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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone biosynthetic process
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Accession:GO:0032342 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.



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aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in IMP
IEA
ISO
PMID:19342457
GO_REF:0000107
(PMID:19342457)
Ensembl
RGD
PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
JBrowse link
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 involved_in IMP
IEA
IBA
PMID:19342457
GO_REF:0000118
GO_REF:0000033
TreeGrafter
GO_Central
PMID:19342457 GO_REF:0000033 GO_REF:0000118, RGD:4891166 NCBI chr 7:106,772,597...106,780,536
Ensembl chr 7:106,718,274...106,779,278
JBrowse link
G Cyp11b1-ps1 cytochrome P450, family 11, subfamily b, polypeptide 1, pseudogene 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:106,718,410...106,724,483 JBrowse link
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 involved_in IDA
IEA
IBA
ISO
GO_REF:0000118
GO_REF:0000033
(PMID:19342457), (PMID:2256920)
TreeGrafter
GO_Central
RGD
PMID:2256920 PMID:19342457 PMID:11832364 GO_REF:0000033 GO_REF:0000118, RGD:727991 NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004
JBrowse link
G Cyp11b2l1 cytochrome P450, family 11, subfamily b, polypeptide 2 like 1 involved_in IEA GO_REF:0000118 TreeGrafter GO_REF:0000118 NCBI chr 7:106,724,638...106,751,822
Ensembl chr 7:106,718,274...106,779,278
JBrowse link
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 involved_in
acts_upstream_of_or_within
ISO
IEA
(PMID:1741400), (PMID:19342457), (PMID:2256920), (PMID:23322723)
GO_REF:0000118
(MGI:50073|PMID:1686470), (MGI:80407|PMID:8645611)
RGD
TreeGrafter
PMID:1686470 PMID:1741400 PMID:2256920 PMID:8645611 PMID:19342457 More... GO_REF:0000118 MGI:50073 MGI:80407 NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19584291)
Ensembl
RGD
PMID:19584291 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) RGD PMID:16527843 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Dab2 DAB adaptor protein 2 IDA RGD PMID:17303656 RGD:7243836 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476
JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO
ISS
(PMID:29403011)
GO_REF:0000024
RGD
UniProt
PMID:29403011 GO_REF:0000024 NCBI chr11:80,197,741...80,211,657
Ensembl chr11:80,198,153...80,211,657
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20325
    cellular process 18797
      C21-steroid hormone metabolic process 52
        C21-steroid hormone biosynthetic process 29
          aldosterone biosynthetic process 14
            negative regulation of aldosterone biosynthetic process 4
            positive regulation of aldosterone biosynthetic process 3
            regulation of aldosterone biosynthetic process + 8
Path 2
Term Annotations click to browse term
  biological_process 20325
    metabolic process 11737
      organic substance metabolic process 11231
        organic cyclic compound metabolic process 6233
          steroid metabolic process 366
            steroid biosynthetic process 186
              steroid hormone biosynthetic process 47
                C21-steroid hormone biosynthetic process 29
                  aldosterone biosynthetic process 14
                    negative regulation of aldosterone biosynthetic process 4
                    positive regulation of aldosterone biosynthetic process 3
                    regulation of aldosterone biosynthetic process + 8
paths to the root