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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of chondrocyte differentiation
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Accession:GO:0032330 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of chondrocyte differentiation.


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regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN2 cellular communication network factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4413658|PMID:18597638) Ensembl
MGI		 PMID:18597638 GO_REF:0000107 MGI:4413658 NCBI chr 1:25,508,082...25,511,058
Ensembl chr 1:25,507,662...25,510,145 		JBrowse link
G GLG1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:4829577|PMID:20530870) Ensembl
Ensembl
MGI		 PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr 5:76,020,743...76,171,477
Ensembl chr 5:76,020,084...76,167,007 		JBrowse link
G HOXA11 homeobox A11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5462316|PMID:22916278) MGI
Ensembl		 PMID:22916278 GO_REF:0000107 MGI:5462316 NCBI chr14:40,355,907...40,360,120
Ensembl chr14:40,357,478...40,359,919 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr36:19,913,064...19,926,868
Ensembl chr36:19,914,431...19,916,766 		JBrowse link
G LNPK lunapark, ER junction formation factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5462316|PMID:22916278) MGI
Ensembl
Ensembl		 PMID:22916278 GO_REF:0000107 MGI:5462316 NCBI chr36:19,731,523...19,809,349
Ensembl chr36:19,732,276...19,808,769 		JBrowse link
G LOC491316 midkine involved_in ISO (MGI:5693192|PMID:25551381) UniProt PMID:25551381 MGI:5693192 NCBI chr 9:55,100,491...55,101,081 JBrowse link
G MAF MAF bZIP transcription factor acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2676505|PMID:14512017) MGI
Ensembl		 PMID:14512017 GO_REF:0000107 MGI:2676505 NCBI chr 5:71,965,291...71,982,903
Ensembl chr 5:71,965,500...71,981,735 		JBrowse link
G MBOAT2 membrane bound O-acyltransferase domain containing 2 involved_in ISO (MGI:6467698|PMID:29196633) UniProt PMID:29196633 MGI:6467698 NCBI chr17:6,090,746...6,217,139
Ensembl chr17:6,094,900...6,213,142 		JBrowse link
G PTHLH parathyroid hormone like hormone involved_in IBA (PMID:21873635) GO_Central
GO_Central		 PMID:21873635 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078 		JBrowse link
G SHOX2 short stature homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3621617|PMID:16537395) Ensembl
Ensembl
MGI		 PMID:16537395 GO_REF:0000107 MGI:3621617 NCBI chr23:51,484,696...51,492,586
Ensembl chr23:51,484,421...51,492,566 		JBrowse link
G SIX2 SIX homeobox 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr10:47,399,152...47,403,503
Ensembl chr10:47,400,034...47,403,509 		JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 involved_in ISO (MGI:3848565|PMID:19389374) UniProt PMID:19389374 MGI:3848565 NCBI chr13:15,017,180...15,273,177
Ensembl chr13:15,022,652...15,273,666 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:90087) MGI
Ensembl
Ensembl		 PMID:90087 GO_REF:0000107 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078 		JBrowse link
G RFLNA refilin A involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:5,501,223...5,509,118
Ensembl chr26:5,502,106...5,505,458 		JBrowse link
G RFLNB refilin B involved_in
acts_upstream_of_or_within		 IBA
IEA
ISO		 (PMID:21873635)
(MGI:5570967|PMID:24436304)		 GO_Central
Ensembl
MGI		 PMID:21873635 PMID:24436304 GO_REF:0000107 MGI:5570967 NCBI chr 9:45,232,910...45,239,569
Ensembl chr 9:45,232,975...45,239,130 		JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:73,887,959...74,188,909
Ensembl chr 4:73,887,924...74,001,984 		JBrowse link
G ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif 7 involved_in ISO (PMID:22247065) BHF-UCL PMID:22247065 NCBI chr 3:58,182,316...58,223,194
Ensembl chr 3:58,188,004...58,226,185 		JBrowse link
G BMP4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3714677|PMID:17481601) Ensembl
Ensembl
MGI		 PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr 8:29,997,563...30,254,307
Ensembl chr 8:29,997,569...30,004,557 		JBrowse link
G CCN4 cellular communication network factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:29,648,720...29,683,822
Ensembl chr13:29,648,639...29,679,732 		JBrowse link
G CHADL chondroadherin like involved_in ISO (MGI:5617405|PMID:25451920) UniProt PMID:25451920 MGI:5617405 NCBI chr10:23,992,848...24,006,492
Ensembl chr10:23,953,912...24,003,162 		JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3701031|PMID:16818445)
(MGI:3578464|PMID:15866163)		 MGI
Ensembl		 PMID:15866163 PMID:16818445 GO_REF:0000107 MGI:3578464 MGI:3701031 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927 		JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:56,632,801...56,694,872
Ensembl chr10:56,579,899...56,787,187 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GLI2 GLI family zinc finger 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709778|PMID:17328886) MGI
Ensembl		 PMID:17328886 GO_REF:0000107 MGI:3709778 NCBI chr19:29,128,401...29,383,324
Ensembl chr19:29,130,227...29,383,658 		JBrowse link
G GLI3 GLI family zinc finger 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3608261|PMID:16284117) MGI
Ensembl		 PMID:16284117 GO_REF:0000107 MGI:3608261 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr30:2,219,535...2,231,868
Ensembl chr30:2,222,898...2,225,418 		JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in IEA Ensembl GO_REF:0000107
G IHH Indian hedgehog signaling molecule acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3608261|PMID:16284117) MGI
Ensembl		 PMID:16284117 GO_REF:0000107 MGI:3608261 NCBI chr37:25,616,942...25,622,989 JBrowse link
G LOC487079 homeobox protein Mohawk ISO RGD PMID:27370800 RGD:40924660 NCBI chr 2:5,898,155...5,964,577 JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2178869|PMID:11790802) MGI
Ensembl		 PMID:11790802 GO_REF:0000107 MGI:2178869 NCBI chr18:51,653,783...51,667,793
Ensembl chr18:51,659,098...51,667,433 		JBrowse link
G NKX3-2 NK3 homeobox 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 3:66,543,046...66,546,779
Ensembl chr 3:66,543,046...66,545,580 		JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr21:36,417,062...36,419,967
Ensembl chr21:36,417,058...36,419,967 		JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1352921|PMID:8895385)
(PMID:90087)
(MGI:3709778|PMID:17328886)		 MGI
Ensembl		 PMID:90087 PMID:8895385 PMID:17328886 GO_REF:0000107 MGI:1352921 MGI:3709778 NCBI chr27:19,781,557...19,795,078
Ensembl chr27:19,781,557...19,795,078 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,989,218...10,072,245
Ensembl chr26:9,989,425...10,067,481 		JBrowse link
G RARB retinoic acid receptor beta involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:1353721|PMID:10684250) Ensembl
Ensembl
MGI		 PMID:10684250 GO_REF:0000107 MGI:1353721 NCBI chr23:18,207,253...18,931,128
Ensembl chr23:18,207,760...18,482,652 		JBrowse link
G RARG retinoic acid receptor gamma acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1353721|PMID:10684250) MGI
Ensembl
Ensembl		 PMID:10684250 GO_REF:0000107 MGI:1353721 NCBI chr27:1,958,432...1,978,471
Ensembl chr27:1,958,204...1,978,476 		JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr29:1,154,132...1,156,653
Ensembl chr29:1,154,036...1,156,653 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 (MGI:2135696|PMID:11371614) UniProt
UniProt
MGI		 PMID:11371614 GO_REF:0000024 MGI:2135696 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:56,191,383...56,223,042
Ensembl chr11:56,161,772...56,218,594 		JBrowse link
G WNT9A Wnt family member 9A acts_upstream_of_or_within ISO (MGI:3701031|PMID:16818445) MGI PMID:16818445 MGI:3701031 NCBI chr14:946,843...959,289
Ensembl chr14:953,244...959,295 		JBrowse link
positive regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOXA11 homeobox A11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3043491|PMID:14668414) MGI
Ensembl		 PMID:14668414 GO_REF:0000107 MGI:3043491 NCBI chr14:40,355,907...40,360,120
Ensembl chr14:40,357,478...40,359,919 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr36:19,913,064...19,926,868
Ensembl chr36:19,914,431...19,916,766 		JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:23077084 RGD:7242190 NCBI chr35:7,780,763...7,833,095
Ensembl chr35:7,804,231...7,831,845 		JBrowse link
G FGF18 fibroblast growth factor 18 acts_upstream_of_or_within ISO (MGI:3584218|PMID:15781473) MGI PMID:15781473 MGI:3584218 NCBI chr 4:40,714,891...40,748,892
Ensembl chr 4:40,715,060...40,748,518 		JBrowse link
G GDF5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (MGI:3819026|PMID:18363966)
(MGI:1329266|PMID:9885252)		 Ensembl
Ensembl
MGI		 PMID:9885252 PMID:18363966 GO_REF:0000107 MGI:1329266 MGI:3819026 NCBI chr24:24,395,699...24,400,302
Ensembl chr24:24,395,263...24,399,928 		JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (PMID:26643732) UniProt PMID:26643732 NCBI chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174
Ensembl chr29:40,676,851...40,694,174 		JBrowse link
G GLI3 GLI family zinc finger 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709778|PMID:17328886) MGI
Ensembl		 PMID:17328886 GO_REF:0000107 MGI:3709778 NCBI chr18:7,800,817...8,071,531
Ensembl chr18:7,801,394...8,068,132 		JBrowse link
G HOXA11 homeobox A11 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3043491|PMID:14668414) MGI
Ensembl		 PMID:14668414 GO_REF:0000107 MGI:3043491 NCBI chr14:40,355,907...40,360,120
Ensembl chr14:40,357,478...40,359,919 		JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr36:19,913,064...19,926,868
Ensembl chr36:19,914,431...19,916,766 		JBrowse link
G LOXL2 lysyl oxidase like 2 involved_in ISO (MGI:5320274|PMID:21071451) UniProt PMID:21071451 MGI:5320274 NCBI chr25:34,095,858...34,186,775
Ensembl chr25:34,126,335...34,185,969 		JBrowse link
G MUSTN1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5703727|PMID:19410023) MGI
Ensembl		 PMID:19410023 GO_REF:0000107 MGI:5703727
G PKDCC protein kinase domain containing, cytoplasmic involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:33,659,352...33,669,237
Ensembl chr17:33,659,272...33,668,892 		JBrowse link
G POR cytochrome p450 oxidoreductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 6:7,247,780...7,316,282
Ensembl chr 6:7,263,574...7,316,297 		JBrowse link
G PRKG2 protein kinase cGMP-dependent 2 ISO RGD PMID:15466490 RGD:150429792 NCBI chr32:5,266,435...5,365,396
Ensembl chr32:5,266,442...5,365,396 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO RGD PMID:17884819 RGD:2298851 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875 		JBrowse link
G RUNX2 RUNX family transcription factor 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:1332911|PMID:10072783) MGI
Ensembl		 PMID:10072783 GO_REF:0000107 MGI:1332911 NCBI chr12:13,723,535...13,842,565
Ensembl chr12:13,628,539...13,840,785
Ensembl chr12:13,628,539...13,840,785 		JBrowse link
G SMAD3 SMAD family member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:31,246,313...31,360,098
Ensembl chr30:31,245,657...31,363,337 		JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr27:22,857,661...23,855,709
Ensembl chr27:23,452,985...23,851,380 		JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in IBA
IEA		 (PMID:21873635) GO_Central
Ensembl		 PMID:21873635 GO_REF:0000107 NCBI chr21:38,737,072...39,320,257
Ensembl chr21:38,737,247...39,216,549 		JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in IBA
ISS		 (PMID:21873635) GO_Central
GO_Central
UniProt
UniProt		 PMID:21873635 GO_REF:0000024 NCBI chr 9:8,275,049...8,278,172
Ensembl chr 9:8,275,049...8,278,172 		JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:15647824 RGD:1601663 NCBI chr23:19,278,650...19,648,547
Ensembl chr23:19,277,493...19,660,283 		JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in IEA Ensembl
Ensembl		 GO_REF:0000107 NCBI chr 5:19,082,594...19,284,360
Ensembl chr 5:19,087,154...19,267,628 		JBrowse link
G ZNF219 zinc finger protein 219 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,178,861...18,186,650
Ensembl chr15:18,180,901...18,192,773 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD7 SMAD family member 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:79,706,485...79,734,673
Ensembl chr 7:79,706,705...79,734,749 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN2 axin 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:4818263|PMID:19623616) MGI
Ensembl		 PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr 9:14,559,476...14,588,950
Ensembl chr 9:14,559,388...14,588,530 		JBrowse link
G RFLNA refilin A involved_in IEA InterPro GO_REF:0000002 NCBI chr26:5,501,223...5,509,118
Ensembl chr26:5,502,106...5,505,458 		JBrowse link
G RFLNB refilin B involved_in IEA InterPro GO_REF:0000002 NCBI chr 9:45,232,910...45,239,569
Ensembl chr 9:45,232,975...45,239,130 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17405
    developmental process 6675
      regulation of developmental process 2706
        regulation of cell differentiation 1737
          regulation of chondrocyte differentiation 56
            negative regulation of chondrocyte differentiation + 27
            positive regulation of chondrocyte differentiation + 22
            regulation of chondrocyte development + 7
            regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 17405
    developmental process 6675
      anatomical structure development 6206
        multicellular organism development 5064
          system development 4374
            skeletal system development 591
              cartilage development 233
                chondrocyte differentiation 133
                  regulation of chondrocyte differentiation 56
                    negative regulation of chondrocyte differentiation + 27
                    positive regulation of chondrocyte differentiation + 22
                    regulation of chondrocyte development + 7
                    regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
paths to the root