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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of chondrocyte differentiation
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Accession:GO:0032330 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of chondrocyte differentiation.

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regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccn2 cellular communication network factor 2 acts_upstream_of_or_within ISO MGI:2663631 (MGI:4413658|PMID:18597638) RGD PMID:18597638 MGI:4413658 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773 		JBrowse link
G Glg1 golgi glycoprotein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4829764 (MGI:4829577|PMID:20530870)		 Ensembl
RGD		 PMID:20530870 GO_REF:0000107 MGI:4829577 NCBI chr19:42,983,879...43,088,074
Ensembl chr19:42,983,869...43,090,841 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (MGI:5462316|PMID:22916278) RGD PMID:22916278 MGI:5462316 NCBI chr 4:82,296,888...82,301,419
Ensembl chr 4:82,298,152...82,300,503
Ensembl chr 4:82,298,152...82,300,503 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (MGI:5462316|PMID:22916278) RGD PMID:22916278 MGI:5462316 NCBI chr 3:61,604,256...61,606,874
Ensembl chr 3:61,604,672...61,606,400 		JBrowse link
G Lnpk lunapark, ER junction formation factor acts_upstream_of_or_within ISO (MGI:5462316|PMID:22916278) RGD PMID:22916278 MGI:5462316 NCBI chr 3:61,432,128...61,494,828
Ensembl chr 3:61,433,863...61,494,778 		JBrowse link
G Maf MAF bZIP transcription factor involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2148636 (MGI:2676505|PMID:14512017)		 Ensembl
RGD		 PMID:14512017 GO_REF:0000107 MGI:2676505 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6467698|PMID:29196633)		 UniProt
RGD		 PMID:29196633 GO_REF:0000024 MGI:6467698 NCBI chr 6:44,009,872...44,135,501
Ensembl chr 6:44,009,872...44,131,387 		JBrowse link
G Mdk midkine involved_in ISS
ISO		 GO_REF:0000024
(MGI:5693192|PMID:25551381)		 UniProt
RGD		 PMID:25551381 GO_REF:0000024 MGI:5693192 NCBI chr 3:80,841,003...80,843,895
Ensembl chr 3:80,841,005...80,842,916 		JBrowse link
G Pthlh parathyroid hormone-like hormone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Shox2 short stature homeobox 2 acts_upstream_of_or_within ISO MGI:3628798 (MGI:3621617|PMID:16537395) RGD PMID:16537395 MGI:3621617 NCBI chr 2:164,118,175...164,126,783
Ensembl chr 2:164,118,191...164,126,783 		JBrowse link
G Six2 SIX homeobox 2 involved_in ISO (MGI:4822095|PMID:20515681) RGD PMID:20515681 MGI:4822095 NCBI chr 6:8,952,572...8,955,893
Ensembl chr 6:8,952,572...8,956,276 		JBrowse link
G Trps1 transcriptional repressor GATA binding 1 involved_in ISO (MGI:3848565|PMID:19389374) RGD PMID:19389374 MGI:3848565 NCBI chr 7:90,085,895...90,320,430
Ensembl chr 7:90,090,828...90,318,221 		JBrowse link
negative regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rflna refilin A involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1923816 (MGI:5570967|PMID:24436304)		 RGD PMID:24436304, PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr12:37,038,732...37,047,628
Ensembl chr12:37,038,733...37,047,628 		JBrowse link
G Rflnb refilin B involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
MGI:1920371 (MGI:5570967|PMID:24436304)		 RGD PMID:24436304, PMID:21873635 MGI:5570967, RGD:13792537 NCBI chr10:64,196,103...64,202,380
Ensembl chr10:64,196,127...64,202,380 		JBrowse link
negative regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 involved_in ISO (PMID:22247065) RGD PMID:22247065 NCBI chr 2:61,039,072...61,340,687
Ensembl chr 2:61,039,053...61,340,697 		JBrowse link
G Adamts7 ADAM metallopeptidase with thrombospondin type 1 motif, 7 involved_in ISO (PMID:22247065) RGD PMID:22247065 NCBI chr 8:97,535,777...97,575,661
Ensembl chr 8:97,535,777...97,575,655 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3714677|PMID:17481601)		 Ensembl
RGD		 PMID:17481601 GO_REF:0000107 MGI:3714677 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Ccn4 cellular communication network factor 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6294593|PMID:15331410)		 Ensembl
RGD		 PMID:15331410 GO_REF:0000107 MGI:6294593 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772 		JBrowse link
G Chadl chondroadherin-like involved_in ISO (MGI:5617405|PMID:25451920) RGD PMID:25451920 MGI:5617405 NCBI chr 7:122,915,847...122,929,127
Ensembl chr 7:122,922,022...122,926,336 		JBrowse link
G Ctnnb1 catenin beta 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2446084 (MGI:3701031|PMID:16818445)		 Ensembl
RGD		 PMID:16818445 GO_REF:0000107 MGI:3701031 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 involved_in ISO
IEA
ISS		 (PMID:20005202)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:20005202 GO_REF:0000024 GO_REF:0000107 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in ISO (PMID:21976273) RGD PMID:21976273 NCBI chr 3:151,482,672...151,487,129
Ensembl chr 3:151,483,249...151,486,693 		JBrowse link
G Gli2 GLI family zinc finger 2 acts_upstream_of_or_within ISO MGI:1857509 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr13:34,829,021...35,049,172
Ensembl chr13:34,829,139...35,048,444 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist involved_in ISO (PMID:10556075) RGD PMID:10556075 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989 		JBrowse link
G Ltbp3 latent transforming growth factor beta binding protein 3 acts_upstream_of_or_within ISO MGI:2180017 (MGI:2178869|PMID:11790802) RGD PMID:11790802 MGI:2178869 NCBI chr 1:221,099,155...221,116,096
Ensembl chr 1:221,099,998...221,116,096 		JBrowse link
G Mkx mohawk homeobox IMP RGD PMID:27370800 RGD:40924660 NCBI chr17:60,537,615...60,553,284
Ensembl chr17:60,537,935...60,549,750 		JBrowse link
G Nkx3-2 NK3 homeobox 2 involved_in ISO (MGI:3617032|PMID:16421188) RGD PMID:16421188 MGI:3617032 NCBI chr14:73,813,531...73,818,489
Ensembl chr14:73,813,528...73,815,757 		JBrowse link
G Pth parathyroid hormone involved_in IMP PMID:11604398 CAFA PMID:11604398 RGD:12793028 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761 		JBrowse link
G Pthlh parathyroid hormone-like hormone acts_upstream_of_or_within ISO MGI:2154515|MGI:95728 (MGI:1352921|PMID:8895385), (MGI:3709778|PMID:17328886) RGD PMID:8895385 PMID:17328886 MGI:1352921 MGI:3709778 NCBI chr 4:181,663,425...181,674,181 JBrowse link
G Ptpn11 protein tyrosine phosphatase, non-receptor type 11 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6414736|PMID:29644115)		 UniProt
RGD		 PMID:29644115 GO_REF:0000024 MGI:6414736 NCBI chr12:40,895,515...40,955,999
Ensembl chr12:40,895,515...40,955,999 		JBrowse link
G Rarb retinoic acid receptor, beta acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) RGD PMID:10684250 MGI:1353721 NCBI chr15:9,915,223...10,262,599
Ensembl chr15:10,120,206...10,262,599 		JBrowse link
G Rarg retinoic acid receptor, gamma acts_upstream_of_or_within ISO (MGI:1353721|PMID:10684250) RGD PMID:10684250 MGI:1353721 NCBI chr 7:143,840,739...143,863,206
Ensembl chr 7:143,839,980...143,863,186 		JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:19756381) RGD PMID:19756381 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2158693 (MGI:2135696|PMID:11371614)		 UniProt
RGD		 PMID:11371614 GO_REF:0000024 MGI:2135696 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 involved_in ISO (MGI:3848261|PMID:19494318) RGD PMID:19494318 MGI:3848261 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635 		JBrowse link
G Wnt9a Wnt family member 9A acts_upstream_of_or_within ISO MGI:3701350|MGI:88276 (MGI:3701031|PMID:16818445) RGD PMID:16818445 MGI:3701031 NCBI chr10:45,659,045...45,686,103
Ensembl chr10:45,659,143...45,681,393 		JBrowse link
positive regulation of chondrocyte differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp6 bone morphogenetic protein 6 IDA RGD PMID:23077084 RGD:7242190 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820 		JBrowse link
G Fgf18 fibroblast growth factor 18 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:95524 (MGI:3584218|PMID:15781473)		 Ensembl
RGD		 PMID:15781473 GO_REF:0000107 MGI:3584218 NCBI chr10:18,047,109...18,082,290
Ensembl chr10:18,047,109...18,063,391 		JBrowse link
G Gdf5 growth differentiation factor 5 involved_in
acts_upstream_of_or_within		 ISO (PMID:21976273), (PMID:24098149)
MGI:1927616 (MGI:1329266|PMID:9885252), (MGI:3819026|PMID:18363966)		 RGD PMID:9885252 PMID:18363966 PMID:21976273 PMID:24098149 MGI:1329266 MGI:3819026 NCBI chr 3:151,482,672...151,487,129
Ensembl chr 3:151,483,249...151,486,693 		JBrowse link
G Gdf6 growth differentiation factor 6 involved_in ISO
ISS		 (PMID:26643732)
GO_REF:0000024		 RGD
UniProt		 PMID:26643732 GO_REF:0000024 NCBI chr 5:23,056,345...23,072,666
Ensembl chr 5:23,056,347...23,074,599 		JBrowse link
G Gli3 GLI family zinc finger 3 acts_upstream_of_or_within ISO MGI:1856276 (MGI:3709778|PMID:17328886) RGD PMID:17328886 MGI:3709778 NCBI chr17:52,294,942...52,569,036
Ensembl chr17:52,294,942...52,569,036 		JBrowse link
G Hoxa11 homeobox A11 acts_upstream_of_or_within ISO MGI:96203 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 4:82,296,888...82,301,419
Ensembl chr 4:82,298,152...82,300,503
Ensembl chr 4:82,298,152...82,300,503 		JBrowse link
G Hoxd11 homeobox D11 acts_upstream_of_or_within ISO MGI:96172 (MGI:3043491|PMID:14668414) RGD PMID:14668414 MGI:3043491 NCBI chr 3:61,604,256...61,606,874
Ensembl chr 3:61,604,672...61,606,400 		JBrowse link
G Loxl2 lysyl oxidase-like 2 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5320274|PMID:21071451)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21071451 GO_REF:0000024 GO_REF:0000107 MGI:5320274 NCBI chr15:51,276,022...51,365,238
Ensembl chr15:51,303,909...51,365,234 		JBrowse link
G Mustn1 musculoskeletal, embryonic nuclear protein 1 acts_upstream_of_or_within ISO (MGI:5703727|PMID:19410023) RGD PMID:19410023 MGI:5703727 NCBI chr16:6,962,737...6,964,987
Ensembl chr16:6,962,722...6,964,989 		JBrowse link
G Pkdcc protein kinase domain containing, cytoplasmic involved_in ISO (MGI:3813934|PMID:19097194), (MGI:4438146|PMID:19465597) RGD PMID:19097194 PMID:19465597 MGI:3813934 MGI:4438146 NCBI chr 6:6,427,657...6,436,974
Ensembl chr 6:6,427,657...6,436,974 		JBrowse link
G Por cytochrome p450 oxidoreductase IMP RGD PMID:19264869 RGD:2316785 NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IMP RGD PMID:17884819 RGD:2298851 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249 		JBrowse link
G Runx2 RUNX family transcription factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2176465 (MGI:1332911|PMID:10072783)		 Ensembl
RGD		 PMID:10072783 GO_REF:0000107 MGI:1332911 NCBI chr 9:18,564,743...18,773,092
Ensembl chr 9:18,564,927...18,773,092 		JBrowse link
G Smad3 SMAD family member 3 involved_in ISO (MGI:5285145|PMID:21035443) RGD PMID:21035443 MGI:5285145 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349 		JBrowse link
G Sox5 SRY-box transcription factor 5 involved_in ISO
IBA		 (PMID:21401405)
(MGI:5285147|PMID:20940257)
PMID:21873635		 RGD PMID:20940257 PMID:21401405, PMID:21873635 MGI:5285147, RGD:13792537 NCBI chr 4:178,062,267...179,031,991
Ensembl chr 4:178,066,165...178,441,547 		JBrowse link
G Sox6 SRY-box transcription factor 6 involved_in ISO
IBA		 (PMID:21401405)
(MGI:5285147|PMID:20940257)
PMID:21873635		 RGD PMID:20940257 PMID:21401405, PMID:21873635 MGI:5285147, RGD:13792537 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO
ISS
IBA		 (PMID:20676705), (PMID:21401405)
(MGI:4950303|PMID:21367821), (MGI:5285147|PMID:20940257)
GO_REF:0000024
PMID:21873635		 RGD
UniProt		 PMID:20676705 PMID:20940257 PMID:21367821 PMID:21401405, PMID:21873635 GO_REF:0000024 MGI:4950303 MGI:5285147, RGD:13792537 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379 		JBrowse link
G Thrb thyroid hormone receptor beta IDA RGD PMID:15647824 RGD:1601663 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282 		JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 involved_in ISO
ISS		 (PMID:21547890)
GO_REF:0000024		 RGD
UniProt		 PMID:21547890 GO_REF:0000024 NCBI chr 8:52,980,226...53,146,765
Ensembl chr 8:52,985,313...53,146,953 		JBrowse link
G Zfp219 zinc finger protein 219 involved_in ISO (MGI:5285147|PMID:20940257) RGD PMID:20940257 MGI:5285147 NCBI chr15:28,402,412...28,417,379
Ensembl chr15:28,402,415...28,406,046 		JBrowse link
positive regulation of chondrocyte hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad7 SMAD family member 7 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6377914|PMID:29503843)		 Ensembl
RGD		 PMID:29503843 GO_REF:0000107 MGI:6377914 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157 		JBrowse link
regulation of chondrocyte development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin2 axin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3579503 (MGI:4818263|PMID:19623616)		 Ensembl
RGD		 PMID:19623616 GO_REF:0000107 MGI:4818263 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    developmental process 6777
      regulation of developmental process 2644
        regulation of cell differentiation 1696
          regulation of chondrocyte differentiation 53
            negative regulation of chondrocyte differentiation + 24
            positive regulation of chondrocyte differentiation + 21
            regulation of chondrocyte development + 4
            regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
Path 2
Term Annotations click to browse term
  biological_process 19638
    developmental process 6777
      anatomical structure development 6250
        multicellular organism development 5734
          system development 5280
            animal organ development 4047
              cartilage development 215
                regulation of cartilage development 71
                  regulation of chondrocyte differentiation 53
                    negative regulation of chondrocyte differentiation + 24
                    positive regulation of chondrocyte differentiation + 21
                    regulation of chondrocyte development + 4
                    regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + 0
paths to the root