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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of chondrocyte differentiation
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Accession:GO:0032331 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.
Synonyms:exact_synonym: down regulation of chondrocyte differentiation;   downregulation of chondrocyte differentiation
 narrow_synonym: inhibition of chondrocyte differentiation


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negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:22247065) RGD PMID:22247065 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 involved_in ISO (PMID:22247065) RGD PMID:22247065 NCBI chr 8:90,704,727...90,744,331
Ensembl chr 8:90,704,727...90,744,328 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3714677|PMID:17481601)		 Ensembl
RGD		 PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in ISO
IEA		 (MGI:6294593|PMID:15331410)
GO_REF:0000107		 RGD
Ensembl		 PMID:15331410 GO_REF:0000107 MGI:6294593 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Chadl chondroadherin-like involved_in ISO (MGI:5617405|PMID:25451920) RGD PMID:25451920 MGI:5617405 NCBI chr 7:113,205,323...113,218,678
Ensembl chr 7:113,210,748...113,217,272 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148591|MGI:2148594|MGI:2446084|MGI:2450929 (MGI:3578464|PMID:15866163), (MGI:3701031|PMID:16818445)		 Ensembl
RGD		 PMID:15866163 PMID:16818445 GO_REF:0000107 MGI:3578464 MGI:3701031 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 involved_in ISO
ISS		 (PMID:20005202)
GO_REF:0000024		 RGD
UniProt		 PMID:20005202 GO_REF:0000024 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in ISO (PMID:21976273) RGD PMID:21976273 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:96533 (MGI:3608261|PMID:16284117) RGD PMID:16284117 MGI:3608261 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:10556075) RGD PMID:10556075 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Ihh Indian hedgehog signaling molecule acts_upstream_of_or_within ISO MGI:1934258 (MGI:3608261|PMID:16284117) RGD PMID:16284117 MGI:3608261 NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (MGI:2178869|PMID:11790802) RGD PMID:11790802 MGI:2178869 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975 		JBrowse link
G Mkx mohawk homeobox IMP RGD PMID:27370800 RGD:40924660 NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124 		JBrowse link
G Nkx3-2 NK3 homeobox 2 involved_in ISO (MGI:3617032|PMID:16421188) RGD PMID:16421188 MGI:3617032 NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061 		JBrowse link
G Pth parathyroid hormone involved_in IMP PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530 		JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (PMID:90087)
MGI:2154515|MGI:95728 (MGI:1352921|PMID:8895385), (MGI:3709778|PMID:17328886)		 RGD PMID:90087 PMID:8895385 PMID:17328886 MGI:1352921 MGI:3709778 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414736|PMID:29644115)		 UniProt
RGD		 PMID:29644115 GO_REF:0000024 MGI:6414736 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) RGD PMID:10684250 MGI:1353721 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) RGD PMID:10684250 MGI:1353721 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:19756381) RGD PMID:19756381 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within
involved_in		 ISO
ISS		 MGI:2158693 (MGI:2135696|PMID:11371614)
GO_REF:0000024		 RGD
UniProt		 PMID:11371614 GO_REF:0000024 MGI:2135696 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (MGI:3848261|PMID:19494318) RGD PMID:19494318 MGI:3848261 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350|MGI:88276 (MGI:3701031|PMID:16818445) RGD PMID:16818445 MGI:3701031 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (PMID:90087) RGD PMID:90087 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847 		JBrowse link
G Rflna refilin A acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1923816 (MGI:5570967|PMID:24436304)
PMID:21873635		 RGD PMID:24436304 PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr12:31,633,361...31,642,317
Ensembl chr12:31,633,361...31,642,317 		JBrowse link
G Rflnb refilin B acts_upstream_of_or_within
involved_in		 ISO
IBA		 MGI:1920371 (MGI:5570967|PMID:24436304)
PMID:21873635		 RGD PMID:24436304 PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19746
    cellular process 18159
      negative regulation of cellular process 5100
        negative regulation of cell differentiation 793
          negative regulation of chondrocyte differentiation 26
            negative regulation of chondrocyte development + 3
Path 2
Term Annotations click to browse term
  biological_process 19746
    developmental process 6931
      anatomical structure development 6386
        multicellular organism development 5165
          system development 4438
            skeletal system development 586
              cartilage development 231
                chondrocyte differentiation 129
                  regulation of chondrocyte differentiation 55
                    negative regulation of chondrocyte differentiation 26
                      negative regulation of chondrocyte development + 3
paths to the root