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ONTOLOGY REPORT - ANNOTATIONS


Term:AMPA glutamate receptor complex
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Accession:GO:0032281 term browser browse the term
Definition:An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
Synonyms:exact_synonym: AMPA-selective glutamate receptor complex;   alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
 related_synonym: AMPA receptor



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AMPA glutamate receptor complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABHD12 abhydrolase domain containing 12, lysophospholipase part_of IEA Ensembl GO_REF:0000107 NCBI chr20:25,239,710...25,335,941
Ensembl chr20:25,645,046...25,740,943
JBrowse link
G ABHD6 abhydrolase domain containing 6, acylglycerol lipase part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:58,172,334...58,227,531
Ensembl chr 3:59,586,573...59,641,824
JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr22:17,475,693...17,618,299
Ensembl chr22:35,317,121...35,454,850
JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 Ensembl chr16:24,501,881...24,608,921 JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr17:60,900,645...60,969,659 JBrowse link
G CACNG5 calcium voltage-gated channel auxiliary subunit gamma 5 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr17:60,771,501...60,831,190
Ensembl chr17:65,979,469...66,031,723
JBrowse link
G CACNG7 calcium voltage-gated channel auxiliary subunit gamma 7 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr19:50,849,785...50,880,904
Ensembl chr19:59,701,451...59,724,809
JBrowse link
G CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 part_of ISO PMID:19265014 UniProt PMID:19265014 RGD:8554136 NCBI chr19:50,899,256...50,920,028 JBrowse link
G CNIH2 cornichon family AMPA receptor auxiliary protein 2 part_of ISO PMID:19265014 MGI PMID:19265014 RGD:8554136 NCBI chr11:61,643,633...61,649,646
Ensembl chr11:64,969,447...64,975,156
JBrowse link
G CNIH3 cornichon family AMPA receptor auxiliary protein 3 part_of ISO PMID:19265014 MGI PMID:19265014 RGD:8554136 NCBI chr 1:199,903,319...200,243,433
Ensembl chr 1:205,092,073...205,216,665
JBrowse link
G CPT1C carnitine palmitoyltransferase 1C part_of IEA Ensembl GO_REF:0000107 NCBI chr19:46,705,711...46,727,996
Ensembl chr19:55,626,831...55,647,394
JBrowse link
G DLG3 discs large MAGUK scaffold protein 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr  X:59,712,755...59,773,372
Ensembl chr  X:69,771,477...69,831,369
JBrowse link
G DLG4 discs large MAGUK scaffold protein 4 part_of IEA Ensembl GO_REF:0000107 NCBI chr17:7,219,911...7,247,509
Ensembl chr17:7,207,483...7,235,985
JBrowse link
G GRIA1 glutamate ionotropic receptor AMPA type subunit 1 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 5:148,879,996...149,206,914
Ensembl chr 5:154,879,080...155,204,660
JBrowse link
G GRIA2 glutamate ionotropic receptor AMPA type subunit 2 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 4:149,566,563...149,712,135
Ensembl chr 4:161,380,933...161,524,376
JBrowse link
G GRIA3 glutamate ionotropic receptor AMPA type subunit 3 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr  X:112,380,229...112,687,740
Ensembl chr  X:122,562,330...122,870,130
JBrowse link
G GRIA4 glutamate ionotropic receptor AMPA type subunit 4 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr11:100,498,632...100,873,764
Ensembl chr11:103,983,862...104,355,280
JBrowse link
G LRRTM4 leucine rich repeat transmembrane neuronal 4 part_of ISO (PMID:22632720) MGI PMID:22632720 NCBI chr2A:76,830,224...77,616,298
Ensembl chr2A:79,123,161...79,183,506
JBrowse link
G NRN1 neuritin 1 part_of ISO (PMID:22632720) MGI PMID:22632720 NCBI chr 6:5,832,603...5,841,975
Ensembl chr 6:6,014,000...6,022,870
JBrowse link
G OLFM1 olfactomedin 1 part_of ISO (PMID:22632720) MGI PMID:22632720 NCBI chr 9:106,206,133...106,253,386
Ensembl chr 9:135,205,710...135,252,598
JBrowse link
G OLFM2 olfactomedin 2 part_of ISO (PMID:22632720) MGI PMID:22632720 NCBI chr19:9,408,161...9,488,855
Ensembl chr19:10,071,375...10,151,183
JBrowse link
G OLFM3 olfactomedin 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr 1:104,451,488...104,651,208
Ensembl chr 1:103,168,819...103,364,306
JBrowse link
G PORCN porcupine O-acyltransferase part_of IEA Ensembl GO_REF:0000107 NCBI chr  X:40,807,151...40,819,069
Ensembl chr  X:48,671,829...48,682,980
JBrowse link
G SACM1L SAC1 like phosphatidylinositide phosphatase part_of ISO (PMID:22632720) MGI PMID:22632720 NCBI chr 3:45,596,775...45,652,482
Ensembl chr 3:46,704,565...46,760,104
JBrowse link
G SHISA6 shisa family member 6 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr17:40,081,234...40,405,916
Ensembl chr17:44,836,825...45,154,241
JBrowse link
G SHISA7 shisa family member 7 NOT|part_of ISO (MGI:6377643|PMID:31601770) UniProt PMID:31601770 MGI:6377643 NCBI chr19:52,475,852...52,496,819 JBrowse link
G SHISA9 shisa family member 9 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr16:11,833,062...12,494,972
Ensembl chr16:13,258,945...13,591,356
JBrowse link
G VWC2 von Willebrand factor C domain containing 2 part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr 7:50,412,363...50,562,837
Ensembl chr 7:50,661,384...50,800,814
JBrowse link
G VWC2L von Willebrand factor C domain containing 2 like part_of IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 NCBI chr2B:101,666,338...101,835,393
Ensembl chr2B:220,143,121...220,330,678
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17179
    protein-containing complex 5910
      receptor complex 403
        plasma membrane signaling receptor complex 191
          neurotransmitter receptor complex 49
            ionotropic glutamate receptor complex 44
              AMPA glutamate receptor complex 29
Path 2
Term Annotations click to browse term
  cellular_component 17179
    cellular anatomical entity 16965
      membrane 8101
        membrane protein complex 1248
          plasma membrane protein complex 578
            plasma membrane signaling receptor complex 191
              neurotransmitter receptor complex 49
                ionotropic glutamate receptor complex 44
                  AMPA glutamate receptor complex 29
paths to the root