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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of chondrocyte differentiation
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Accession:GO:0032330 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of chondrocyte differentiation.


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regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 acts_upstream_of_or_within IMP (MGI:4413658|PMID:18597638) MGI PMID:18597638 MGI:4413658 NCBI chr10:24,471,340...24,474,581
Ensembl chr10:24,471,340...24,474,581 		JBrowse link
G Glg1 golgi apparatus protein 1 acts_upstream_of_or_within IMP (MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:4829577 NCBI chr 8:111,879,916...111,985,842
Ensembl chr 8:111,881,053...111,985,848 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within IGI (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr 6:52,219,085...52,222,790
Ensembl chr 6:52,219,086...52,222,790 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within IGI (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr 2:74,509,902...74,517,360
Ensembl chr 2:74,509,901...74,517,360 		JBrowse link
G Lnpk lunapark, ER junction formation factor acts_upstream_of_or_within IMP (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr 2:74,345,180...74,409,802
Ensembl chr 2:74,350,635...74,409,779 		JBrowse link
G Maf MAF bZIP transcription factor acts_upstream_of_or_within IMP (MGI:2676505|PMID:14512017) MGI PMID:14512017 MGI:2676505 NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in IMP (MGI:6467698|PMID:29196633) UniProt PMID:29196633 MGI:6467698 NCBI chr12:24,881,401...25,014,399
Ensembl chr12:24,880,878...25,014,396 		JBrowse link
G Mdk midkine involved_in IMP (MGI:5693192|PMID:25551381) UniProt PMID:25551381 MGI:5693192 NCBI chr 2:91,760,150...91,762,642
Ensembl chr 2:91,760,150...91,762,642 		JBrowse link
G Pthlh parathyroid hormone-like peptide involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Shox2 short stature homeobox 2 acts_upstream_of_or_within IMP (MGI:3621617|PMID:16537395) MGI PMID:16537395 MGI:3621617 NCBI chr 3:66,879,056...66,889,104
Ensembl chr 3:66,879,060...66,889,104 		JBrowse link
G Six2 sine oculis-related homeobox 2 involved_in IMP (MGI:4822095|PMID:20515681) UniProt PMID:20515681 MGI:4822095 NCBI chr17:85,970,276...85,995,682
Ensembl chr17:85,991,705...85,995,702 		JBrowse link
G Trps1 transcriptional repressor GATA binding 1 involved_in IMP (MGI:3848565|PMID:19389374) UniProt PMID:19389374 MGI:3848565 NCBI chr15:50,518,149...50,754,027
Ensembl chr15:50,518,148...50,753,859 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like peptide acts_upstream_of_or_within ISO (MGI:85084|PMID:9008714) MGI PMID:9008714 MGI:85084 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Rflna refilin A acts_upstream_of_or_within
involved_in		 IGI
IBA		 (MGI:5570967|PMID:24436304)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:21873635 PMID:24436304 MGI:5570967 MGI:6201960 NCBI chr 5:125,080,512...125,089,611
Ensembl chr 5:125,080,285...125,089,611 		JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within		 IBA
IGI		 (MGI:6201960|PMID:21873635)
(MGI:5570967|PMID:24436304)		 GO_Central
MGI		 PMID:21873635 PMID:24436304 MGI:5570967 MGI:6201960 NCBI chr11:75,910,020...75,918,608
Ensembl chr11:75,910,020...75,918,608 		JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr15:11,064,781...11,349,321
Ensembl chr15:11,064,876...11,349,317 		JBrowse link
G Adamts7 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 7 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:90,041,420...90,082,155
Ensembl chr 9:90,045,122...90,090,124 		JBrowse link
G Bmp4 bone morphogenetic protein 4 acts_upstream_of_or_within IDA (MGI:3714677|PMID:17481601) MGI PMID:17481601 MGI:3714677 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in IMP (MGI:6294593|PMID:15331410) UniProt PMID:15331410 MGI:6294593 NCBI chr15:66,763,218...66,795,054
Ensembl chr15:66,763,169...66,795,050 		JBrowse link
G Chadl chondroadherin-like involved_in IMP (MGI:5617405|PMID:25451920) UniProt PMID:25451920 MGI:5617405 NCBI chr15:81,570,366...81,581,564
Ensembl chr15:81,562,497...81,581,488 		JBrowse link
G Ctnnb1 catenin (cadherin associated protein), beta 1 acts_upstream_of_or_within IGI
IMP		 (MGI:3701031|PMID:16818445)
(MGI:3578464|PMID:15866163)		 MGI PMID:15866163 PMID:16818445 MGI:3578464 MGI:3701031 NCBI chr 9:120,762,466...120,789,573
Ensembl chr 9:120,758,282...120,789,573 		JBrowse link
G Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr11:28,803,154...28,876,743
Ensembl chr11:28,803,204...28,876,743 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:155,782,943...155,787,287
Ensembl chr 2:155,782,943...155,787,287 		JBrowse link
G Gli2 GLI-Kruppel family member GLI2 acts_upstream_of_or_within IMP (MGI:3709778|PMID:17328886) MGI PMID:17328886 MGI:3709778 NCBI chr 1:118,761,791...118,987,578
Ensembl chr 1:118,761,862...118,981,349 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 acts_upstream_of_or_within IGI (MGI:3608261|PMID:16284117) MGI PMID:16284117 MGI:3608261 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:113,579,020...113,588,993
Ensembl chr 2:113,576,509...113,588,991 		JBrowse link
G Ihh Indian hedgehog acts_upstream_of_or_within IMP (MGI:3608261|PMID:16284117) MGI PMID:16284117 MGI:3608261 NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within IMP (MGI:2178869|PMID:11790802) MGI PMID:11790802 MGI:2178869 NCBI chr19:5,790,928...5,808,564
Ensembl chr19:5,790,932...5,808,560 		JBrowse link
G Mkx mohawk homeobox involved_in ISO RGD
MGI		 PMID:27370800 GO_REF:0000096 MGI:4417868 RGD:40924660 NCBI chr18:6,934,966...7,004,779
Ensembl chr18:6,934,518...7,004,780 		JBrowse link
G Nkx3-2 NK3 homeobox 2 involved_in IMP (MGI:3617032|PMID:16421188) UniProt PMID:16421188 MGI:3617032 NCBI chr 5:41,918,826...41,921,563
Ensembl chr 5:41,918,826...41,921,844 		JBrowse link
G Pth parathyroid hormone involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 7:112,984,783...112,987,879
Ensembl chr 7:112,984,787...112,987,777 		JBrowse link
G Pthlh parathyroid hormone-like peptide acts_upstream_of_or_within IGI
IMP
ISO
IDA		 (MGI:3709778|PMID:17328886)
(MGI:1352921|PMID:8895385)
(MGI:85084|PMID:9008714)		 MGI PMID:8895385 PMID:9008714 PMID:17328886 MGI:1352921 MGI:3709778 MGI:85084 NCBI chr 6:147,153,607...147,165,511
Ensembl chr 6:147,153,599...147,165,681 		JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in IMP (MGI:6414736|PMID:29644115) UniProt PMID:29644115 MGI:6414736 NCBI chr 5:121,268,596...121,329,460
Ensembl chr 5:121,268,596...121,329,460 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within IMP (MGI:1353721|PMID:10684250) MGI PMID:10684250 MGI:1353721 NCBI chr14:5,387,365...6,038,924
Ensembl chr14:5,650,540...6,038,924 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within IMP (MGI:1353721|PMID:10684250) MGI PMID:10684250 MGI:1353721 NCBI chr15:102,143,373...102,165,957
Ensembl chr15:102,143,373...102,165,952 		JBrowse link
G Snai2 snail family zinc finger 2 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 acts_upstream_of_or_within IMP (MGI:2135696|PMID:11371614) MGI PMID:11371614 MGI:2135696 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I involved_in IMP (MGI:3848261|PMID:19494318) BHF-UCL PMID:19494318 MGI:3848261 NCBI chr 4:47,353,222...47,414,926
Ensembl chr 4:47,353,222...47,414,931 		JBrowse link
G Wnt9a wingless-type MMTV integration site family, member 9A acts_upstream_of_or_within IMP
IGI		 (MGI:3701031|PMID:16818445) MGI PMID:16818445 MGI:3701031 NCBI chr11:59,197,675...59,224,378
Ensembl chr11:59,197,754...59,224,378 		JBrowse link
positive regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hoxa11 homeobox A11 acts_upstream_of_or_within IGI (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr 6:52,219,085...52,222,790
Ensembl chr 6:52,219,086...52,222,790 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within IGI (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr 2:74,509,902...74,517,360
Ensembl chr 2:74,509,901...74,517,360 		JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 involved_in ISO RGD
MGI		 PMID:23077084 GO_REF:0000096 MGI:4417868 RGD:7242190 NCBI chr13:38,529,692...38,684,290
Ensembl chr13:38,529,083...38,684,278 		JBrowse link
G Fgf18 fibroblast growth factor 18 acts_upstream_of_or_within IGI (MGI:3584218|PMID:15781473) MGI PMID:15781473 MGI:3584218 NCBI chr11:33,066,970...33,097,400
Ensembl chr11:33,067,430...33,097,400 		JBrowse link
G Gdf5 growth differentiation factor 5 acts_upstream_of_or_within
involved_in		 IDA
IGI
ISO		 (MGI:1329266|PMID:9885252)
(MGI:3819026|PMID:18363966)		 MGI PMID:9885252 PMID:18363966 GO_REF:0000096 MGI:1329266 MGI:3819026 MGI:4834177 NCBI chr 2:155,782,943...155,787,287
Ensembl chr 2:155,782,943...155,787,287 		JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 4:9,844,372...9,862,345
Ensembl chr 4:9,844,372...9,862,345 		JBrowse link
G Gli3 GLI-Kruppel family member GLI3 acts_upstream_of_or_within IMP (MGI:3709778|PMID:17328886) MGI PMID:17328886 MGI:3709778 NCBI chr13:15,638,308...15,904,611
Ensembl chr13:15,637,820...15,904,611 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within IGI (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr 6:52,219,085...52,222,790
Ensembl chr 6:52,219,086...52,222,790 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within IGI (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr 2:74,509,902...74,517,360
Ensembl chr 2:74,509,901...74,517,360 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IMP (MGI:5320274|PMID:21071451) UniProt PMID:21071451 MGI:5320274 NCBI chr14:69,846,085...69,933,283
Ensembl chr14:69,846,517...69,933,283 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within IMP
IDA		 (MGI:5703727|PMID:19410023) MGI PMID:19410023 MGI:5703727 NCBI chr14:30,601,214...30,603,567
Ensembl chr14:30,601,157...30,603,567 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in IMP (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) UniProt PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr17:83,522,712...83,532,498
Ensembl chr17:83,522,721...83,532,499 		JBrowse link
G Por cytochrome p450 oxidoreductase involved_in ISO RGD
MGI		 PMID:19264869 GO_REF:0000096 MGI:4417868 RGD:2316785 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180 		JBrowse link
G Prkg2 protein kinase, cGMP-dependent, type II involved_in ISO RGD
MGI		 PMID:15466490 GO_REF:0000096 MGI:4417868 RGD:150429792 NCBI chr 5:99,077,632...99,185,042
Ensembl chr 5:99,077,632...99,185,210 		JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) involved_in ISO RGD
MGI		 PMID:17884819 GO_REF:0000096 MGI:4417868 RGD:2298851 NCBI chr19:5,687,569...5,698,162
Ensembl chr19:5,687,511...5,698,158 		JBrowse link
G Runx2 runt related transcription factor 2 acts_upstream_of_or_within IMP (MGI:1332911|PMID:10072783) MGI PMID:10072783 MGI:1332911 NCBI chr17:44,806,874...45,125,684
Ensembl chr17:44,806,874...45,125,684 		JBrowse link
G Smad3 SMAD family member 3 involved_in IMP (MGI:5285145|PMID:21035443) UniProt PMID:21035443 MGI:5285145 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276 		JBrowse link
G Sox5 SRY (sex determining region Y)-box 5 involved_in ISO
IDA
IBA		 (MGI:5285147|PMID:20940257)
(MGI:6201960|PMID:21873635)		 MGI
UniProt
GO_Central		 PMID:20940257 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5285147 MGI:6201960 NCBI chr 6:143,774,151...144,728,008
Ensembl chr 6:143,774,151...144,727,703 		JBrowse link
G Sox6 SRY (sex determining region Y)-box 6 involved_in IBA
ISO
IDA		 (MGI:6201960|PMID:21873635)
(MGI:5285147|PMID:20940257)		 GO_Central
MGI
UniProt		 PMID:20940257 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:5285147 MGI:6201960 NCBI chr 7:115,070,107...115,639,186
Ensembl chr 7:115,070,107...115,638,031 		JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 involved_in IMP
ISO
IDA
IBA		 (MGI:4950303|PMID:21367821)
(MGI:5285147|PMID:20940257)
(MGI:6201960|PMID:21873635)		 UniProt
MGI
GO_Central		 PMID:20940257 PMID:21367821 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:4950303 MGI:5285147 MGI:6201960 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586 		JBrowse link
G Thrb thyroid hormone receptor beta involved_in ISO RGD
MGI		 PMID:15647824 GO_REF:0000096 MGI:4417868 RGD:1601663 NCBI chr14:4,429,599...4,810,538
Ensembl chr14:4,431,611...4,809,435 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 9:48,563,097...48,747,525
Ensembl chr 9:48,565,597...48,747,522 		JBrowse link
G Zfp219 zinc finger protein 219 involved_in IMP (MGI:5285147|PMID:20940257) UniProt PMID:20940257 MGI:5285147 NCBI chr14:52,243,532...52,258,597
Ensembl chr14:52,243,534...52,258,190 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IDA (MGI:6377914|PMID:29503843) CACAO PMID:29503843 MGI:6377914 NCBI chr18:75,500,436...75,529,006
Ensembl chr18:75,500,600...75,529,006 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 acts_upstream_of_or_within IMP (MGI:4818263|PMID:19623616) MGI PMID:19623616 MGI:4818263 NCBI chr11:108,808,654...108,841,609
Ensembl chr11:108,811,175...108,841,609 		JBrowse link
G Rflna refilin A involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 5:125,080,512...125,089,611
Ensembl chr 5:125,080,285...125,089,611 		JBrowse link
G Rflnb refilin B involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr11:75,910,020...75,918,608
Ensembl chr11:75,910,020...75,918,608 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28449
    developmental process 7304
      regulation of developmental process 2870
        regulation of cell differentiation 1849
          regulation of chondrocyte differentiation 55
            negative regulation of chondrocyte differentiation + 26
            positive regulation of chondrocyte differentiation + 22
            regulation of chondrocyte development + 7
            regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 28449
    developmental process 7304
      anatomical structure development 6712
        multicellular organism development 5345
          system development 4571
            skeletal system development 602
              cartilage development 236
                chondrocyte differentiation 128
                  regulation of chondrocyte differentiation 55
                    negative regulation of chondrocyte differentiation + 26
                    positive regulation of chondrocyte differentiation + 22
                    regulation of chondrocyte development + 7
                    regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
paths to the root