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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of chondrocyte differentiation
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Accession:GO:0032330 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of chondrocyte differentiation.



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regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 acts_upstream_of_or_within ISO MGI:2663631 (MGI:4413658|PMID:18597638) RGD PMID:18597638 MGI:4413658 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:4829764 (MGI:4829577|PMID:20530870)
Ensembl
RGD
PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (MGI:5462316|PMID:22916278) RGD PMID:22916278 MGI:5462316 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (MGI:5462316|PMID:22916278) RGD PMID:22916278 MGI:5462316 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783
JBrowse link
G Lnpk lunapark, ER junction formation factor acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) RGD PMID:22916278 MGI:5462316 NCBI chr 3:59,418,872...59,487,029
Ensembl chr 3:59,424,286...59,486,518
JBrowse link
G Maf MAF bZIP transcription factor involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2148636 (MGI:2676505|PMID:14512017)
Ensembl
RGD
PMID:14512017 GO_REF:0000107 MGI:2676505 NCBI chr19:43,353,867...43,713,162
Ensembl chr19:43,360,342...43,712,365
JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:6467698|PMID:29196633)
UniProt
RGD
PMID:29196633 GO_REF:0000024 MGI:6467698 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485
JBrowse link
G Mdk midkine involved_in ISS
ISO
GO_REF:0000024
(MGI:5693192|PMID:25551381)
UniProt
RGD
PMID:25551381 GO_REF:0000024 MGI:5693192 NCBI chr 3:77,901,156...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Prkg2 protein kinase cGMP-dependent 2 IGI RGD PMID:15466490 RGD:150429792 NCBI chr14:10,559,882...10,668,479
Ensembl chr14:10,559,882...10,666,888
JBrowse link
G Pthlh parathyroid hormone-like hormone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Shox2 short stature homeobox 2 acts_upstream_of_or_within
involved_in
ISO
IEA
MGI:3628798 (MGI:3621617|PMID:16537395)
GO_REF:0000107
RGD
Ensembl
PMID:16537395 GO_REF:0000107 MGI:3621617 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143
JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:4822095|PMID:20515681) RGD PMID:20515681 MGI:4822095 NCBI chr 6:8,974,859...8,981,345
Ensembl chr 6:8,967,157...8,981,193
JBrowse link
G Trps1 transcriptional repressor GATA binding 1 involved_in ISO (MGI:3848565|PMID:19389374) RGD PMID:19389374 MGI:3848565 NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905
JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO (PMID:90087) RGD PMID:90087 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Rflna refilin A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1923816 (MGI:5570967|PMID:24436304)
RGD PMID:24436304 PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr12:31,633,361...31,642,317
Ensembl chr12:31,633,361...31,642,317
JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:1920371 (MGI:5570967|PMID:24436304)
RGD PMID:24436304 PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976
JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:22247065) RGD PMID:22247065 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629
JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 involved_in ISO (PMID:22247065) RGD PMID:22247065 NCBI chr 8:90,704,727...90,744,331
Ensembl chr 8:90,704,727...90,744,328
JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3714677|PMID:17481601)
Ensembl
RGD
PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306
JBrowse link
G Ccn4 cellular communication network factor 4 involved_in IEA
ISO
GO_REF:0000107
(MGI:6294593|PMID:15331410)
Ensembl
RGD
PMID:15331410 GO_REF:0000107 MGI:6294593 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
JBrowse link
G Chadl chondroadherin-like involved_in ISO (MGI:5617405|PMID:25451920) RGD PMID:25451920 MGI:5617405 NCBI chr 7:113,205,323...113,218,678
Ensembl chr 7:113,210,748...113,217,272
JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2446084 (MGI:3701031|PMID:16818445)
Ensembl
RGD
PMID:16818445 GO_REF:0000107 MGI:3701031 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 involved_in ISO
IEA
ISS
(PMID:20005202)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:20005202 GO_REF:0000024 GO_REF:0000107 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Gdf5 growth differentiation factor 5 involved_in ISO (PMID:21976273) RGD PMID:21976273 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr13:29,946,809...30,163,901
Ensembl chr13:29,946,809...30,163,574
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:10556075) RGD PMID:10556075 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082
JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (MGI:2178869|PMID:11790802) RGD PMID:11790802 MGI:2178869 NCBI chr 1:203,029,412...203,045,975
Ensembl chr 1:203,029,877...203,045,975
JBrowse link
G Mkx mohawk homeobox IMP RGD PMID:27370800 RGD:40924660 NCBI chr17:55,077,073...55,156,877
Ensembl chr17:55,077,540...55,156,124
JBrowse link
G Nkx3-2 NK3 homeobox 2 involved_in ISO (MGI:3617032|PMID:16421188) RGD PMID:16421188 MGI:3617032 NCBI chr14:69,183,795...69,186,182
Ensembl chr14:69,183,820...69,186,061
JBrowse link
G Pth parathyroid hormone involved_in IMP PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515|MGI:95728 (MGI:1352921|PMID:8895385), (MGI:3709778|PMID:17328886)
(PMID:90087)
RGD PMID:90087 PMID:8895385 PMID:17328886 MGI:1352921 MGI:3709778 NCBI chr 4:180,188,792...180,199,847
Ensembl chr 4:180,188,792...180,199,847
JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414736|PMID:29644115)
UniProt
RGD
PMID:29644115 GO_REF:0000024 MGI:6414736 NCBI chr12:35,365,436...35,424,925
Ensembl chr12:35,383,144...35,424,925
JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) RGD PMID:10684250 MGI:1353721 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) RGD PMID:10684250 MGI:1353721 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:19756381) RGD PMID:19756381 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
MGI:2158693 (MGI:2135696|PMID:11371614)
UniProt
RGD
PMID:11371614 GO_REF:0000024 MGI:2135696 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO
IEA
(MGI:3848261|PMID:19494318)
GO_REF:0000107
RGD
Ensembl
PMID:19494318 GO_REF:0000107 MGI:3848261 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350|MGI:88276 (MGI:3701031|PMID:16818445) RGD PMID:16818445 MGI:3701031 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133
JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 IDA RGD PMID:23077084 RGD:7242190 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:95524 (MGI:3584218|PMID:15781473)
Ensembl
RGD
PMID:15781473 GO_REF:0000107 MGI:3584218 NCBI chr10:17,706,011...17,737,702
Ensembl chr10:17,706,174...17,736,818
JBrowse link
G Gdf5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within
ISO (PMID:21976273), (PMID:24098149)
MGI:1927616 (MGI:1329266|PMID:9885252), (MGI:3819026|PMID:18363966)
RGD PMID:9885252 PMID:18363966 PMID:21976273 PMID:24098149 MGI:1329266 MGI:3819026 NCBI chr 3:144,454,306...144,458,757
Ensembl chr 3:144,454,338...144,458,612
JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO
ISS
(PMID:26643732)
GO_REF:0000024
RGD
UniProt
PMID:26643732 GO_REF:0000024 NCBI chr 5:22,996,246...23,012,567
Ensembl chr 5:22,996,246...23,012,567
JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:1856276 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr17:49,438,567...49,709,712
Ensembl chr17:49,438,567...49,709,712
JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783
JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISO
ISS
GO_REF:0000107
(MGI:5320274|PMID:21071451)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:21071451 GO_REF:0000024 GO_REF:0000107 MGI:5320274 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067
JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,072,908...6,075,158
Ensembl chr16:6,072,833...6,075,161
JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) RGD PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr 6:11,455,686...11,465,002
Ensembl chr 6:11,455,686...11,465,556
JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:17884819 RGD:2298851 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:2176465 (MGI:1332911|PMID:10072783)
Ensembl
RGD
PMID:10072783 GO_REF:0000107 MGI:1332911 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (MGI:5285145|PMID:21035443) RGD PMID:21035443 MGI:5285145 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO
IBA
(PMID:21401405)
(MGI:5285147|PMID:20940257)
PMID:21873635
RGD PMID:20940257 PMID:21401405 PMID:21873635 MGI:5285147, RGD:13792537 NCBI chr 4:176,781,375...177,736,833
Ensembl chr 4:176,785,892...177,736,852
JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IBA
(PMID:21401405)
(MGI:5285147|PMID:20940257)
PMID:21873635
RGD PMID:20940257 PMID:21401405 PMID:21873635 MGI:5285147, RGD:13792537 NCBI chr 1:169,723,306...170,334,846
Ensembl chr 1:169,729,194...170,277,386
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO
ISS
IBA
(PMID:20676705), (PMID:21401405)
(MGI:4950303|PMID:21367821), (MGI:5285147|PMID:20940257)
GO_REF:0000024
PMID:21873635
RGD
UniProt
PMID:20676705 PMID:20940257 PMID:21367821 PMID:21401405 PMID:21873635 GO_REF:0000024 MGI:4950303 MGI:5285147, RGD:13792537 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
G Thrb thyroid hormone receptor beta IDA RGD PMID:15647824 RGD:1601663 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS
(PMID:21547890)
GO_REF:0000024
RGD
UniProt
PMID:21547890 GO_REF:0000024 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zfp219 zinc finger protein 219 involved_in ISO (MGI:5285147|PMID:20940257) RGD PMID:20940257 MGI:5285147 NCBI chr15:24,695,831...24,710,039
Ensembl chr15:24,695,837...24,710,030
JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO
GO_REF:0000107
(MGI:6377914|PMID:29503843)
Ensembl
RGD
PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:3579503 (MGI:4818263|PMID:19623616)
Ensembl
RGD
PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      regulation of developmental process 2717
        regulation of cell differentiation 1730
          regulation of chondrocyte differentiation 54
            negative regulation of chondrocyte differentiation + 24
            positive regulation of chondrocyte differentiation + 21
            regulation of chondrocyte development + 5
            regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 19834
    developmental process 6965
      anatomical structure development 6376
        multicellular organism development 5800
          system development 5439
            animal organ development 4194
              cartilage development 221
                regulation of cartilage development 73
                  regulation of chondrocyte differentiation 54
                    negative regulation of chondrocyte differentiation + 24
                    positive regulation of chondrocyte differentiation + 21
                    regulation of chondrocyte development + 5
                    regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
paths to the root