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ONTOLOGY REPORT - ANNOTATIONS

Term:icosanoid secretion
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Accession:GO:0032309 term browser browse the term
Definition:The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.
Synonyms:exact_synonym: eicosanoid secretion

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arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa1 annexin A1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:2661244|PMID:12553880) MGI
Ensembl		 PMID:12553880 GO_REF:0000107 MGI:2661244 NCBI chrNW_004936503:9,124,314...9,142,372 JBrowse link
G Bdkrb2 bradykinin receptor B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936604:548,844...551,031 JBrowse link
G Drd2 dopamine receptor D2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936612:1,094,686...1,154,149 JBrowse link
G Drd3 dopamine receptor D3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936536:1,580,732...1,616,726 JBrowse link
G Drd4 dopamine receptor D4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936888:468,334...471,254 JBrowse link
G Kiss1r KISS1 receptor ISO RGD PMID:11457843 RGD:1357971 NCBI chrNW_004936588:384,195...387,625 JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor ISO RGD PMID:9291830 RGD:1600299 NCBI chrNW_004936508:3,928,467...3,983,481 JBrowse link
G LOC101966422 neuromedin-U receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936515:10,386,538...10,399,177 JBrowse link
G LOC101968921 angiotensin-converting enzyme involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936541:4,157,847...4,178,156 JBrowse link
G LOC101975825 group IIF secretory phospholipase A2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936474:6,186,604...6,192,621 JBrowse link
G Nmb neuromedin B ISO stimulates RGD PMID:8532598 RGD:1642335 NCBI chrNW_004936483:16,712,382...16,715,397 JBrowse link
G Oc90 otoconin 90 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936470:17,072,435...17,099,520 JBrowse link
G Pla2g12a phospholipase A2 group XIIA involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936563:932,900...948,860 JBrowse link
G Pla2g12b phospholipase A2 group XIIB involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936521:6,072,487...6,096,791 JBrowse link
G Pla2g1b phospholipase A2 group IB NOT|involved_in ISO
IEA		 (PMID:15528384) BHF-UCL
InterPro		 PMID:15528384 GO_REF:0000002 NCBI chrNW_004936668:608,848...616,982 JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936474:6,091,978...6,095,961 JBrowse link
G Pla2g2d phospholipase A2 group IID involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936474:6,167,507...6,172,750 JBrowse link
G Pla2g3 phospholipase A2 group III involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936755:307,166...312,683 JBrowse link
G Pla2g4a phospholipase A2 group IVA acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709446|PMID:17293613) MGI
Ensembl		 PMID:17293613 GO_REF:0000107 MGI:3709446 NCBI chrNW_004936481:3,559,377...3,689,797 JBrowse link
G Pla2g4f phospholipase A2 group IVF acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3709446|PMID:17293613) MGI
Ensembl		 PMID:17293613 GO_REF:0000107 MGI:3709446 NCBI chrNW_004936471:5,439,389...5,454,437 JBrowse link
G Pla2g5 phospholipase A2 group V involved_in ISO
IEA		 RGD
InterPro		 PMID:11106649 GO_REF:0000002 RGD:2303037 NCBI chrNW_004936474:6,131,915...6,150,810 JBrowse link
G Pnpla8 patatin like phospholipase domain containing 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936653:1,470,314...1,499,813 JBrowse link
G Proca1 protein interacting with cyclin A1 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004936538:4,911,915...4,921,281 JBrowse link
negative regulation of arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO RGD PMID:9822642 RGD:13800919 NCBI chrNW_004936640:1,916,711...1,924,823 JBrowse link
G Hrh2 histamine receptor H2 ISO RGD PMID:1313563 RGD:9685527 NCBI chrNW_004936609:624,446...664,049 JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISO (MGI:5297792|PMID:11830583) UniProt PMID:11830583 MGI:5297792 NCBI chrNW_004936469:18,679,840...18,789,655 JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor type 2 ISO RGD PMID:18799632 RGD:2313549 NCBI chrNW_004936479:13,252,678...13,255,570 JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long chain family member 4 involved_in ISO (PMID:21242590) UniProt PMID:21242590 NCBI chrNW_004936499:5,456,985...5,540,115 JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 ISO RGD PMID:11581303 PMID:19474762 RGD:13800898 RGD:13800911 NCBI chrNW_004936640:1,916,711...1,924,823 JBrowse link
positive regulation of arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1b arginine vasopressin receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936557:6,415,544...6,423,863 JBrowse link
G Hrh3 histamine receptor H3 ISO RGD PMID:11130725 RGD:151708734 NCBI chrNW_004936514:9,862,104...9,865,614 JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 involved_in ISO (MGI:5051938|PMID:20844270) BHF-UCL PMID:20844270 MGI:5051938 NCBI chrNW_004936501:2,841,209...2,857,570 JBrowse link
G Mif macrophage migration inhibitory factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:1,207,058...1,208,010 JBrowse link
G Ntsr1 neurotensin receptor 1 ISO RGD PMID:11852105 RGD:9743869 NCBI chrNW_004936514:10,240,990...10,272,859 JBrowse link
G Pla2g6 phospholipase A2 group VI ISO RGD PMID:15576376 PMID:20732873 RGD:6482749 RGD:6482753 NCBI chrNW_004936492:3,011,752...3,060,962 JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936469:18,679,840...18,789,655 JBrowse link
G Sstr4 somatostatin receptor 4 ISO RGD PMID:8175684 RGD:2325010 NCBI chrNW_004936620:2,575,880...2,577,761 JBrowse link
positive regulation of fever generation by positive regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf11a TNF receptor superfamily member 11a involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936497:2,944,841...2,986,113 JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936747:1,255,803...1,288,252 JBrowse link
positive regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 ISO RGD PMID:1324048 RGD:8662308 NCBI chrNW_004936534:885,489...892,292 JBrowse link
G Il1a interleukin 1 alpha ISO RGD PMID:8612624 RGD:7800677 NCBI chrNW_004936783:1,210,715...1,218,315 JBrowse link
G Il1b interleukin 1 beta involved_in ISO (MGI:4413614|PMID:19940926) BHF-UCL PMID:19940926 MGI:4413614 NCBI chrNW_004936783:1,251,678...1,256,807 JBrowse link
G LOC101960864 group 10 secretory phospholipase A2 involved_in ISO (PMID:18511424) BHF-UCL PMID:18511424 NCBI chrNW_004936501:2,841,209...2,857,570 JBrowse link
G Mapk9 mitogen-activated protein kinase 9 ISO RGD PMID:9786861 RGD:2304243 NCBI chrNW_004936739:551,678...602,027 JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3616954|PMID:16269410) MGI
Ensembl		 PMID:16269410 GO_REF:0000107 MGI:3616954 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G P2ry2 purinergic receptor P2Y2 ISO RGD PMID:15840771 RGD:2316683 NCBI chrNW_004936498:2,432,436...2,444,495 JBrowse link
G Pla2g3 phospholipase A2 group III acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:6108995|PMID:28947740) MGI
Ensembl		 PMID:28947740 GO_REF:0000107 MGI:6108995 NCBI chrNW_004936755:307,166...312,683 JBrowse link
G Pla2g4a phospholipase A2 group IVA acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5779244|PMID:26828067) MGI
Ensembl		 PMID:26828067 GO_REF:0000107 MGI:5779244 NCBI chrNW_004936481:3,559,377...3,689,797 JBrowse link
G Ptges prostaglandin E synthase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5779244|PMID:26828067) MGI
Ensembl		 PMID:26828067 GO_REF:0000107 MGI:5779244 NCBI chrNW_004936487:16,959,263...16,968,909 JBrowse link
G Trpv4 transient receptor potential cation channel subfamily V member 4 involved_in ISO (PMID:19790068) AgBase PMID:19790068 NCBI chrNW_004936769:1,424,526...1,447,547 JBrowse link
positive regulation of prostaglandin secretion involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936619:1,207,058...1,208,010 JBrowse link
prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25173977) MGI
Ensembl		 PMID:25173977 GO_REF:0000107 NCBI chrNW_004936472:14,396,986...14,624,597 JBrowse link
G LOC101968976 leptin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936479:15,394,966...15,411,334 JBrowse link
G Nos2 nitric oxide synthase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936538:4,052,277...4,097,051 JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of
involved_in		 ISO
IEA		 (MGI:3616954|PMID:16269410) MGI
Ensembl		 PMID:16269410 GO_REF:0000107 MGI:3616954 NCBI chrNW_004936558:3,106,819...3,149,689 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO (MGI:6501918|PMID:32484881) MGI PMID:32484881 MGI:6501918 NCBI chrNW_004936481:3,821,564...3,828,086 JBrowse link
regulation of arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syk spleen associated tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link
regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:18703674) AgBase PMID:18703674 NCBI chrNW_004936595:919,807...935,367 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    localization 4705
      establishment of localization 4107
        transport 3945
          secretion 1012
            icosanoid secretion 51
              arachidonic acid secretion + 34
              negative regulation of icosanoid secretion + 5
              positive regulation of icosanoid secretion + 20
              prostaglandin secretion + 21
              regulation of icosanoid secretion + 26
Path 2
Term Annotations click to browse term
  biological_process 14973
    localization 4705
      establishment of localization 4107
        transport 3945
          ion transport 1439
            anion transport 464
              organic anion transport 323
                carboxylic acid transport 267
                  icosanoid transport 61
                    icosanoid secretion 51
                      arachidonic acid secretion + 34
                      negative regulation of icosanoid secretion + 5
                      positive regulation of icosanoid secretion + 20
                      prostaglandin secretion + 21
                      regulation of icosanoid secretion + 26
paths to the root