IEP
IBA
PMID:21873635 RGD
GO_Central
PMID:14617579 PMID:21873635 RGD:4145640, RGD:13792537 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link
G Stard4 StAR-related lipid transfer domain containing 4 involved_in IBA
ISO
PMID:21873635
(PMID:18403318)
RGD PMID:18403318 PMID:21873635 RGD:13792537 NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024
JBrowse link
G Tspo2 translocator protein 2 involved_in ISO (PMID:32358067)
(MGI:6450299|PMID:32358067)
RGD PMID:32358067 MGI:6450299 NCBI chr 9:12,544,615...12,548,563
Ensembl chr 9:12,545,015...12,548,573
JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO (PMID:10637304) RGD PMID:10637304 NCBI chr19:34,934,999...34,948,267
Ensembl chr19:34,934,961...34,948,887
JBrowse link
negative regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of ISO (PMID:21810484) RGD PMID:21810484 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
negative regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 acts_upstream_of
involved_in
ISO
IEA
(PMID:21810484)
GO_REF:0000107
RGD
Ensembl
PMID:21810484 GO_REF:0000107 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Pcsk9 proprotein convertase subtilisin/kexin type 9 involved_in ISO (PMID:22848640) RGD PMID:22848640 NCBI chr 5:121,211,278...121,233,688
Ensembl chr 5:121,211,278...121,233,688
JBrowse link
positive regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator-activated receptor gamma involved_in ISO (PMID:16530456) RGD PMID:16530456 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Scp2 sterol carrier protein 2 involved_in IBA
ISO
PMID:21873635
(PMID:15449949)
RGD PMID:15449949 PMID:21873635 RGD:13792537 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Scp2d1 SCP2 sterol-binding domain containing 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:132,201,979...132,202,729
Ensembl chr 3:132,200,744...132,212,725
JBrowse link
positive regulation of receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa2 annexin A2 involved_in ISO (PMID:22848640)
(MGI:5446858|PMID:22848640)
RGD PMID:22848640 MGI:5446858 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
receptor-mediated endocytosis involved in cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldlr low density lipoprotein receptor involved_in ISO
IBA
IEA
(PMID:6299582)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:6299582 PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Ldlrap1 low density lipoprotein receptor adaptor protein 1 involved_in ISO (PMID:12417523), (PMID:12464675), (PMID:15166224) RGD PMID:12417523 PMID:12464675 PMID:15166224 NCBI chr 5:146,955,607...146,978,601
Ensembl chr 5:146,955,607...146,978,601
JBrowse link
G Lrp6 LDL receptor related protein 6 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:4123883 (MGI:4413421|PMID:18948618)
RGD PMID:18948618 PMID:21873635 PMID:21873635 MGI:4413421, RGD:13792537, RGD:13792537 NCBI chr 4:167,266,581...167,400,155
Ensembl chr 4:167,270,353...167,400,497
JBrowse link
regulation of intracellular cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP binding cassette subfamily A member 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6478054|PMID:22748276)
(PMID:15238223)
UniProt
RGD
PMID:15238223 PMID:22748276 GO_REF:0000024 MGI:6478054 NCBI chr 3:8,244,515...8,264,545
Ensembl chr 3:8,244,639...8,264,537
JBrowse link
G Arv1 ARV1 homolog, fatty acid homeostasis modulator involved_in ISO (PMID:20663892) RGD PMID:20663892 NCBI chr19:52,692,337...52,704,156
Ensembl chr19:52,692,337...52,704,156
JBrowse link
G Nus1 NUS1 dehydrodolichyl diphosphate synthase subunit acts_upstream_of_or_within ISO (MGI:4358633|PMID:19723497)
UniProtKB:P61916 (PMID:19723497)
RGD PMID:19723497 MGI:4358633 NCBI chr20:31,811,817...31,838,562
Ensembl chr20:31,811,817...31,838,561
JBrowse link
vesicle-mediated cholesterol transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07028769.1 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:29353240)
UniProt
Ensembl
RGD
PMID:29353240 GO_REF:0000024 GO_REF:0000107 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029
JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO
GO_REF:0000024
(MGI:5645834|PMID:25860611)
UniProt
RGD
PMID:25860611 GO_REF:0000024 MGI:5645834 NCBI chr 1:207,031,369...207,093,787
Ensembl chr 1:207,031,592...207,089,026
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      cellular localization 3075
        intracellular transport 1625
          intracellular lipid transport 40
            intracellular sterol transport 30
              intracellular cholesterol transport + 30
              negative regulation of intracellular sterol transport + 2
              positive regulation of intracellular sterol transport + 5
              regulation of intracellular sterol transport + 9
Path 2
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      establishment of localization 4941
        transport 4779
          organic substance transport 2540
            organic hydroxy compound transport 315
              sterol transport 127
                intracellular sterol transport 30
                  intracellular cholesterol transport + 30
                  negative regulation of intracellular sterol transport + 2
                  positive regulation of intracellular sterol transport + 5
                  regulation of intracellular sterol transport + 9
paths to the root