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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin cofactor biosynthetic process
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Accession:GO:0032324 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: molybdopterin cofactor anabolism;   molybdopterin cofactor synthesis
 related_synonym: molybdopterin cofactor biosynthesis;   molybdopterin cofactor formation
 xref: MetaCyc:Molybdenum-Cofactor-Biosynthesis


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molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPHN gephyrin involved_in ISO (PMID:9990024)
(PMID:26613940)
CAFA
UniProt
PMID:9990024 PMID:26613940 NCBI chr14:47,081,527...47,755,182
Ensembl chr14:66,137,166...66,634,550
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G MOCS1 molybdenum cofactor synthesis 1 acts_upstream_of_or_within ISO (MGI:2447229|PMID:12471057), (MGI:3576970|PMID:15862276), (MGI:3757917|PMID:17236133) MGI PMID:12471057 PMID:15862276 PMID:17236133 MGI:2447229 MGI:3576970 MGI:3757917 NCBI chr 6:39,489,310...39,519,012
Ensembl chr 6:40,799,858...40,829,346
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Path 1
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  biological_process 12650
    metabolic process 7923
      prosthetic group metabolic process 5
        molybdopterin cofactor metabolic process 5
          molybdopterin cofactor biosynthetic process 2
Path 2
Term Annotations click to browse term
  biological_process 12650
    metabolic process 7923
      organic substance metabolic process 7635
        macromolecule metabolic process 6543
          cellular macromolecule metabolic process 5572
            cellular protein metabolic process 3465
              prosthetic group metabolic process 5
                molybdopterin cofactor metabolic process 5
                  molybdopterin cofactor biosynthetic process 2
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