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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone metabolic process
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Accession:GO:0032341 term browser browse the term
Definition:The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
Synonyms:exact_synonym: aldosterone metabolism


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aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ednrb endothelin receptor type B involved_in ISO (MGI:3692691|PMID:16868309) MGI PMID:16868309 MGI:3692691 NCBI chrNW_004955404:29,394,253...29,425,358
Ensembl chrNW_004955404:29,394,164...29,425,358
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta acts_upstream_of_or_within ISO (MGI:6478095|PMID:28567665) MGI PMID:28567665 MGI:6478095 NCBI chrNW_004955493:1,937,507...1,956,248
Ensembl chrNW_004955493:1,904,220...1,956,303
JBrowse link
aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1h calcium voltage-gated channel subunit alpha1 H involved_in ISO PMID:19342457
(PMID:19342457)
UniProt PMID:19342457 RGD:4891166 NCBI chrNW_004955442:16,047,965...16,108,862
Ensembl chrNW_004955442:16,045,895...16,108,862
JBrowse link
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) BHF-UCL PMID:19584291 NCBI chrNW_004955411:450,674...557,213
Ensembl chrNW_004955411:450,674...558,650
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955414:27,466,636...27,507,186
Ensembl chrNW_004955414:27,456,770...27,508,109
JBrowse link
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO (PMID:16527843) UniProt PMID:16527843 NCBI chrNW_004955465:6,053,600...6,201,254
Ensembl chrNW_004955465:6,054,931...6,200,377
JBrowse link
G Dab2 DAB adaptor protein 2 ISO RGD PMID:17303656 RGD:7243836 NCBI chrNW_004955426:23,852,752...23,883,030 JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO (PMID:16981135) UniProt PMID:16981135 NCBI chrNW_004955452:2,319,446...2,344,740
Ensembl chrNW_004955452:2,319,446...2,344,989
JBrowse link
regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clcn2 chloride voltage-gated channel 2 involved_in ISO (PMID:29403011) UniProt PMID:29403011 NCBI chrNW_004955420:23,138,558...23,152,462
Ensembl chrNW_004955420:23,138,605...23,152,311
JBrowse link
regulation of aldosterone metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 acts_upstream_of_or_within ISO (MGI:3693138|PMID:17122062) MGI PMID:17122062 MGI:3693138 NCBI chrNW_004955437:14,749,808...15,457,274
Ensembl chrNW_004955437:14,749,914...15,454,028
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12307
    cellular process 11488
      C21-steroid hormone metabolic process 27
        aldosterone metabolic process 11
          aldosterone biosynthetic process + 8
          aldosterone catabolic process 0
          negative regulation of aldosterone metabolic process + 3
          positive regulation of aldosterone metabolic process + 3
          regulation of aldosterone metabolic process + 8
Path 2
Term Annotations click to browse term
  biological_process 12307
    biological regulation 8835
      regulation of biological quality 2564
        regulation of hormone levels 546
          hormone metabolic process 169
            mineralocorticoid metabolic process 12
              aldosterone metabolic process 11
                aldosterone biosynthetic process + 8
                aldosterone catabolic process 0
                negative regulation of aldosterone metabolic process + 3
                positive regulation of aldosterone metabolic process + 3
                regulation of aldosterone metabolic process + 8
paths to the root