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ONTOLOGY REPORT - ANNOTATIONS

Term:molybdopterin cofactor biosynthetic process
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Accession:GO:0032324 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: molybdopterin cofactor anabolism;   molybdopterin cofactor synthesis
 related_synonym: molybdopterin cofactor biosynthesis;   molybdopterin cofactor formation
 xref: MetaCyc:Molybdenum-Cofactor-Biosynthesis


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molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in ISO (PMID:26613940), (PMID:9990024) RGD PMID:9990024 PMID:26613940 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 acts_upstream_of_or_within ISO MGI:2659140 (MGI:2447229|PMID:12471057), (MGI:3576970|PMID:15862276), (MGI:3757917|PMID:17236133) RGD PMID:12471057 PMID:15862276 PMID:17236133 MGI:2447229 MGI:3576970 MGI:3757917 NCBI chr 9:11,547,533...11,573,935
Ensembl chr 9:11,547,531...11,567,790 		JBrowse link
Mo-molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in
acts_upstream_of_or_within		 IEA
IBA
IDA
ISO		 GO_REF:0000104
PMID:21873635
PMID:23163752
MGI:2182559 (MGI:2182545|PMID:9812897)		 UniProt
RGD		 PMID:9812897 PMID:21873635 PMID:23163752 GO_REF:0000104 MGI:2182545, RGD:13792537, RGD:8554131 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612 		JBrowse link
G Mocos molybdenum cofactor sulfurase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187 		JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 involved_in ISO
IBA		 (PMID:15180982)
PMID:21873635
(PMID:16021469), (PMID:9731530), (PMID:9921896)		 RGD PMID:9731530 PMID:9921896 PMID:15180982 PMID:16021469 PMID:21873635 RGD:13792537 NCBI chr 9:11,547,533...11,573,935
Ensembl chr 9:11,547,531...11,567,790 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 involved_in ISO
ISS		 (PMID:10053004), (PMID:12732628), (PMID:15073332), (PMID:16021469)
GO_REF:0000024		 RGD
UniProt		 PMID:10053004 PMID:12732628 PMID:15073332 PMID:16021469 GO_REF:0000024 NCBI chr 2:46,504,574...46,516,327
Ensembl chr 2:46,504,588...46,516,324 		JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO (PMID:15073332) RGD PMID:15073332 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890 		JBrowse link
G Nfs1 NFS1 cysteine desulfurase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      prosthetic group metabolic process 6
        molybdopterin cofactor metabolic process 6
          molybdopterin cofactor biosynthetic process 6
            Mo-molybdopterin cofactor biosynthetic process + 6
            W-molybdopterin cofactor biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19818
    metabolic process 12096
      organic substance metabolic process 11623
        organonitrogen compound metabolic process 6766
          protein metabolic process 5776
            prosthetic group metabolic process 6
              molybdopterin cofactor metabolic process 6
                molybdopterin cofactor biosynthetic process 6
                  Mo-molybdopterin cofactor biosynthetic process + 6
                  W-molybdopterin cofactor biosynthetic process 0
paths to the root