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ONTOLOGY REPORT - ANNOTATIONS

Term:icosanoid secretion
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Accession:GO:0032309 term browser browse the term
Definition:The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.
Synonyms:exact_synonym: eicosanoid secretion


show annotations for term's descendants           Sort by:
arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme involved_in IEA
ISO		 GO_REF:0000107
(PMID:17077303)		 Ensembl
RGD		 PMID:17077303 GO_REF:0000107 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Anxa1 annexin A1 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 PMID:21873635
MGI:2449710 (MGI:2661244|PMID:12553880)
GO_REF:0000107		 RGD
Ensembl		 PMID:12553880 PMID:21873635 GO_REF:0000107 MGI:2661244, RGD:13792537 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Bdkrb2 bradykinin receptor B2 involved_in ISO
IEA		 (PMID:17077303)
GO_REF:0000107		 RGD
Ensembl		 PMID:17077303 GO_REF:0000107 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Drd2 dopamine receptor D2 involved_in ISO (PMID:8301582) RGD PMID:8301582 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 involved_in ISO
IEA		 (PMID:8301582)
GO_REF:0000107		 RGD
Ensembl		 PMID:8301582 GO_REF:0000107 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 involved_in ISO
IEA		 (PMID:7512953)
GO_REF:0000107		 RGD
Ensembl		 PMID:7512953 GO_REF:0000107 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G ENSRNOG00000067664 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr 6:100,679,532...100,680,668 JBrowse link
G Kiss1r KISS1 receptor IDA RGD PMID:11457843 RGD:1357971 NCBI chr 7:9,785,135...9,790,283
Ensembl chr 7:9,785,135...9,788,793 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IDA RGD PMID:9291830 RGD:1600299 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Nmb neuromedin B IDA stimulates RGD PMID:8532598 RGD:1642335 NCBI chr 1:134,869,446...134,875,507
Ensembl chr 1:134,869,446...134,872,190 		JBrowse link
G Nmur2 neuromedin U receptor 2 involved_in ISO
IEA		 (PMID:10887190)
GO_REF:0000107		 RGD
Ensembl		 PMID:10887190 GO_REF:0000107 NCBI chr10:40,166,223...40,182,078
Ensembl chr10:40,166,226...40,182,078 		JBrowse link
G Oc90 otoconin 90 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 7:97,635,890...97,669,416
Ensembl chr 7:97,635,890...97,669,416 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g12a phospholipase A2, group XIIA involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 2:218,436,450...218,452,760
Ensembl chr 2:218,436,513...218,452,740 		JBrowse link
G Pla2g12b phospholipase A2, group XIIB involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr20:27,369,196...27,389,517
Ensembl chr20:27,370,266...27,388,743 		JBrowse link
G Pla2g1b phospholipase A2 group IB NOT|involved_in ISO
IEA		 (PMID:15528384)
GO_REF:0000002		 RGD
InterPro		 PMID:15528384 GO_REF:0000002 NCBI chr12:41,142,193...41,151,967
Ensembl chr12:41,142,200...41,153,226 		JBrowse link
G Pla2g2a phospholipase A2 group IIA involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014 		JBrowse link
G Pla2g2c phospholipase A2, group IIC involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:150,959,365...150,981,388
Ensembl chr 5:150,959,182...150,981,377 		JBrowse link
G Pla2g2d phospholipase A2, group IID involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:151,016,010...151,022,531
Ensembl chr 5:151,018,870...151,022,525 		JBrowse link
G Pla2g2f phospholipase A2, group IIF involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:150,986,788...150,993,175
Ensembl chr 5:150,986,788...150,993,175 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in
acts_upstream_of_or_within		 ISO
IEA		 (MGI:5297793|PMID:10946309)
GO_REF:0000107
(MGI:3709446|PMID:17293613)		 RGD
Ensembl		 PMID:10946309 PMID:17293613 GO_REF:0000107 MGI:3709446 MGI:5297793 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Pla2g4f phospholipase A2, group IVF acts_upstream_of_or_within ISO (MGI:3709446|PMID:17293613) RGD PMID:17293613 MGI:3709446 NCBI chr 3:107,249,053...107,266,201
Ensembl chr 3:107,250,075...107,264,689 		JBrowse link
G Pla2g5 phospholipase A2, group V involved_in IDA
IEA
ISO
IBA		 GO_REF:0000002
(MGI:5297792|PMID:11830583)
PMID:21873635		 InterPro
RGD		 PMID:11830583 PMID:11106649 PMID:21873635 GO_REF:0000002 MGI:5297792, RGD:2303037, RGD:13792537 NCBI chr 5:151,041,339...151,109,433
Ensembl chr 5:151,041,340...151,062,658 		JBrowse link
G Pnpla8 patatin-like phospholipase domain containing 8 involved_in ISO (PMID:10833412), (PMID:15695510) RGD PMID:10833412 PMID:15695510 NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734 		JBrowse link
G Proca1 protein interacting with cyclin A1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr10:63,090,018...63,102,941
Ensembl chr10:63,090,018...63,102,940 		JBrowse link
negative regulation of arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp5pf ATP synthase peripheral stalk subunit F6 IDA RGD PMID:9822642 RGD:13800919 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
G Hrh2 histamine receptor H 2 IDA RGD PMID:1313563 RGD:9685527 NCBI chr17:10,368,355...10,407,791
Ensembl chr17:10,368,298...10,407,631 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISO (MGI:5297792|PMID:11830583) RGD PMID:11830583 MGI:5297792 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
negative regulation of icosanoid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr2 angiotensin II receptor, type 2 IMP RGD PMID:18799632 RGD:2313549 NCBI chr  X:112,119,673...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
negative regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acsl4 acyl-CoA synthetase long-chain family member 4 involved_in ISO (PMID:21242590) RGD PMID:21242590 NCBI chr  X:105,942,794...106,006,573
Ensembl chr  X:105,942,799...106,006,427 		JBrowse link
G Atp5pf ATP synthase peripheral stalk subunit F6 IMP
IDA		 RGD PMID:19474762 PMID:11581303 RGD:13800898, RGD:13800911 NCBI chr11:23,881,594...23,889,581
Ensembl chr11:23,881,592...23,889,119 		JBrowse link
positive regulation of arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Avpr1b arginine vasopressin receptor 1B involved_in ISO
IEA		 (PMID:9322919)
GO_REF:0000107		 RGD
Ensembl		 PMID:9322919 GO_REF:0000107 NCBI chr13:43,046,960...43,057,110
Ensembl chr13:43,046,267...43,057,792 		JBrowse link
G Hrh3 histamine receptor H3 IDA RGD PMID:11130725 RGD:151708734 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:4437204|PMID:10364264) RGD PMID:10364264 MGI:4437204 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11852105 RGD:9743869 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in IEA
ISO		 GO_REF:0000107
(MGI:5051938|PMID:20844270)		 Ensembl
RGD		 PMID:20844270 GO_REF:0000107 MGI:5051938 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g6 phospholipase A2 group VI IMP
IDA		 RGD PMID:20732873 PMID:15576376 RGD:6482749, RGD:6482753 NCBI chr 7:110,851,378...110,891,557
Ensembl chr 7:110,851,378...110,891,114 		JBrowse link
G Pla2r1 phospholipase A2 receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5297793|PMID:10946309)		 UniProt
RGD		 PMID:10946309 GO_REF:0000024 MGI:5297793 NCBI chr 3:44,883,943...45,013,793
Ensembl chr 3:44,883,943...45,013,660 		JBrowse link
G Sstr4 somatostatin receptor 4 IDA RGD PMID:8175684 RGD:2325010 NCBI chr 3:135,854,826...135,856,689
Ensembl chr 3:135,854,826...135,856,689 		JBrowse link
positive regulation of fever generation by positive regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tnfrsf11a TNF receptor superfamily member 11A involved_in ISO (MGI:4413614|PMID:19940926) RGD PMID:19940926 MGI:4413614 NCBI chr13:21,928,370...21,986,719
Ensembl chr13:21,928,408...21,986,695 		JBrowse link
G Tnfsf11 TNF superfamily member 11 involved_in ISO
IEA		 (MGI:4413614|PMID:19940926)
GO_REF:0000107		 RGD
Ensembl		 PMID:19940926 GO_REF:0000107 MGI:4413614 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
positive regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 IDA RGD PMID:1324048 RGD:8662308 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Il1a interleukin 1 alpha IDA RGD PMID:8612624 RGD:7800677 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO
IEA		 (MGI:4413614|PMID:19940926)
GO_REF:0000107		 RGD
Ensembl		 PMID:19940926 GO_REF:0000107 MGI:4413614 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 IMP RGD PMID:12649265 RGD:7495834 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 IMP RGD PMID:9786861 RGD:2304243 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide IDA RGD PMID:9575824 RGD:2304227 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (MGI:3616954|PMID:16269410) RGD PMID:16269410 MGI:3616954 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G P2ry2 purinergic receptor P2Y2 IDA RGD PMID:15840771 RGD:2316683 NCBI chr 1:155,352,050...155,367,423
Ensembl chr 1:155,351,165...155,367,632 		JBrowse link
G Pla2g10 phospholipase A2, group X involved_in ISO (PMID:18511424) RGD PMID:18511424 NCBI chr10:1,597,761...1,610,822
Ensembl chr10:1,597,761...1,609,000 		JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (MGI:6108995|PMID:28947740) RGD PMID:28947740 MGI:6108995 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
G Pla2g4a phospholipase A2 group IVA acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2385582 (MGI:5779244|PMID:26828067)
GO_REF:0000107		 RGD
Ensembl		 PMID:26828067 GO_REF:0000107 MGI:5779244 NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266 		JBrowse link
G Ptges prostaglandin E synthase acts_upstream_of_or_within ISO MGI:3051640 (MGI:5779244|PMID:26828067) RGD PMID:26828067 MGI:5779244 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 involved_in ISO (PMID:19790068) RGD PMID:19790068 NCBI chr12:41,938,533...41,977,517
Ensembl chr12:41,938,560...41,977,517 		JBrowse link
positive regulation of prostaglandin secretion involved in immune response term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mif macrophage migration inhibitory factor involved_in ISO (MGI:2156302|PMID:11756671) RGD PMID:11756671 MGI:2156302 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504 		JBrowse link
prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc4 ATP binding cassette subfamily C member 4 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:25173977)
GO_REF:0000107		 RGD
Ensembl		 PMID:25173977 GO_REF:0000107 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Lep leptin involved_in ISS
ISO		 GO_REF:0000024
(PMID:19688109)		 UniProt
RGD		 PMID:19688109 GO_REF:0000024 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Nos2 nitric oxide synthase 2 involved_in ISO
IEA
ISS		 (PMID:19688109)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:19688109 GO_REF:0000024 GO_REF:0000107 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of ISO MGI:2386080 (MGI:3616954|PMID:16269410) RGD PMID:16269410 MGI:3616954 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 acts_upstream_of_or_within ISO (MGI:6501918|PMID:32484881) RGD PMID:32484881 MGI:6501918 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
regulation of arachidonic acid secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syk spleen associated tyrosine kinase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:87668|PMID:9171347)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:9171347 GO_REF:0000024 GO_REF:0000107 MGI:87668 NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410 		JBrowse link
regulation of prostaglandin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:18703674) RGD PMID:18703674 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    localization 5601
      establishment of localization 4940
        transport 4764
          secretion 1184
            icosanoid secretion 55
              arachidonic acid secretion + 36
              negative regulation of icosanoid secretion + 5
              positive regulation of icosanoid secretion + 22
              prostaglandin secretion + 23
              regulation of icosanoid secretion + 28
Path 2
Term Annotations click to browse term
  biological_process 19818
    localization 5601
      establishment of localization 4940
        transport 4764
          organic substance transport 2929
            organic anion transport 480
              carboxylic acid transport 392
                icosanoid transport 70
                  icosanoid secretion 55
                    arachidonic acid secretion + 36
                    negative regulation of icosanoid secretion + 5
                    positive regulation of icosanoid secretion + 22
                    prostaglandin secretion + 23
                    regulation of icosanoid secretion + 28
paths to the root