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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin cofactor biosynthetic process
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Accession:GO:0032324 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: molybdopterin cofactor anabolism;   molybdopterin cofactor synthesis
 related_synonym: molybdopterin cofactor biosynthesis;   molybdopterin cofactor formation
 xref: MetaCyc:Molybdenum-Cofactor-Biosynthesis



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molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in ISO (PMID:26613940), (PMID:9990024)
MGI:2182559 (PMID:12565882), (PMID:18411266)
RGD PMID:9990024 PMID:12565882 PMID:18411266 PMID:26613940 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Mocos molybdenum cofactor sulfurase involved_in ISO (PMID:35372998) RGD PMID:35372998 NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 involved_in
acts_upstream_of_or_within
ISO (PMID:17236133)
MGI:2659140 (PMID:12471057), (PMID:15862276), (PMID:17236133)
RGD PMID:12471057 PMID:15862276 PMID:17236133 NCBI chr 9:11,547,533...11,573,935
Ensembl chr 9:11,547,531...11,567,790
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 involved_in ISO MGI:4881158 (PMID:27138983) RGD PMID:27138983 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324
JBrowse link
Mo-molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
IDA
GO_REF:0000104
MGI:2182559 (PMID:9812897)
GO_REF:0000033
PMID:23163752
UniProt
RGD
GO_Central
PMID:9812897 PMID:23163752 GO_REF:0000033 GO_REF:0000104, RGD:8554131 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Mocos molybdenum cofactor sulfurase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:15,931,659...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 involved_in ISO
IBA
(PMID:15180982)
GO_REF:0000033
(PMID:16021469), (PMID:9731530), (PMID:9921896)
RGD
GO_Central
PMID:9731530 PMID:9921896 PMID:15180982 PMID:16021469 GO_REF:0000033 NCBI chr 9:11,547,533...11,573,935
Ensembl chr 9:11,547,531...11,567,790
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 involved_in ISO
ISS
(PMID:10053004), (PMID:12732628), (PMID:15073332), (PMID:16021469)
GO_REF:0000024
RGD
UniProt
PMID:10053004 PMID:12732628 PMID:15073332 PMID:16021469 GO_REF:0000024 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324
JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO (PMID:15073332), (PMID:30817134) RGD PMID:15073332 PMID:30817134 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890
JBrowse link
G Nfs1 NFS1 cysteine desulfurase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      biosynthetic process 8273
        organonitrogen compound biosynthetic process 2110
          molybdopterin cofactor biosynthetic process 6
            Mo-molybdopterin cofactor biosynthetic process + 6
            W-molybdopterin cofactor biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 19872
    metabolic process 11602
      cellular metabolic process 9669
        phosphorus metabolic process 1885
          phosphate-containing compound metabolic process 1853
            molybdopterin cofactor metabolic process 6
              molybdopterin cofactor biosynthetic process 6
                Mo-molybdopterin cofactor biosynthetic process + 6
                W-molybdopterin cofactor biosynthetic process 0
paths to the root