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ONTOLOGY REPORT - ANNOTATIONS


Term:aldosterone metabolic process
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Accession:GO:0032341 term browser browse the term
Definition:The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
Synonyms:exact_synonym: aldosterone metabolism


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aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cacna1h calcium voltage-gated channel subunit alpha1 H JBrowse link 10 14,730,932 14,789,201 RGD:4891166
RGD:1600115
RGD:1624291
G Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 RGD:4891166
RGD:13792537
G Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 JBrowse link 7 116,248,759 116,255,205 RGD:727991
RGD:13792537
RGD:1624291
G Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 JBrowse link 7 116,155,928 116,161,781 RGD:1624291
negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp2 bone morphogenetic protein 2 JBrowse link 3 126,335,963 126,346,771 RGD:1624291
RGD:1600115
G Bmp5 bone morphogenetic protein 5 JBrowse link 8 82,669,466 82,950,273 RGD:1624291
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 JBrowse link 1 176,940,424 176,983,076 RGD:1624291
G Rest RE1-silencing transcription factor JBrowse link 14 33,131,985 33,152,019 RGD:4891166
RGD:1624291
RGD:1600115
positive regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp6 bone morphogenetic protein 6 JBrowse link 17 26,955,142 27,112,820 RGD:1624291
G Dab2 DAB adaptor protein 2 JBrowse link 2 55,747,353 55,768,848 RGD:7243836
G Wnt4 Wnt family member 4 JBrowse link 5 155,649,238 155,668,065 RGD:1600115
RGD:1624291
regulation of aldosterone biosynthetic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clcn2 chloride voltage-gated channel 2 JBrowse link 11 82,862,664 82,876,165 RGD:1600115
RGD:1624291
G LOC108348101 chloride channel protein 2 JBrowse link 11 83,883,428 83,897,396 RGD:1600115
regulation of aldosterone metabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 JBrowse link 15 344,204 1,048,849 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19678
    metabolic process 11954
      cellular metabolic process 10782
        cellular aldehyde metabolic process 65
          aldosterone metabolic process 14
            aldosterone biosynthetic process + 13
            aldosterone catabolic process 0
            negative regulation of aldosterone metabolic process + 4
            positive regulation of aldosterone metabolic process + 3
            regulation of aldosterone metabolic process + 10
Path 2
Term Annotations click to browse term
  biological_process 19678
    biological regulation 13599
      regulation of biological quality 4252
        regulation of hormone levels 585
          hormone metabolic process 214
            cellular hormone metabolic process 127
              C21-steroid hormone metabolic process 44
                aldosterone metabolic process 14
                  aldosterone biosynthetic process + 13
                  aldosterone catabolic process 0
                  negative regulation of aldosterone metabolic process + 4
                  positive regulation of aldosterone metabolic process + 3
                  regulation of aldosterone metabolic process + 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.