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ONTOLOGY REPORT - ANNOTATIONS

Term:AMPA glutamate receptor complex
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Accession:GO:0032281 term browser browse the term
Definition:An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
Synonyms:exact_synonym: AMPA-selective glutamate receptor complex;   alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
 related_synonym: AMPA receptor


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AMPA glutamate receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12, lysophospholipase part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr 3:139,659,315...139,719,529
Ensembl chr 3:139,659,317...139,719,564 		JBrowse link
G Abhd6 abhydrolase domain containing 6, acylglycerol lipase part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr15:16,859,740...16,907,094
Ensembl chr15:16,859,738...16,906,985 		JBrowse link
G Cacng2 calcium voltage-gated channel auxiliary subunit gamma 2 part_of IDA
IBA
ISO		 PMID:19265014
GO_REF:0000033
(PMID:22632720)		 GO_Central
RGD		 PMID:22632720 PMID:19265014 GO_REF:0000033, RGD:8554136 NCBI chr 7:109,572,838...109,698,516
Ensembl chr 7:109,574,459...109,697,227 		JBrowse link
G Cacng3 calcium voltage-gated channel auxiliary subunit gamma 3 part_of IDA
IBA
ISO		 PMID:19265014
GO_REF:0000033
(PMID:22632720)		 GO_Central
RGD		 PMID:22632720 PMID:19265014 GO_REF:0000033, RGD:8554136 NCBI chr 1:177,201,361...177,297,019
Ensembl chr 1:177,201,288...177,297,024 		JBrowse link
G Cacng4 calcium voltage-gated channel auxiliary subunit gamma 4 part_of IDA
IBA
ISO		 PMID:19265014
GO_REF:0000033
(PMID:22632720)		 GO_Central
RGD		 PMID:22632720 PMID:19265014 GO_REF:0000033, RGD:8554136 NCBI chr10:92,683,778...92,745,842
Ensembl chr10:92,683,761...92,746,126 		JBrowse link
G Cacng5 calcium voltage-gated channel auxiliary subunit gamma 5 part_of IDA
IBA		 PMID:19265014
GO_REF:0000033		 GO_Central PMID:19265014 GO_REF:0000033, RGD:8554136 NCBI chr10:92,827,441...92,869,632
Ensembl chr10:92,829,196...92,869,614 		JBrowse link
G Cacng7 calcium voltage-gated channel auxiliary subunit gamma 7 part_of IDA
IBA		 PMID:19265014
GO_REF:0000033		 GO_Central PMID:19265014 GO_REF:0000033, RGD:8554136 NCBI chr 1:65,800,059...65,831,246
Ensembl chr 1:65,800,355...65,831,006 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 part_of IDA
IEA
IBA		 PMID:19265014
GO_REF:0000117
GO_REF:0000033		 UniProt
GO_Central		 PMID:19265014 GO_REF:0000033 GO_REF:0000117, RGD:8554136 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089 		JBrowse link
G Cnih2 cornichon family AMPA receptor auxiliary protein 2 part_of IDA PMID:19265014 MGI PMID:19265014 RGD:8554136 NCBI chr 1:202,399,416...202,405,110
Ensembl chr 1:202,399,419...202,405,089 		JBrowse link
G Cnih3 cornichon family AMPA receptor auxiliary protein 3 part_of IDA PMID:19265014 UniProt PMID:19265014 RGD:8554136 NCBI chr13:93,016,707...93,208,168
Ensembl chr13:93,099,784...93,208,121 		JBrowse link
G Cpt1c carnitine palmitoyltransferase 1c part_of IEA
ISO		 GO_REF:0000107
(PMID:22632720)		 Ensembl
RGD		 PMID:22632720 GO_REF:0000107 NCBI chr 1:95,442,814...95,457,347
Ensembl chr 1:95,442,817...95,457,342 		JBrowse link
G Dlg3 discs large MAGUK scaffold protein 3 part_of IEA
ISO		 GO_REF:0000107
(PMID:22632720)		 Ensembl
RGD		 PMID:22632720 GO_REF:0000107 NCBI chr  X:65,859,653...65,911,887
Ensembl chr  X:65,860,172...65,910,322 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 part_of ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:15883194), (PMID:22632720)		 BHF-UCL
Ensembl
RGD		 PMID:15883194 PMID:22632720 GO_REF:0000024 GO_REF:0000107 NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 part_of IEA
IDA
IBA
ISO		 GO_REF:0000107
PMID:19265014
GO_REF:0000118
GO_REF:0000033
(PMID:23739980)
(MGI:59246|PMID:1699805), (PMID:15883194), (PMID:22632720)		 Ensembl
TreeGrafter
GO_Central
RGD		 PMID:1699805 PMID:15883194 PMID:22632720 PMID:23739980 PMID:19265014 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:59246, RGD:8554136 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 part_of IDA
IEA
IBA
ISO		 PMID:19946266
PMID:19265014
GO_REF:0000118
GO_REF:0000033
(PMID:15883194), (PMID:22632720)		 TreeGrafter
GO_Central
RGD		 PMID:15883194 PMID:22632720 PMID:19946266 PMID:19265014 GO_REF:0000033 GO_REF:0000118, RGD:8553832, RGD:8554136 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 part_of IDA
IEA
IBA
ISO		 PMID:19265014
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118
(PMID:22632720)		 Ensembl
GO_Central
TreeGrafter
RGD		 PMID:22632720 PMID:19265014 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:8554136 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gria4 glutamate ionotropic receptor AMPA type subunit 4 part_of IDA
IEA
IBA
ISO		 PMID:19265014
GO_REF:0000118
GO_REF:0000033
(PMID:15883194), (PMID:22632720)		 TreeGrafter
GO_Central
RGD		 PMID:15883194 PMID:22632720 PMID:19265014 GO_REF:0000033 GO_REF:0000118, RGD:8554136 NCBI chr 8:1,562,118...2,035,035
Ensembl chr 8:1,562,119...2,034,979 		JBrowse link
G Lrrtm4 leucine rich repeat transmembrane neuronal 4 part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr 4:112,545,874...113,338,713
Ensembl chr 4:112,545,917...113,335,865 		JBrowse link
G Nrn1 neuritin 1 part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr17:28,129,969...28,138,898
Ensembl chr17:28,129,977...28,138,896 		JBrowse link
G Olfm1 olfactomedin 1 part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239 		JBrowse link
G Olfm2 olfactomedin 2 part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr 8:19,204,472...19,282,154
Ensembl chr 8:19,204,475...19,282,117 		JBrowse link
G Olfm3 olfactomedin 3 part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr 2:202,729,610...202,952,120
Ensembl chr 2:202,729,936...202,952,112 		JBrowse link
G Porcn porcupine O-acyltransferase part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr  X:14,285,864...14,298,481
Ensembl chr  X:14,285,871...14,298,481 		JBrowse link
G Sacm1l SAC1 like phosphatidylinositide phosphatase part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr 8:123,176,017...123,232,413
Ensembl chr 8:123,172,536...123,232,413 		JBrowse link
G Shisa6 shisa family member 6 part_of IBA
ISO		 GO_REF:0000033
(PMID:22632720)		 GO_Central
RGD		 PMID:22632720 GO_REF:0000033 NCBI chr10:50,897,740...51,192,111
Ensembl chr10:50,903,333...51,192,063 		JBrowse link
G Shisa7 shisa family member 7 NOT|part_of ISO
IBA		 (MGI:6377643|PMID:31601770)
GO_REF:0000033		 RGD
GO_Central		 PMID:31601770 GO_REF:0000033 MGI:6377643 NCBI chr 1:68,993,900...69,012,943
Ensembl chr 1:68,994,025...69,012,943 		JBrowse link
G Shisa8 shisa family member 8 part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 7:113,722,408...113,727,858
Ensembl chr 7:113,722,408...113,727,858 		JBrowse link
G Shisa9 shisa family member 9 part_of ISO (PMID:22632720) RGD PMID:22632720 NCBI chr10:3,335,616...3,629,334
Ensembl chr10:3,337,979...3,627,773 		JBrowse link
G Vwc2 von Willebrand factor C domain containing 2 part_of IBA
ISO		 GO_REF:0000033
(PMID:22632720)		 GO_Central
RGD		 PMID:22632720 GO_REF:0000033 NCBI chr14:85,683,670...85,825,068
Ensembl chr14:85,684,414...85,818,524 		JBrowse link
G Vwc2l von Willebrand factor C domain containing 2 like part_of IBA
ISO		 GO_REF:0000033
(PMID:22632720)		 GO_Central
RGD		 PMID:22632720 GO_REF:0000033 NCBI chr 9:72,252,793...72,448,543
Ensembl chr 9:72,253,387...72,444,839 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 21254
    protein-containing complex 6911
      receptor complex 456
        plasma membrane signaling receptor complex 224
          neurotransmitter receptor complex 47
            ionotropic glutamate receptor complex 45
              AMPA glutamate receptor complex 30
Path 2
Term Annotations click to browse term
  cellular_component 21254
    cellular anatomical entity 21098
      membrane 10447
        membrane protein complex 1445
          plasma membrane protein complex 652
            plasma membrane signaling receptor complex 224
              neurotransmitter receptor complex 47
                ionotropic glutamate receptor complex 45
                  AMPA glutamate receptor complex 30
paths to the root