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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of chondrocyte differentiation
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Accession:GO:0032330 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of chondrocyte differentiation.


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regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN2 cellular communication network factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4413658|PMID:18597638) Ensembl
Ensembl
MGI		 PMID:18597638 GO_REF:0000107 MGI:4413658 NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,674,394...31,677,691 		JBrowse link
G GLG1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4829577|PMID:20530870) Ensembl
MGI		 PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr 6:13,011,829...13,165,487
Ensembl chr 6:13,011,837...13,164,367 		JBrowse link
G HOXA11 homeobox A11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5462316|PMID:22916278) MGI
Ensembl		 PMID:22916278 GO_REF:0000107 MGI:5462316 NCBI chr18:45,388,523...45,392,190
Ensembl chr18:45,388,375...45,391,953 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr15:81,906,654...81,910,765
Ensembl chr15:81,908,460...81,911,282 		JBrowse link
G LNPK lunapark, ER junction formation factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:5462316|PMID:22916278) Ensembl
MGI		 PMID:22916278 GO_REF:0000107 MGI:5462316 NCBI chr15:81,721,637...81,805,706
Ensembl chr15:81,721,644...81,805,680 		JBrowse link
G MAF MAF bZIP transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2676505|PMID:14512017) Ensembl
Ensembl
MGI		 PMID:14512017 GO_REF:0000107 MGI:2676505 NCBI chr 6:8,468,736...8,910,012
Ensembl chr 6:8,468,413...8,485,030 		JBrowse link
G MBOAT2 membrane bound O-acyltransferase domain containing 2 involved_in ISO (MGI:6467698|PMID:29196633) UniProt PMID:29196633 MGI:6467698 NCBI chr 3:127,243,797...127,365,443
Ensembl chr 3:127,243,275...127,360,057 		JBrowse link
G MDK midkine involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 2:16,130,787...16,133,791
Ensembl chr 2:16,130,788...16,133,510 		JBrowse link
G PTHLH parathyroid hormone like hormone involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr 5:45,750,968...45,763,421
Ensembl chr 5:45,751,292...45,763,415 		JBrowse link
G SCIN scinderin involved_in ISS UniProt
UniProt		 GO_REF:0000024 NCBI chr 9:82,103,271...82,185,254
Ensembl chr 9:82,103,087...82,185,283 		JBrowse link
G SHOX2 short stature homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3621617|PMID:16537395) Ensembl
Ensembl
MGI		 PMID:16537395 GO_REF:0000107 MGI:3621617 NCBI chr13:97,879,586...97,892,276
Ensembl chr13:97,879,281...97,889,785 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:95,460,046...95,463,428
Ensembl chr 3:95,459,945...95,463,251 		JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 involved_in ISO (MGI:3848565|PMID:19389374) UniProt PMID:19389374 MGI:3848565 NCBI chr 4:22,905,627...23,162,862
Ensembl chr 4:22,905,637...23,159,546 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:90087) MGI
Ensembl
Ensembl		 PMID:90087 GO_REF:0000107 NCBI chr 5:45,750,968...45,763,421
Ensembl chr 5:45,751,292...45,763,415 		JBrowse link
G RFLNA refilin A involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr14:28,823,571...28,841,281
Ensembl chr14:28,823,575...28,845,719 		JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:5570967|PMID:24436304)		 GO_Central
GO_Central
Ensembl
MGI		 PMID:21873635 PMID:24436304 GO_REF:0000107 MGI:5570967 NCBI chr12:47,307,657...47,316,652
Ensembl chr12:47,307,637...47,314,589 		JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr16:19,547,003...19,920,780
Ensembl chr16:19,547,011...19,920,513 		JBrowse link
G ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:47,919,398...47,994,528
Ensembl chr 7:47,929,033...47,994,453 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3714677|PMID:17481601) Ensembl
Ensembl
MGI		 PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr 1:183,415,989...183,422,888
Ensembl chr 1:183,416,146...183,422,637 		JBrowse link
G CCN4 cellular communication network factor 4 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:8,078,163...8,110,906
Ensembl chr 4:8,079,755...8,110,700 		JBrowse link
G CHADL chondroadherin like involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:7,246,892...7,258,962
Ensembl chr 5:7,248,444...7,253,170 		JBrowse link
G CTNNB1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3578464|PMID:15866163)
(MGI:3701031|PMID:16818445)		 Ensembl
MGI		 PMID:15866163 PMID:16818445 GO_REF:0000107 MGI:3578464 MGI:3701031 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:85,407,677...85,473,251
Ensembl chr 3:85,407,677...85,473,252 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr17:38,792,854...38,796,806
Ensembl chr17:38,792,187...38,797,005 		JBrowse link
G GLI2 GLI family zinc finger 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3709778|PMID:17328886) Ensembl
Ensembl
MGI		 PMID:17328886 GO_REF:0000107 MGI:3709778 NCBI chr15:30,312,528...30,580,272
Ensembl chr15:30,313,817...30,579,306 		JBrowse link
G GLI3 GLI family zinc finger 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3608261|PMID:16284117) MGI
Ensembl		 PMID:16284117 GO_REF:0000107 MGI:3608261 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,072...52,697,900 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:136,617,041...136,629,293
Ensembl chr 1:136,617,105...136,629,292 		JBrowse link
G IHH Indian hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3608261|PMID:16284117) MGI
Ensembl		 PMID:16284117 GO_REF:0000107 MGI:3608261 NCBI chr15:121,083,750...121,090,548
Ensembl chr15:121,083,753...121,090,121 		JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:2178869|PMID:11790802) Ensembl
Ensembl
MGI		 PMID:11790802 GO_REF:0000107 MGI:2178869 NCBI chr 2:6,701,455...6,720,191
Ensembl chr 2:6,701,510...6,720,153 		JBrowse link
G MKX mohawk homeobox ISO RGD PMID:27370800 RGD:40924660 NCBI chr10:39,096,778...39,173,384
Ensembl chr10:39,096,782...39,172,198 		JBrowse link
G NKX3-2 NK3 homeobox 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 8:9,179,061...9,183,340
Ensembl chr 8:9,179,232...9,182,892 		JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 2:45,757,398...45,760,433
Ensembl chr 2:45,757,398...45,760,415 		JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709778|PMID:17328886)
(PMID:90087)
(MGI:1352921|PMID:8895385)		 MGI
Ensembl		 PMID:90087 PMID:8895385 PMID:17328886 GO_REF:0000107 MGI:1352921 MGI:3709778 NCBI chr 5:45,750,968...45,763,421
Ensembl chr 5:45,751,292...45,763,415 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,169...39,292,003 		JBrowse link
G RARB retinoic acid receptor beta acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) MGI PMID:10684250 MGI:1353721 NCBI chr13:12,336,387...12,507,688
Ensembl chr13:12,336,972...12,507,680 		JBrowse link
G RARG retinoic acid receptor gamma involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1353721|PMID:10684250) Ensembl
Ensembl
MGI		 PMID:10684250 GO_REF:0000107 MGI:1353721 NCBI chr 5:18,436,267...18,458,625
Ensembl chr 5:18,436,270...18,458,624 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 IEA
ISS
ISO		 (MGI:2135696|PMID:11371614) Ensembl
Ensembl
UniProt
MGI
UniProt		 PMID:11371614 GO_REF:0000024 GO_REF:0000107 MGI:2135696 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:240,842,735...240,918,267
Ensembl chr 1:240,860,156...240,918,528 		JBrowse link
G WNT9A Wnt family member 9A acts_upstream_of_or_within ISO (MGI:3701031|PMID:16818445) MGI PMID:16818445 MGI:3701031 NCBI chr 2:51,102,757...51,128,346
Ensembl chr 2:51,102,763...51,128,346 		JBrowse link
positive regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA11 homeobox A11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3043491|PMID:14668414) MGI
Ensembl		 PMID:14668414 GO_REF:0000107 MGI:3043491 NCBI chr18:45,388,523...45,392,190
Ensembl chr18:45,388,375...45,391,953 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr15:81,906,654...81,910,765
Ensembl chr15:81,908,460...81,911,282 		JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:23077084 RGD:7242190 NCBI chr 7:5,058,817...5,208,868
Ensembl chr 7:5,058,817...5,210,270 		JBrowse link
G FGF18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3584218|PMID:15781473) Ensembl
Ensembl
MGI		 PMID:15781473 GO_REF:0000107 MGI:3584218 NCBI chr16:52,724,867...52,760,246
Ensembl chr16:52,725,356...52,759,791 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3819026|PMID:18363966)
(MGI:1329266|PMID:9885252)		 Ensembl
Ensembl
MGI		 PMID:9885252 PMID:18363966 GO_REF:0000107 MGI:1329266 MGI:3819026 NCBI chr17:38,792,854...38,796,806
Ensembl chr17:38,792,187...38,797,005 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 4:40,473,015...40,491,142
Ensembl chr 4:40,472,935...40,490,033 		JBrowse link
G GLI3 GLI family zinc finger 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3709778|PMID:17328886) Ensembl
Ensembl
MGI		 PMID:17328886 GO_REF:0000107 MGI:3709778 NCBI chr18:52,403,463...52,697,906
Ensembl chr18:52,404,072...52,697,900 		JBrowse link
G HOXA11 homeobox A11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3043491|PMID:14668414) Ensembl
Ensembl
MGI		 PMID:14668414 GO_REF:0000107 MGI:3043491 NCBI chr18:45,388,523...45,392,190
Ensembl chr18:45,388,375...45,391,953 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr15:81,906,654...81,910,765
Ensembl chr15:81,908,460...81,911,282 		JBrowse link
G LOXL2 lysyl oxidase like 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr14:7,435,861...7,540,699
Ensembl chr14:7,435,867...7,540,704 		JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:98,258,456...98,268,539
Ensembl chr 3:98,258,463...98,268,553 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 3:10,212,734...10,272,184
Ensembl chr 3:10,212,735...10,281,823 		JBrowse link
G PRKG2 protein kinase cGMP-dependent 2 ISO RGD PMID:15466490 RGD:150429792 NCBI chr 8:136,754,698...136,854,589
Ensembl chr 8:136,755,469...136,852,906 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO RGD PMID:17884819 RGD:2298851 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G RUNX2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1332911|PMID:10072783) Ensembl
MGI		 PMID:10072783 GO_REF:0000107 MGI:1332911 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:164,998,457...165,124,455
Ensembl chr 1:164,998,103...165,124,449 		JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in IBA
IEA		 (PMID:21873635) GO_Central
GO_Central
Ensembl
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr 5:49,159,950...50,166,463
Ensembl chr 5:49,504,551...50,161,558 		JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl
GO_Central		 PMID:21873635 GO_REF:0000107 NCBI chr 2:42,447,391...43,068,824
Ensembl chr 2:42,453,681...43,068,325 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in IEA
ISS
IBA		 (PMID:21873635) Ensembl
Ensembl
UniProt
GO_Central
GO_Central
UniProt		 PMID:21873635 GO_REF:0000024 GO_REF:0000107 NCBI chr12:8,642,154...8,647,315
Ensembl chr12:8,642,158...8,647,315 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:15647824 RGD:1601663 NCBI chr13:10,900,716...11,360,587
Ensembl chr13:10,900,724...11,359,544 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 9:41,639,536...41,839,254
Ensembl chr 9:41,639,701...41,836,742 		JBrowse link
G ZNF219 zinc finger protein 219 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 7:78,028,560...78,043,491
Ensembl chr 7:78,035,228...78,043,464 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD7 SMAD family member 7 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 1:98,512,800...98,543,924
Ensembl chr 1:98,514,267...98,542,382 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4818263|PMID:19623616) Ensembl
Ensembl
MGI		 PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr12:12,311,293...12,343,207
Ensembl chr12:12,311,298...12,343,200 		JBrowse link
G RFLNA refilin A involved_in IEA InterPro
InterPro		 GO_REF:0000002 NCBI chr14:28,823,571...28,841,281
Ensembl chr14:28,823,575...28,845,719 		JBrowse link
G RFLNB refilin B involved_in IEA InterPro GO_REF:0000002 NCBI chr12:47,307,657...47,316,652
Ensembl chr12:47,307,637...47,314,589 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17636
    developmental process 6654
      regulation of developmental process 2661
        regulation of cell differentiation 1707
          regulation of chondrocyte differentiation 55
            negative regulation of chondrocyte differentiation + 26
            positive regulation of chondrocyte differentiation + 21
            regulation of chondrocyte development + 7
            regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 17636
    developmental process 6654
      anatomical structure development 6182
        multicellular organism development 5002
          system development 4335
            skeletal system development 580
              cartilage development 228
                chondrocyte differentiation 129
                  regulation of chondrocyte differentiation 55
                    negative regulation of chondrocyte differentiation + 26
                    positive regulation of chondrocyte differentiation + 21
                    regulation of chondrocyte development + 7
                    regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
paths to the root