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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of chondrocyte differentiation
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Accession:GO:0032330 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of chondrocyte differentiation.



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regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CCN2 cellular communication network factor 2 acts_upstream_of_or_within ISO (MGI:4413658|PMID:18597638) MGI PMID:18597638 MGI:4413658 NCBI chr 6:129,729,572...129,733,113
Ensembl chr 6:133,836,319...133,842,077
JBrowse link
G GLG1 golgi glycoprotein 1 acts_upstream_of_or_within ISO (MGI:4829577|PMID:20530870) MGI PMID:20530870 MGI:4829577 NCBI chr16:55,014,892...55,172,877
Ensembl chr16:74,372,660...74,526,764
JBrowse link
G HOXA11 homeobox A11 acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr 7:27,826,003...27,829,757
Ensembl chr 7:27,424,759...27,429,103
JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr2B:63,386,806...63,398,777 JBrowse link
G LNPK lunapark, ER junction formation factor acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) MGI PMID:22916278 MGI:5462316 NCBI chr2B:63,197,335...63,279,473
Ensembl chr2B:180,909,968...180,989,448
JBrowse link
G MAF MAF bZIP transcription factor acts_upstream_of_or_within ISO (MGI:2676505|PMID:14512017) MGI PMID:14512017 MGI:2676505 NCBI chr16:60,188,494...60,194,871 JBrowse link
G MBOAT2 membrane bound O-acyltransferase domain containing 2 involved_in ISO (MGI:6467698|PMID:29196633) UniProt PMID:29196633 MGI:6467698 NCBI chr2A:8,852,201...9,003,084
Ensembl chr2A:9,024,381...9,127,069
JBrowse link
G MDK midkine involved_in ISO (MGI:5693192|PMID:25551381) UniProt PMID:25551381 MGI:5693192 NCBI chr11:46,339,365...46,342,388
Ensembl chr11:46,891,540...46,893,254
JBrowse link
G PRKG2 protein kinase cGMP-dependent 2 ISO RGD PMID:15466490 RGD:150429792 NCBI chr 4:42,987,217...43,114,993
Ensembl chr 4:48,836,953...48,960,383
JBrowse link
G SHOX2 short stature homeobox 2 acts_upstream_of_or_within ISO (MGI:3621617|PMID:16537395) MGI PMID:16537395 MGI:3621617 NCBI chr 3:155,138,969...155,149,619
Ensembl chr 3:163,190,284...163,199,239
JBrowse link
G SIX2 SIX homeobox 2 involved_in ISO (MGI:4822095|PMID:20515681) UniProt PMID:20515681 MGI:4822095 NCBI chr2A:45,109,414...45,113,887
Ensembl chr2A:46,039,582...46,044,035
JBrowse link
G TRPS1 transcriptional repressor GATA binding 1 involved_in ISO (MGI:3848565|PMID:19389374) UniProt PMID:19389374 MGI:3848565 NCBI chr 8:112,079,147...112,339,567 JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (PMID:90087) MGI PMID:90087 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
JBrowse link
G RFLNA refilin A acts_upstream_of_or_within ISO (MGI:5570967|PMID:24436304) MGI PMID:24436304 MGI:5570967 NCBI chr12:121,737,946...121,903,635
Ensembl chr12:126,164,592...126,191,071
JBrowse link
G RFLNB refilin B acts_upstream_of_or_within ISO (MGI:5570967|PMID:24436304) MGI PMID:24436304 MGI:5570967 NCBI chr17:359,016...367,464
Ensembl chr17:375,885...381,580
JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 involved_in ISO (PMID:22247065) BHF-UCL PMID:22247065 NCBI chr 5:76,442,053...76,818,726
Ensembl chr 5:81,827,560...82,199,840
JBrowse link
G BMP4 bone morphogenetic protein 4 acts_upstream_of_or_within ISO (MGI:3714677|PMID:17481601) MGI PMID:17481601 MGI:3714677 NCBI chr14:34,542,132...34,549,286
Ensembl chr14:52,821,872...52,828,752
JBrowse link
G CCN4 cellular communication network factor 4 involved_in ISO (MGI:6294593|PMID:15331410) UniProt PMID:15331410 MGI:6294593 NCBI chr 8:129,842,580...129,884,528
Ensembl chr 8:132,818,397...132,858,861
JBrowse link
G CHADL chondroadherin like involved_in ISO (MGI:5617405|PMID:25451920) UniProt PMID:25451920 MGI:5617405 NCBI chr22:22,106,953...22,138,122 JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of_or_within ISO (MGI:3701031|PMID:16818445) MGI PMID:16818445 MGI:3701031 NCBI chr 3:41,104,940...41,145,934
Ensembl chr 3:41,373,726...41,414,030
JBrowse link
G EFEMP1 EGF containing fibulin extracellular matrix protein 1 involved_in ISO (PMID:20005202) UniProt PMID:20005202 NCBI chr2A:56,017,678...56,076,059
Ensembl chr2A:57,155,000...57,212,500
JBrowse link
G GDF5 growth differentiation factor 5 involved_in ISO (PMID:21976273) UniProt PMID:21976273 NCBI chr20:31,761,199...31,766,229
Ensembl chr20:32,882,094...32,886,899
JBrowse link
G GLI2 GLI family zinc finger 2 acts_upstream_of_or_within ISO (MGI:3709778|PMID:17328886) MGI PMID:17328886 MGI:3709778 NCBI chr2B:7,665,403...7,922,840
Ensembl chr2B:121,303,831...121,497,442
JBrowse link
G GREM1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:10556075) AgBase PMID:10556075 NCBI chr15:11,213,870...11,230,619 JBrowse link
G LOC100976854 A disintegrin and metalloproteinase with thrombospondin motifs 7 involved_in ISO (PMID:22247065) BHF-UCL PMID:22247065 Ensembl chr15:76,692,416...76,735,344 JBrowse link
G LTBP3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO (MGI:2178869|PMID:11790802) MGI PMID:11790802 MGI:2178869 NCBI chr11:60,897,897...60,917,690
Ensembl chr11:64,233,504...64,252,802
JBrowse link
G MKX mohawk homeobox ISO RGD PMID:27370800 RGD:40924660 NCBI chr10:27,820,454...27,893,373
Ensembl chr10:28,181,483...28,254,311
JBrowse link
G NKX3-2 NK3 homeobox 2 involved_in ISO (MGI:3617032|PMID:16421188) UniProt PMID:16421188 MGI:3617032 NCBI chr 4:7,958,218...7,961,844
Ensembl chr 4:13,258,949...13,262,458
JBrowse link
G PTH parathyroid hormone involved_in ISO PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr11:13,653,777...13,657,901
Ensembl chr11:13,347,838...13,351,802
JBrowse link
G PTHLH parathyroid hormone like hormone acts_upstream_of_or_within ISO (MGI:3709778|PMID:17328886)
(PMID:90087)
(MGI:1352921|PMID:8895385)
MGI PMID:90087 PMID:8895385 PMID:17328886 MGI:1352921 MGI:3709778 NCBI chr12:58,341,361...58,355,804
Ensembl chr12:60,960,071...60,973,750
JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in ISO (MGI:6414736|PMID:29644115) UniProt PMID:29644115 MGI:6414736 NCBI chr12:110,016,364...110,107,462
Ensembl chr12:113,435,669...113,503,762
JBrowse link
G RARB retinoic acid receptor beta acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) MGI PMID:10684250 MGI:1353721 NCBI chr 3:24,729,220...25,499,187
Ensembl chr 3:25,660,922...25,833,297
JBrowse link
G RARG retinoic acid receptor gamma acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) MGI PMID:10684250 MGI:1353721 NCBI chr12:35,521,276...35,542,814
Ensembl chr12:36,303,359...36,325,111
JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in ISO (PMID:19756381) BHF-UCL PMID:19756381 NCBI chr 8:45,341,857...45,345,544
Ensembl chr 8:42,723,971...42,730,904
JBrowse link
G SOX9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO (MGI:2135696|PMID:11371614) MGI PMID:11371614 MGI:2135696 NCBI chr17:66,028,737...66,034,122 JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 involved_in ISO (MGI:3848261|PMID:19494318) BHF-UCL PMID:19494318 MGI:3848261 NCBI chr 9:70,195,007...70,243,514
Ensembl chr 9:98,332,739...98,362,748
JBrowse link
G WNT9A Wnt family member 9A acts_upstream_of_or_within ISO (MGI:3701031|PMID:16818445) MGI PMID:16818445 MGI:3701031 NCBI chr 1:203,320,990...203,350,599
Ensembl chr 1:208,300,609...208,327,191
JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP6 bone morphogenetic protein 6 ISO RGD PMID:23077084 RGD:7242190 NCBI chr 6:7,564,164...7,720,341
Ensembl chr 6:7,848,249...8,000,649
JBrowse link
G FGF18 fibroblast growth factor 18 acts_upstream_of_or_within ISO (MGI:3584218|PMID:15781473) MGI PMID:15781473 MGI:3584218 NCBI chr 5:166,765,061...166,802,277 JBrowse link
G GDF5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within
ISO (PMID:21976273), (PMID:24098149)
(MGI:1329266|PMID:9885252)
(MGI:3819026|PMID:18363966)
UniProt
MGI
PMID:9885252 PMID:18363966 PMID:21976273 PMID:24098149 MGI:1329266 MGI:3819026 NCBI chr20:31,761,199...31,766,229
Ensembl chr20:32,882,094...32,886,899
JBrowse link
G GDF6 growth differentiation factor 6 involved_in ISO (PMID:26643732) UniProt PMID:26643732 NCBI chr 8:92,767,401...92,785,955 JBrowse link
G GLI3 GLI family zinc finger 3 acts_upstream_of_or_within ISO (MGI:3709778|PMID:17328886) MGI PMID:17328886 MGI:3709778 NCBI chr 7:42,004,965...42,280,772
Ensembl chr 7:42,056,565...42,322,865
JBrowse link
G HOXA11 homeobox A11 acts_upstream_of_or_within ISO (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr 7:27,826,003...27,829,757
Ensembl chr 7:27,424,759...27,429,103
JBrowse link
G HOXD11 homeobox D11 acts_upstream_of_or_within ISO (MGI:3043491|PMID:14668414) MGI PMID:14668414 MGI:3043491 NCBI chr2B:63,386,806...63,398,777 JBrowse link
G LOC100990437 NADPH--cytochrome P450 reductase ISO RGD PMID:19264869 RGD:2316785 NCBI chr 7:68,035,021...68,105,934
Ensembl chr 7:82,364,418...82,437,530
JBrowse link
G LOXL2 lysyl oxidase like 2 involved_in ISO (MGI:5320274|PMID:21071451) UniProt PMID:21071451 MGI:5320274 NCBI chr 8:22,547,303...22,653,676
Ensembl chr 8:19,483,335...19,589,522
JBrowse link
G MUSTN1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) MGI PMID:19410023 MGI:5703727 NCBI chr 3:52,774,843...52,778,280
Ensembl chr 3:54,000,547...54,004,099
JBrowse link
G PKDCC protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) UniProt PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr2A:42,146,153...42,156,652 JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO RGD PMID:17884819 RGD:2298851 NCBI chr11:61,012,839...61,022,225
Ensembl chr11:64,347,859...64,356,868
JBrowse link
G RUNX2 RUNX family transcription factor 2 acts_upstream_of_or_within ISO (MGI:1332911|PMID:10072783) MGI PMID:10072783 MGI:1332911 NCBI chr 6:45,003,962...45,133,148
Ensembl chr 6:46,189,432...46,524,389
JBrowse link
G SMAD3 SMAD family member 3 involved_in ISO (MGI:5285145|PMID:21035443) UniProt PMID:21035443 MGI:5285145 NCBI chr15:46,013,764...46,143,126
Ensembl chr15:64,284,949...64,414,185
JBrowse link
G SOX5 SRY-box transcription factor 5 involved_in ISO (PMID:21401405)
(MGI:5285147|PMID:20940257)
UniProt PMID:20940257 PMID:21401405 MGI:5285147 NCBI chr12:62,361,631...62,780,805
Ensembl chr12:64,971,818...65,388,694
JBrowse link
G SOX6 SRY-box transcription factor 6 involved_in ISO (PMID:21401405)
(MGI:5285147|PMID:20940257)
UniProt PMID:20940257 PMID:21401405 MGI:5285147 NCBI chr11:16,053,730...16,488,566
Ensembl chr11:15,747,495...16,175,246
JBrowse link
G SOX9 SRY-box transcription factor 9 involved_in ISO (PMID:20676705)
(MGI:4950303|PMID:21367821)
(MGI:5285147|PMID:20940257)
(PMID:21401405)
UniProt PMID:20676705 PMID:20940257 PMID:21367821 PMID:21401405 MGI:4950303 MGI:5285147 NCBI chr17:66,028,737...66,034,122 JBrowse link
G THRB thyroid hormone receptor beta ISO RGD PMID:15647824 RGD:1601663 NCBI chr 3:24,024,025...24,401,024
Ensembl chr 3:24,346,824...24,564,960
JBrowse link
G ZBTB16 zinc finger and BTB domain containing 16 involved_in ISO (PMID:21547890) UniProt PMID:21547890 NCBI chr11:108,938,414...109,133,819
Ensembl chr11:112,780,380...112,977,164
JBrowse link
G ZNF219 zinc finger protein 219 involved_in ISO (MGI:5285147|PMID:20940257) UniProt PMID:20940257 MGI:5285147 NCBI chr14:1,904,632...1,919,304
Ensembl chr14:19,986,653...20,000,300
JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD7 SMAD family member 7 involved_in ISO (MGI:6377914|PMID:29503843) CACAO PMID:29503843 MGI:6377914 NCBI chr18:42,306,324...42,337,214 JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AXIN2 axin 2 acts_upstream_of_or_within ISO (MGI:4818263|PMID:19623616) MGI PMID:19623616 MGI:4818263 NCBI chr17:59,476,336...59,509,358
Ensembl chr17:64,688,416...64,720,086
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12786
    developmental process 5966
      regulation of developmental process 2464
        regulation of cell differentiation 1576
          regulation of chondrocyte differentiation 54
            negative regulation of chondrocyte differentiation + 24
            positive regulation of chondrocyte differentiation + 21
            regulation of chondrocyte development + 5
            regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 12786
    developmental process 5966
      anatomical structure development 5565
        multicellular organism development 5084
          system development 4765
            animal organ development 3685
              cartilage development 213
                regulation of cartilage development 72
                  regulation of chondrocyte differentiation 54
                    negative regulation of chondrocyte differentiation + 24
                    positive regulation of chondrocyte differentiation + 21
                    regulation of chondrocyte development + 5
                    regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
paths to the root