ONTOLOGY REPORT - ANNOTATIONS |
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Term: | regulation of protein polymerization |
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Accession: | GO:0032271
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browse the term
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Definition: | Any process that modulates the frequency, rate or extent of the process of creating protein polymers. |
Synonyms: | exact_synonym: | regulation of protein polymerisation |
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GViewer not supported for the selected species.
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Gsn |
gelsolin |
involved_in |
ISO |
(PMID:19666531) (MGI:5619440|PMID:23325791) |
UniProt |
PMID:19666531 PMID:23325791 |
MGI:5619440 |
NCBI chrNW_004955419:6,682,202...6,733,361
Ensembl chrNW_004955419:6,682,058...6,733,361
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Myh9 |
myosin heavy chain 9 |
NOT|involved_in |
ISO |
(MGI:5619440|PMID:23325791) |
UniProt |
PMID:23325791 |
MGI:5619440 |
NCBI chrNW_004955413:22,881,759...22,972,182
Ensembl chrNW_004955413:22,881,045...22,972,450
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Scin |
scinderin |
involved_in |
ISO |
(PMID:19666531) |
UniProt |
PMID:19666531 |
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NCBI chrNW_004955410:16,286,131...16,358,286
Ensembl chrNW_004955410:16,285,217...16,358,280
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Tpm1 |
tropomyosin 1 |
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ISO |
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RGD |
PMID:15779917 |
RGD:1600523 |
NCBI chrNW_004955450:12,197,241...12,223,372
Ensembl chrNW_004955450:12,194,755...12,224,011
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Vil1 |
villin 1 |
involved_in |
ISO |
(PMID:16921170), (PMID:17182858), (PMID:19808673) |
UniProt |
PMID:16921170 PMID:17182858 PMID:19808673 |
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NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011
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Add1 |
adducin 1 |
involved_in |
ISO |
(PMID:8626479) |
BHF-UCL |
PMID:8626479 |
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NCBI chrNW_004955514:1,784,302...1,812,845
Ensembl chrNW_004955514:1,783,814...1,815,917
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Add2 |
adducin 2 |
involved_in |
ISO |
(PMID:8626479) |
BHF-UCL |
PMID:8626479 |
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NCBI chrNW_004955424:14,411,279...14,517,813
Ensembl chrNW_004955424:14,411,124...14,517,813
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G |
Capza1 |
capping actin protein of muscle Z-line subunit alpha 1 |
acts_upstream_of_or_within |
ISO |
(PMID:17656356) |
MGI |
PMID:17656356 |
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NCBI chrNW_004955435:16,048,213...16,087,814
Ensembl chrNW_004955435:16,048,213...16,087,814
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Dbnl |
drebrin like |
NOT|acts_upstream_of_or_within |
ISO |
(PMID:10637315) |
MGI |
PMID:10637315 |
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NCBI chrNW_004955456:7,912,827...7,924,373
Ensembl chrNW_004955456:7,912,827...7,924,787
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Eps8 |
EGFR pathway substrate 8, signaling adaptor |
involved_in |
ISO |
(MGI:4460022|PMID:20532239), (MGI:5486559|PMID:15558031) (MGI:5476881|PMID:23314863) |
UniProt |
PMID:15558031 PMID:20532239 PMID:23314863 |
MGI:4460022 MGI:5476881 MGI:5486559 |
NCBI chrNW_004955413:12,267,701...12,386,088
Ensembl chrNW_004955413:12,266,371...12,386,088
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Rdx |
radixin |
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ISO |
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RGD |
PMID:2500445 |
RGD:8693627 |
NCBI chrNW_004955412:12,100,436...12,184,444
Ensembl chrNW_004955412:12,100,359...12,172,545
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G |
Twf1 |
twinfilin actin binding protein 1 |
involved_in |
ISO |
(MGI:3840765|PMID:18837697) |
BHF-UCL |
PMID:18837697 |
MGI:3840765 |
NCBI chrNW_004955500:3,050,028...3,070,799
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Twf2 |
twinfilin actin binding protein 2 |
involved_in |
ISO |
(MGI:3840765|PMID:18837697) |
BHF-UCL |
PMID:18837697 |
MGI:3840765 |
NCBI chrNW_004955532:3,835,620...3,844,760
Ensembl chrNW_004955532:3,834,579...3,844,760
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Vil1 |
villin 1 |
involved_in |
ISO |
(PMID:15272027) |
UniProt |
PMID:15272027 |
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NCBI chrNW_004955453:14,935,450...14,961,011
Ensembl chrNW_004955453:14,935,456...14,961,011
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Add1 |
adducin 1 |
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ISO |
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RGD |
PMID:8675693 |
RGD:7174724 |
NCBI chrNW_004955514:1,784,302...1,812,845
Ensembl chrNW_004955514:1,783,814...1,815,917
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Arfgef1 |
ADP ribosylation factor guanine nucleotide exchange factor 1 |
involved_in |
ISO |
(PMID:22084092) |
UniProt |
PMID:22084092 |
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NCBI chrNW_004955444:11,986,595...12,110,172
Ensembl chrNW_004955444:11,986,595...12,110,172
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Bbs4 |
Bardet-Biedl syndrome 4 |
acts_upstream_of_or_within |
ISO |
(PMID:23716571) |
MGI |
PMID:23716571 |
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NCBI chrNW_004955450:4,624,634...4,668,470
Ensembl chrNW_004955450:4,631,266...4,662,719
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Capn1 |
calpain 1 |
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ISO |
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RGD |
PMID:25653381 |
RGD:13792590 |
NCBI chrNW_004955422:20,006,448...20,026,984
Ensembl chrNW_004955422:20,004,426...20,025,708
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Cyrib |
CYFIP related Rac1 interactor B |
involved_in |
ISO |
(PMID:30250061) |
UniProt |
PMID:30250061 |
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NCBI chrNW_004955461:4,634,324...4,786,723
Ensembl chrNW_004955461:4,632,263...4,662,016
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Fhod3 |
formin homology 2 domain containing 3 |
acts_upstream_of_or_within |
ISO |
(PMID:19706596) |
MGI |
PMID:19706596 |
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NCBI chrNW_004955402:22,822,060...23,277,993
Ensembl chrNW_004955402:22,821,710...23,279,222
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Hip1r |
huntingtin interacting protein 1 related |
involved_in |
ISO |
(PMID:17318189) (MGI:5805366|PMID:17318189) |
ParkinsonsUK-UCL |
PMID:17318189 |
MGI:5805366 |
NCBI chrNW_004955482:5,885,807...5,896,386
Ensembl chrNW_004955482:5,884,839...5,896,389
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Kank1 |
KN motif and ankyrin repeat domains 1 |
involved_in acts_upstream_of_or_within |
ISO |
(PMID:18458160) (PMID:17996375) |
UniProt MGI |
PMID:17996375 PMID:18458160 |
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NCBI chrNW_004955434:5,247,278...5,279,043
Ensembl chrNW_004955434:5,191,846...5,279,739
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Mkks |
MKKS centrosomal shuttling protein |
acts_upstream_of_or_within |
ISO |
(PMID:23716571) |
MGI |
PMID:23716571 |
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NCBI chrNW_004955415:20,292,311...20,315,850
Ensembl chrNW_004955415:20,292,663...20,300,797
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Myadm |
myeloid associated differentiation marker |
involved_in |
ISO |
(PMID:23264465) |
UniProt |
PMID:23264465 |
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NCBI chrNW_004955604:280,977...284,381
Ensembl chrNW_004955604:280,977...284,381
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Pecam1 |
platelet and endothelial cell adhesion molecule 1 |
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ISO |
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RGD |
PMID:17662049 |
RGD:7240703 |
NCBI chrNW_004955478:7,448,584...7,531,860
Ensembl chrNW_004955478:7,478,492...7,531,188
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Pfn1 |
profilin 1 |
involved_in |
ISO |
(PMID:7758455) |
UniProt |
PMID:7758455 |
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NCBI chrNW_004955467:10,357,838...10,360,651
Ensembl chrNW_004955467:10,357,838...10,360,651
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Pfn2 |
profilin 2 |
involved_in |
ISO |
(PMID:7758455) |
UniProt |
PMID:7758455 |
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NCBI chrNW_004955448:1,199,447...1,201,718
Ensembl chrNW_004955448:1,199,688...1,203,400
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Prkcd |
protein kinase C delta |
involved_in |
ISO |
(MGI:3813784|PMID:16940418) |
UniProt |
PMID:16940418 |
MGI:3813784 |
NCBI chrNW_004955430:3,125,066...3,151,857
Ensembl chrNW_004955430:3,124,738...3,153,274
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Slit2 |
slit guidance ligand 2 |
involved_in |
ISO |
(PMID:19759280) |
UniProt |
PMID:19759280 |
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NCBI chrNW_004955480:3,982,977...4,314,160
Ensembl chrNW_004955480:3,984,586...4,313,908
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Tlr2 |
toll like receptor 2 |
involved_in |
ISO |
(MGI:5307186|PMID:22198949) |
ARUK-UCL |
PMID:22198949 |
MGI:5307186 |
NCBI chrNW_004955471:8,011,710...8,019,063
Ensembl chrNW_004955471:8,014,910...8,017,258
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Twf1 |
twinfilin actin binding protein 1 |
involved_in |
ISO |
(MGI:2673741|PMID:12807912) |
BHF-UCL |
PMID:12807912 |
MGI:2673741 |
NCBI chrNW_004955500:3,050,028...3,070,799
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G |
Twf2 |
twinfilin actin binding protein 2 |
involved_in |
ISO |
(MGI:2673741|PMID:12807912) |
BHF-UCL |
PMID:12807912 |
MGI:2673741 |
NCBI chrNW_004955532:3,835,620...3,844,760
Ensembl chrNW_004955532:3,834,579...3,844,760
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G |
Carmil1 |
capping protein regulator and myosin 1 linker 1 |
involved_in |
ISO |
(MGI:3588909|PMID:16054028) |
UniProt |
PMID:16054028 |
MGI:3588909 |
NCBI chrNW_004955483:1,463,856...1,770,798
Ensembl chrNW_004955483:1,463,805...1,770,520
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Carmil2 |
capping protein regulator and myosin 1 linker 2 |
involved_in |
ISO |
(PMID:26466680) |
UniProt |
PMID:26466680 |
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NCBI chrNW_004955484:9,025,409...9,037,942
Ensembl chrNW_004955484:9,025,460...9,037,580
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Cracd |
capping protein inhibiting regulator of actin dynamics |
involved_in |
ISO |
(PMID:30361697) |
UniProt |
PMID:30361697 |
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NCBI chrNW_004955447:14,650,035...14,672,593
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G |
Washc2c |
WASH complex subunit 2C |
involved_in |
ISO |
(PMID:20498093) |
UniProt |
PMID:20498093 |
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NCBI chrNW_004955546:2,718,758...2,764,277
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G |
Arhgef7 |
Rho guanine nucleotide exchange factor 7 |
involved_in |
ISO |
(PMID:27012601) |
UniProt |
PMID:27012601 |
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NCBI chrNW_004955404:1,749,051...1,835,455
Ensembl chrNW_004955404:1,748,665...1,814,575
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G |
Cdh5 |
cadherin 5 |
involved_in |
ISO |
(PMID:23159740) |
ARUK-UCL |
PMID:23159740 |
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NCBI chrNW_004955433:22,957,718...22,994,515
Ensembl chrNW_004955433:22,967,960...22,992,924
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Clip3 |
CAP-Gly domain containing linker protein 3 |
involved_in |
ISO |
(PMID:15262990) |
UniProt |
PMID:15262990 |
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NCBI chrNW_004955468:2,560,953...2,575,073
Ensembl chrNW_004955468:2,560,953...2,575,291
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G |
Dyrk1a |
dual specificity tyrosine phosphorylation regulated kinase 1A |
involved_in |
ISO |
(MGI:3768476|PMID:17906291) |
ARUK-UCL |
PMID:17906291 |
MGI:3768476 |
NCBI chrNW_004955407:36,456,628...36,588,940
Ensembl chrNW_004955407:36,453,098...36,589,382
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Eml2 |
EMAP like 2 |
involved_in |
ISO |
(PMID:11694528) |
UniProt |
PMID:11694528 |
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NCBI chrNW_004955574:106,788...135,289
Ensembl chrNW_004955574:106,253...135,289
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Fkbp4 |
FKBP prolyl isomerase 4 |
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ISO |
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RGD |
PMID:17435176 |
RGD:5508373 |
NCBI chrNW_004955429:18,334,939...18,344,530
Ensembl chrNW_004955429:18,334,939...18,344,530
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Inpp5j |
inositol polyphosphate-5-phosphatase J |
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ISO |
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RGD |
PMID:16280363 |
RGD:2312436 |
NCBI chrNW_004955455:5,304,346...5,314,432
Ensembl chrNW_004955455:5,304,349...5,316,201
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Map2 |
microtubule associated protein 2 |
involved_in |
ISO |
PMID:28426968 |
ARUK-UCL |
PMID:28426968 |
RGD:13514087 |
NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024
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Mapre1 |
microtubule associated protein RP/EB family member 1 |
involved_in |
ISO |
(PMID:11943150) |
UniProt |
PMID:11943150 |
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NCBI chrNW_004955422:28,346,495...28,358,513
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Sgk1 |
serum/glucocorticoid regulated kinase 1 |
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ISO |
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RGD |
PMID:16982696 |
RGD:1642763 |
NCBI chrNW_004955439:2,399,992...2,406,587
Ensembl chrNW_004955439:2,290,035...2,406,587
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Snca |
synuclein alpha |
involved_in |
ISO |
(PMID:21127069) |
BHF-UCL |
PMID:21127069 |
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NCBI chrNW_004955405:854,011...962,741
Ensembl chrNW_004955405:853,946...965,403
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Stmn1 |
stathmin 1 |
involved_in acts_upstream_of_or_within |
ISO |
(PMID:25198505) (PMID:15652749) |
CAFA MGI |
PMID:15652749 PMID:25198505 |
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NCBI chrNW_004955452:5,387,696...5,393,337
Ensembl chrNW_004955452:5,388,150...5,391,518
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Stmn2 |
stathmin 2 |
involved_in |
ISO |
(PMID:18452648), (PMID:21215777) |
UniProt |
PMID:18452648 PMID:21215777 |
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NCBI chrNW_004955444:1,585,042...1,646,812
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Tbcd |
tubulin folding cofactor D |
involved_in |
ISO |
(PMID:10831612), (PMID:20740604) |
UniProt |
PMID:10831612 PMID:20740604 |
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NCBI chrNW_004955506:273,769...434,205
Ensembl chrNW_004955506:273,954...434,973
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Tubb4a |
tubulin beta 4A class IVa |
involved_in |
ISO |
(PMID:10211825) |
CAFA |
PMID:10211825 |
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NCBI chrNW_004955495:3,134,181...3,138,725
Ensembl chrNW_004955495:3,133,429...3,139,552
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Vdac2 |
voltage dependent anion channel 2 |
involved_in |
ISO |
(MGI:5315363|PMID:12881569) |
UniProt |
PMID:12881569 |
MGI:5315363 |
NCBI chrNW_004955437:16,857,715...16,871,717
Ensembl chrNW_004955437:16,853,433...16,872,345
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Actr3 |
actin related protein 3 |
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ISO |
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RGD |
PMID:18256280 |
RGD:2306202 |
NCBI chrNW_004955459:15,216,914...15,284,013
Ensembl chrNW_004955459:15,216,914...15,284,013
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Alox15 |
arachidonate 15-lipoxygenase |
involved_in |
ISO |
(MGI:5508294|PMID:11278875) |
UniProt |
PMID:11278875 |
MGI:5508294 |
NCBI chrNW_004955467:10,032,792...10,039,789
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Arf6 |
ADP ribosylation factor 6 |
involved_in |
ISO |
(PMID:10036235) |
UniProt |
PMID:10036235 |
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NCBI chrNW_004955409:12,814,814...12,818,142
Ensembl chrNW_004955409:12,817,496...12,818,023
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Arpc2 |
actin related protein 2/3 complex subunit 2 |
acts_upstream_of_or_within |
ISO |
(PMID:18836449) |
MGI |
PMID:18836449 |
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NCBI chrNW_004955453:15,117,978...15,145,895
Ensembl chrNW_004955453:15,116,093...15,146,041
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Bag4 |
BAG cochaperone 4 |
involved_in |
ISO |
(MGI:5292318|PMID:21712384) |
UniProt |
PMID:21712384 |
MGI:5292318 |
NCBI chrNW_004955463:13,788,852...13,824,135
Ensembl chrNW_004955463:13,788,852...13,824,135
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Baiap2l1 |
BAR/IMD domain containing adaptor protein 2 like 1 |
involved_in |
ISO |
(PMID:21098279) |
UniProt |
PMID:21098279 |
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NCBI chrNW_004955460:14,174,592...14,259,416
Ensembl chrNW_004955460:14,176,111...14,258,971
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Bin1 |
bridging integrator 1 |
involved_in |
ISO |
(MGI:5583915|PMID:24836577) |
ARUK-UCL |
PMID:24836577 |
MGI:5583915 |
NCBI chrNW_004955459:3,376,149...3,423,157
Ensembl chrNW_004955459:3,399,611...3,422,621
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Carmil1 |
capping protein regulator and myosin 1 linker 1 |
involved_in |
ISO |
(MGI:3588909|PMID:16054028) |
UniProt |
PMID:16054028 |
MGI:3588909 |
NCBI chrNW_004955483:1,463,856...1,770,798
Ensembl chrNW_004955483:1,463,805...1,770,520
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Ccl21 |
C-C motif chemokine ligand 21 |
involved_in |
ISO |
(PMID:11242036) |
BHF-UCL |
PMID:11242036 |
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NCBI chrNW_004955472:1,427,660...1,428,771
Ensembl chrNW_004955472:1,427,710...1,429,102
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Ccl24 |
C-C motif chemokine ligand 24 |
involved_in |
ISO |
(PMID:19525930) |
BHF-UCL |
PMID:19525930 |
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NCBI chrNW_004955456:14,582,812...14,588,574
Ensembl chrNW_004955456:14,583,610...14,585,169
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Ccl26 |
C-C motif chemokine ligand 26 |
involved_in |
ISO |
(PMID:19525930) |
BHF-UCL |
PMID:19525930 |
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NCBI chrNW_004955456:14,554,583...14,558,967
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Cdc42ep2 |
CDC42 effector protein 2 |
involved_in |
ISO |
(PMID:11035016) |
UniProt |
PMID:11035016 |
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NCBI chrNW_004955422:19,922,179...19,928,570
Ensembl chrNW_004955422:19,922,179...19,928,570
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Cracd |
capping protein inhibiting regulator of actin dynamics |
involved_in |
ISO |
(PMID:30361697) |
UniProt |
PMID:30361697 |
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NCBI chrNW_004955447:14,650,035...14,672,593
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Csf3 |
colony stimulating factor 3 |
involved_in |
ISO |
(PMID:23001182) |
BHF-UCL |
PMID:23001182 |
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NCBI chrNW_004955451:14,688,181...14,690,126
Ensembl chrNW_004955451:14,688,181...14,690,126
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Cttn |
cortactin |
involved_in |
ISO |
(PMID:24700464) PMID:18768925 |
UniProt |
PMID:18768925 PMID:24700464 |
RGD:10047281 |
NCBI chrNW_004955422:15,838,036...15,874,067
Ensembl chrNW_004955422:15,835,145...15,874,108
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Dlg1 |
discs large MAGUK scaffold protein 1 |
acts_upstream_of_or_within |
ISO |
(PMID:15699074) |
MGI |
PMID:15699074 |
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NCBI chrNW_004955420:13,068,289...13,273,805
Ensembl chrNW_004955420:13,068,289...13,273,805
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Evl |
Enah/Vasp-like |
involved_in |
ISO |
(MGI:5545940|PMID:23153535) |
UniProt |
PMID:23153535 |
MGI:5545940 |
NCBI chrNW_004955438:21,198,761...21,298,657
Ensembl chrNW_004955438:21,198,763...21,298,657
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Fchsd1 |
FCH and double SH3 domains 1 |
involved_in |
ISO |
(MGI:6233193|PMID:23437151) |
UniProt |
PMID:23437151 |
MGI:6233193 |
NCBI chrNW_004955415:12,123,520...12,135,412
Ensembl chrNW_004955415:12,123,520...12,135,412
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G |
Fchsd2 |
FCH and double SH3 domains 2 |
involved_in |
ISO |
(MGI:6233193|PMID:23437151) |
UniProt |
PMID:23437151 |
MGI:6233193 |
NCBI chrNW_004955414:18,343,832...18,597,675
Ensembl chrNW_004955414:18,343,832...18,597,675
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Fer |
FER tyrosine kinase |
involved_in |
ISO |
(PMID:19738202) |
UniProt |
PMID:19738202 |
|
NCBI chrNW_004955418:5,612,919...5,981,549
Ensembl chrNW_004955418:5,614,950...5,981,636
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Fmn1 |
formin 1 |
acts_upstream_of_or_within |
ISO |
(PMID:14647292) |
MGI |
PMID:14647292 |
|
NCBI chrNW_004955416:1,365,797...1,774,025
Ensembl chrNW_004955416:1,365,765...1,774,027
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Grb2 |
growth factor receptor bound protein 2 |
acts_upstream_of_or_within |
ISO |
(PMID:17923684) |
MGI |
PMID:17923684 |
|
NCBI chrNW_004955553:2,186,590...2,258,964
Ensembl chrNW_004955553:2,186,590...2,259,456
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Icam1 |
intercellular adhesion molecule 1 |
|
ISO |
|
RGD |
PMID:17662049 |
RGD:7240703 |
NCBI chrNW_004955495:1,561,464...1,573,282
Ensembl chrNW_004955495:1,561,714...1,574,755
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Kirrel1 |
kirre like nephrin family adhesion molecule 1 |
acts_upstream_of_or_within |
ISO |
(PMID:17923684) |
MGI |
PMID:17923684 |
|
NCBI chrNW_004955468:9,820,649...9,919,958
Ensembl chrNW_004955468:9,821,303...9,916,667
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Lmod1 |
leiomodin 1 |
involved_in |
ISO |
(PMID:26370058) |
UniProt |
PMID:26370058 |
|
NCBI chrNW_004955406:37,967,098...38,012,908
Ensembl chrNW_004955406:37,964,643...38,013,405
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Lmod2 |
leiomodin 2 |
involved_in |
ISO |
(PMID:26370058) |
UniProt |
PMID:26370058 |
|
NCBI chrNW_004955479:5,143,430...5,151,096
Ensembl chrNW_004955479:5,142,609...5,150,656
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G |
Map3k1 |
mitogen-activated protein kinase kinase kinase 1 |
acts_upstream_of_or_within |
ISO |
(PMID:12941696), (PMID:25224220) |
MGI |
PMID:12941696 PMID:25224220 |
|
NCBI chrNW_004955446:11,022,091...11,090,136
Ensembl chrNW_004955446:11,021,971...11,090,136
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Mlst8 |
MTOR associated protein, LST8 homolog |
acts_upstream_of_or_within |
ISO |
(PMID:15467718) |
MGI |
PMID:15467718 |
|
NCBI chrNW_004955442:15,056,363...15,060,300
Ensembl chrNW_004955442:15,056,363...15,060,300
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Mtor |
mechanistic target of rapamycin kinase |
acts_upstream_of_or_within |
ISO |
(PMID:15467718) |
MGI |
PMID:15467718 |
|
NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694
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Myo1c |
myosin IC |
|
ISO |
|
RGD |
PMID:22918957 |
RGD:11073622 |
NCBI chrNW_004955481:1,676,788...1,701,421
Ensembl chrNW_004955481:1,676,728...1,703,488
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G |
Nck1 |
NCK adaptor protein 1 |
involved_in acts_upstream_of_or_within |
ISO |
(PMID:12110186) (PMID:17923684) |
UniProt MGI |
PMID:12110186 PMID:17923684 |
|
NCBI chrNW_004955501:1,867,956...1,963,091
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Nck2 |
NCK adaptor protein 2 |
involved_in |
ISO |
(PMID:12110186) |
UniProt |
PMID:12110186 |
|
NCBI chrNW_004955470:10,487,962...10,593,046
Ensembl chrNW_004955470:10,487,481...10,593,046
|
|
G |
Nckap1 |
NCK associated protein 1 |
involved_in |
ISO |
(MGI:5897521|PMID:27927633) |
BHF-UCL |
PMID:27927633 |
MGI:5897521 |
NCBI chrNW_004955403:14,476,689...14,554,380
Ensembl chrNW_004955403:14,480,162...14,554,702
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G |
Nckap1l |
NCK associated protein 1 like |
involved_in |
ISO |
(MGI:3818191|PMID:19015308) (PMID:16417406), (PMID:32647003) |
UniProt |
PMID:16417406 PMID:19015308 PMID:32647003 |
MGI:3818191 |
NCBI chrNW_004955458:1,733,799...1,785,591
Ensembl chrNW_004955458:1,733,883...1,784,182
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G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
acts_upstream_of_or_within |
ISO |
(PMID:17923684) |
MGI |
PMID:17923684 |
|
NCBI chrNW_004955468:2,715,728...2,734,174
Ensembl chrNW_004955468:2,714,419...2,734,830
|
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G |
Pfn1 |
profilin 1 |
involved_in |
ISO |
(PMID:23153535) |
UniProt |
PMID:23153535 |
|
NCBI chrNW_004955467:10,357,838...10,360,651
Ensembl chrNW_004955467:10,357,838...10,360,651
|
|
G |
Pfn2 |
profilin 2 |
involved_in acts_upstream_of_or_within |
ISO |
(PMID:23153535) (PMID:17541406) |
UniProt MGI |
PMID:17541406 PMID:23153535 |
|
NCBI chrNW_004955448:1,199,447...1,201,718
Ensembl chrNW_004955448:1,199,688...1,203,400
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G |
Prkce |
protein kinase C epsilon |
involved_in |
ISO |
(MGI:5306325|PMID:11746497) |
UniProt |
PMID:11746497 |
MGI:5306325 |
NCBI chrNW_004955441:12,642,703...13,142,396
Ensembl chrNW_004955441:12,642,697...13,139,372
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|
G |
Ptk2b |
protein tyrosine kinase 2 beta |
involved_in |
ISO |
(PMID:18765415) |
UniProt |
PMID:18765415 |
|
NCBI chrNW_004955403:49,856,056...49,970,800
Ensembl chrNW_004955403:49,855,541...49,973,225
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|
G |
Rac1 |
Rac family small GTPase 1 |
acts_upstream_of_or_within |
ISO |
(PMID:12853475) |
MGI |
PMID:12853475 |
|
NCBI chrNW_004955460:13,270,159...13,295,562
Ensembl chrNW_004955460:13,270,159...13,311,351
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G |
Rhoa |
ras homolog family member A |
|
ISO |
|
RGD |
PMID:17369454 |
RGD:1642965 |
NCBI chrNW_004955532:1,300,821...1,347,453
Ensembl chrNW_004955532:1,300,462...1,347,451
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|
G |
Rictor |
RPTOR independent companion of MTOR complex 2 |
acts_upstream_of_or_within |
ISO |
(PMID:15467718) |
MGI |
PMID:15467718 |
|
NCBI chrNW_004955426:23,468,112...23,582,587
Ensembl chrNW_004955426:23,468,112...23,582,587
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|
G |
Snx9 |
sorting nexin 9 |
involved_in |
ISO |
(MGI:6233193|PMID:23437151) |
UniProt |
PMID:23437151 |
MGI:6233193 |
NCBI chrNW_004955439:4,422,385...4,503,408
Ensembl chrNW_004955439:4,421,297...4,503,393
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G |
Tenm1 |
teneurin transmembrane protein 1 |
involved_in |
ISO |
(MGI:5465054|PMID:22698694) |
UniProt |
PMID:22698694 |
MGI:5465054 |
NCBI chrNW_004955473:9,557,822...10,342,007
Ensembl chrNW_004955473:9,770,364...10,337,379
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|
G |
Vasp |
vasodilator stimulated phosphoprotein |
involved_in |
ISO |
(PMID:23153535) |
UniProt |
PMID:23153535 |
|
NCBI chrNW_004955574:21,569...33,705
Ensembl chrNW_004955574:21,911...34,197
|
|
|
G |
Arpc2 |
actin related protein 2/3 complex subunit 2 |
|
ISO |
|
RGD |
PMID:15252126 |
RGD:2306210 |
NCBI chrNW_004955453:15,117,978...15,145,895
Ensembl chrNW_004955453:15,116,093...15,146,041
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G |
Cfl1 |
cofilin 1 |
|
ISO |
|
RGD |
PMID:23704350 |
RGD:11570555 |
NCBI chrNW_004955422:19,479,181...19,482,571
Ensembl chrNW_004955422:19,479,181...19,482,571
|
|
|
G |
Ambra1 |
autophagy and beclin 1 regulator 1 |
involved_in |
ISO |
(PMID:31123703) |
UniProt |
PMID:31123703 |
|
NCBI chrNW_004955422:1,455,392...1,644,368
Ensembl chrNW_004955422:1,455,380...1,644,452
|
|
|
G |
Ckap5 |
cytoskeleton associated protein 5 |
involved_in |
ISO |
(PMID:26414402) |
CACAO |
PMID:26414402 |
|
NCBI chrNW_004955422:1,266,686...1,354,323
Ensembl chrNW_004955422:1,279,158...1,353,894
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|
G |
Dctn1 |
dynactin subunit 1 |
involved_in |
ISO |
(PMID:23874158) |
UniProt |
PMID:23874158 |
|
NCBI chrNW_004955424:11,362,240...11,413,140
Ensembl chrNW_004955424:11,392,812...11,413,140
|
|
G |
Git1 |
GIT ArfGAP 1 |
involved_in |
ISO |
(PMID:27012601) |
UniProt |
PMID:27012601 |
|
NCBI chrNW_004955481:3,671,728...3,681,279
Ensembl chrNW_004955481:3,670,111...3,685,051
|
|
G |
Mecp2 |
methyl-CpG binding protein 2 |
involved_in |
ISO |
(PMID:25527496) |
CAFA |
PMID:25527496 |
|
NCBI chrNW_004955580:674,014...737,586
Ensembl chrNW_004955580:679,109...735,288
|
|
G |
Pak1 |
p21 (RAC1) activated kinase 1 |
involved_in |
ISO |
(PMID:27012601) |
UniProt |
PMID:27012601 |
|
NCBI chrNW_004955414:14,365,325...14,447,470
Ensembl chrNW_004955414:14,365,157...14,450,611
|
|
G |
Pde4dip |
phosphodiesterase 4D interacting protein |
involved_in |
ISO |
(PMID:29162697) |
UniProt |
PMID:29162697 |
|
NCBI chrNW_004955568:1,321,053...1,546,351
Ensembl chrNW_004955568:1,322,470...1,546,256
|
|
|
G |
Akap9 |
A-kinase anchoring protein 9 |
involved_in |
ISO |
(PMID:29162697) |
UniProt |
PMID:29162697 |
|
NCBI chrNW_004955432:8,933,037...9,090,872
Ensembl chrNW_004955432:8,932,952...9,095,065
|
|
G |
Ankrd53 |
ankyrin repeat domain 53 |
involved_in |
ISO |
(PMID:26820536) |
UniProt |
PMID:26820536 |
|
NCBI chrNW_004955424:14,247,070...14,253,072
Ensembl chrNW_004955424:14,247,110...14,252,459
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|
G |
Apc |
APC regulator of WNT signaling pathway |
acts_upstream_of_or_within |
ISO |
(PMID:16525027) |
MGI |
PMID:16525027 |
|
NCBI chrNW_004955418:2,567,804...2,675,062
Ensembl chrNW_004955418:2,566,975...2,674,832
|
|
G |
Arl2 |
ADP ribosylation factor like GTPase 2 |
involved_in |
ISO |
(PMID:10831612), (PMID:20740604) |
UniProt |
PMID:10831612 PMID:20740604 |
|
NCBI chrNW_004955422:20,166,956...20,172,954
Ensembl chrNW_004955422:20,166,956...20,172,950
|
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G |
Cav1 |
caveolin 1 |
|
ISO |
|
RGD |
PMID:16480946 |
RGD:1582162 |
NCBI chrNW_004955432:22,258,262...22,292,403
Ensembl chrNW_004955432:22,258,250...22,292,403
|
|
G |
Cav3 |
caveolin 3 |
|
ISO |
|
RGD |
PMID:16480946 |
RGD:1582162 |
NCBI chrNW_004955561:326,008...335,911
Ensembl chrNW_004955561:325,944...335,914
|
|
G |
Cdk5rap2 |
CDK5 regulatory subunit associated protein 2 |
involved_in |
ISO |
(PMID:29162697) |
UniProt |
PMID:29162697 |
|
NCBI chrNW_004955419:7,412,177...7,606,883
Ensembl chrNW_004955419:7,412,331...7,610,353
|
|
G |
Cdkn1b |
cyclin dependent kinase inhibitor 1B |
acts_upstream_of_or_within |
ISO |
(PMID:15652749) |
MGI |
PMID:15652749 |
|
NCBI chrNW_004955413:9,615,542...9,620,542
Ensembl chrNW_004955413:9,615,542...9,620,542
|
|
G |
Clip1 |
CAP-Gly domain containing linker protein 1 |
involved_in |
ISO |
(PMID:15262990), (PMID:17889670) |
UniProt |
PMID:15262990 PMID:17889670 |
|
NCBI chrNW_004955482:6,213,363...6,330,601
Ensembl chrNW_004955482:6,244,752...6,330,978
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|
G |
Dctn1 |
dynactin subunit 1 |
involved_in |
ISO |
(PMID:23874158) (PMID:16505168) |
UniProt ARUK-UCL |
PMID:16505168 PMID:23874158 |
|
NCBI chrNW_004955424:11,362,240...11,413,140
Ensembl chrNW_004955424:11,392,812...11,413,140
|
|
G |
Drg1 |
developmentally regulated GTP binding protein 1 |
involved_in |
ISO |
(PMID:28855639) |
UniProt |
PMID:28855639 |
|
NCBI chrNW_004955455:5,588,313...5,608,091
Ensembl chrNW_004955455:5,588,313...5,610,964
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Fes |
FES proto-oncogene, tyrosine kinase |
involved_in |
ISO |
(PMID:15485904) |
UniProt |
PMID:15485904 |
|
NCBI chrNW_004955416:14,948,121...14,959,035
Ensembl chrNW_004955416:14,948,123...14,960,005
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|
G |
Gda |
guanine deaminase |
involved_in |
ISO |
PMID:14730308 |
CACAO |
PMID:14730308 |
RGD:10047353 |
NCBI chrNW_004955434:983,388...1,050,413
Ensembl chrNW_004955434:983,388...1,049,948
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G |
Map1b |
microtubule associated protein 1B |
|
ISO |
|
RGD |
PMID:11896150 |
RGD:71122 |
NCBI chrNW_004955575:914,607...1,020,971
Ensembl chrNW_004955575:913,723...1,021,028
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Mapk8 |
mitogen-activated protein kinase 8 |
|
ISO |
|
RGD |
PMID:16618812 |
RGD:1582322 |
NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784
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Mapre1 |
microtubule associated protein RP/EB family member 1 |
involved_in |
ISO |
(PMID:29162697) |
UniProt |
PMID:29162697 |
|
NCBI chrNW_004955422:28,346,495...28,358,513
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Mapt |
microtubule associated protein tau |
involved_in |
ISO |
(PMID:1421571), (PMID:7706316) |
UniProt |
PMID:1421571 PMID:7706316 |
|
NCBI chrNW_004955478:10,222,439...10,271,439
Ensembl chrNW_004955478:10,225,823...10,271,442
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Met |
MET proto-oncogene, receptor tyrosine kinase |
involved_in |
ISO |
(PMID:25198505) |
CAFA |
PMID:25198505 |
|
NCBI chrNW_004955432:22,440,671...22,519,592
Ensembl chrNW_004955432:22,440,637...22,517,647
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|
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Nav3 |
neuron navigator 3 |
involved_in |
ISO |
(PMID:25678558) |
UniProt |
PMID:25678558 |
|
NCBI chrNW_004955405:16,428,643...17,213,253
Ensembl chrNW_004955405:16,869,441...17,213,325
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|
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Numa1 |
nuclear mitotic apparatus protein 1 |
involved_in |
ISO |
(PMID:12445386) |
UniProt |
PMID:12445386 |
|
NCBI chrNW_004955414:19,252,191...19,327,504
Ensembl chrNW_004955414:19,252,191...19,327,504
|
|
G |
Ocln |
occludin |
involved_in |
ISO |
(PMID:20152177) |
ARUK-UCL |
PMID:20152177 |
|
NCBI chrNW_004955575:163,646...210,379
|
|
G |
Pak1 |
p21 (RAC1) activated kinase 1 |
involved_in |
ISO |
(PMID:25198505) |
CAFA |
PMID:25198505 |
|
NCBI chrNW_004955414:14,365,325...14,447,470
Ensembl chrNW_004955414:14,365,157...14,450,611
|
|
G |
Psrc1 |
proline and serine rich coiled-coil 1 |
involved_in |
ISO |
(MGI:3773778|PMID:17310996) |
BHF-UCL |
PMID:17310996 |
MGI:3773778 |
NCBI chrNW_004955435:12,697,179...12,702,021
Ensembl chrNW_004955435:12,697,733...12,700,628
|
|
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Rac1 |
Rac family small GTPase 1 |
involved_in |
ISO |
(PMID:25198505) |
CAFA |
PMID:25198505 |
|
NCBI chrNW_004955460:13,270,159...13,295,562
Ensembl chrNW_004955460:13,270,159...13,311,351
|
|
G |
Rps3 |
ribosomal protein S3 |
involved_in |
ISO |
(PMID:23131551) |
UniProt |
PMID:23131551 |
|
NCBI chrNW_004955414:16,436,899...16,442,325
Ensembl chrNW_004955414:16,436,899...16,443,073
|
|
G |
Slain2 |
SLAIN motif family member 2 |
involved_in |
ISO |
(PMID:21646404) |
UniProt |
PMID:21646404 |
|
NCBI chrNW_004955443:134,631...231,866
Ensembl chrNW_004955443:131,696...231,866
|
|
G |
Togaram1 |
TOG array regulator of axonemal microtubules 1 |
involved_in |
ISO |
(MGI:5796072|PMID:26378256) |
UniProt |
PMID:26378256 |
MGI:5796072 |
NCBI chrNW_004955409:16,885,564...16,967,865
Ensembl chrNW_004955409:16,886,423...16,967,641
|
|
|
G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
involved_in |
ISO |
(PMID:19363271) |
ARUK-UCL |
PMID:19363271 |
|
NCBI chrNW_004955538:1,469,544...1,475,010
Ensembl chrNW_004955538:1,469,544...1,475,019
|
|
G |
Ttbk1 |
tau tubulin kinase 1 |
involved_in |
ISO |
(PMID:16923168) |
ARUK-UCL |
PMID:16923168 |
|
NCBI chrNW_004955437:9,161,880...9,195,098
Ensembl chrNW_004955437:9,165,414...9,197,612
|
|
|
G |
Abitram |
actin binding transcription modulator |
involved_in |
ISO |
(MGI:5632379|PMID:24782708) |
UniProt |
PMID:24782708 |
MGI:5632379 |
NCBI chrNW_004955419:18,029,763...18,034,945
Ensembl chrNW_004955419:18,030,040...18,034,799
|
|
G |
Arhgap18 |
Rho GTPase activating protein 18 |
involved_in |
ISO |
(PMID:21865595) |
UniProt |
PMID:21865595 |
|
NCBI chrNW_004955436:10,470,398...10,642,890
Ensembl chrNW_004955436:10,470,123...10,587,159
|
|
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Coro1a |
coronin 1A |
acts_upstream_of_or_within |
ISO |
(PMID:18836449) |
MGI |
PMID:18836449 |
|
NCBI chrNW_004955493:6,815,148...6,820,295
Ensembl chrNW_004955493:6,811,430...6,826,485
|
|
G |
Daam2 |
dishevelled associated activator of morphogenesis 2 |
involved_in |
ISO |
(PMID:33232676) |
UniProt |
PMID:33232676 |
|
NCBI chrNW_004955437:6,728,703...6,839,903
Ensembl chrNW_004955437:6,728,523...6,839,903
|
|
G |
Dbn1 |
drebrin 1 |
|
ISO |
|
RGD |
PMID:19222710 |
RGD:10395284 |
NCBI chrNW_004955408:29,695,442...29,705,417
Ensembl chrNW_004955408:29,696,266...29,705,416
|
|
G |
Eln |
elastin |
acts_upstream_of_or_within |
ISO |
(PMID:14614988) |
MGI |
PMID:14614988 |
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NCBI chrNW_004955456:13,788,992...13,818,836
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G |
Gba2 |
glucosylceramidase beta 2 |
involved_in |
ISO |
(MGI:5661753|PMID:25803043) |
UniProt |
PMID:25803043 |
MGI:5661753 |
NCBI chrNW_004955472:553,556...564,411
Ensembl chrNW_004955472:553,556...564,411
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G |
Hax1 |
HCLS1 associated protein X-1 |
involved_in |
ISO |
(PMID:23001182) |
BHF-UCL |
PMID:23001182 |
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NCBI chrNW_004955545:816,789...819,667
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G |
Hcls1 |
hematopoietic cell-specific Lyn substrate 1 |
involved_in |
ISO |
(PMID:23001182) |
BHF-UCL |
PMID:23001182 |
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NCBI chrNW_004955427:20,999,934...21,020,401
Ensembl chrNW_004955427:20,999,485...21,020,531
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G |
Lats1 |
large tumor suppressor kinase 1 |
involved_in |
ISO |
(PMID:15220930) |
UniProt |
PMID:15220930 |
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NCBI chrNW_004955439:11,559,655...11,611,287
Ensembl chrNW_004955439:11,559,657...11,611,660
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G |
Pak3 |
p21 (RAC1) activated kinase 3 |
involved_in |
ISO |
(PMID:21177870) |
UniProt |
PMID:21177870 |
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NCBI chrNW_004955490:4,538,933...4,833,851
Ensembl chrNW_004955490:4,545,457...4,662,862
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G |
Pfn2 |
profilin 2 |
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ISO |
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RGD |
PMID:11027290 |
RGD:727303 |
NCBI chrNW_004955448:1,199,447...1,201,718
Ensembl chrNW_004955448:1,199,688...1,203,400
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G |
Pik3r2 |
phosphoinositide-3-kinase regulatory subunit 2 |
acts_upstream_of_or_within |
ISO |
(PMID:25217619) |
MGI |
PMID:25217619 |
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NCBI chrNW_004955524:3,234,111...3,241,445
Ensembl chrNW_004955524:3,234,111...3,241,173
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G |
Plekhg2 |
pleckstrin homology and RhoGEF domain containing G2 |
involved_in |
ISO |
(PMID:26573021) |
UniProt |
PMID:26573021 |
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NCBI chrNW_004955468:138,262...149,480
Ensembl chrNW_004955468:138,542...149,686
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G |
Ppp1r9a |
protein phosphatase 1 regulatory subunit 9A |
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ISO |
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RGD |
PMID:15473970 |
RGD:10043779 |
NCBI chrNW_004955432:11,607,269...11,891,568
Ensembl chrNW_004955432:11,608,382...11,886,044
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G |
Prex1 |
phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 |
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ISO |
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RGD |
PMID:18697831 |
RGD:2314615 |
NCBI chrNW_004955445:9,229,775...9,401,277
Ensembl chrNW_004955445:9,229,793...9,398,662
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G |
Rasa1 |
RAS p21 protein activator 1 |
involved_in |
ISO |
(PMID:8344248) |
UniProt |
PMID:8344248 |
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NCBI chrNW_004955418:23,807,740...23,897,699
Ensembl chrNW_004955418:23,807,740...23,897,707
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G |
Mtpn |
myotrophin |
involved_in |
ISO |
(PMID:16895918) |
UniProt |
PMID:16895918 |
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NCBI chrNW_004955494:6,805,518...6,844,454
Ensembl chrNW_004955494:6,805,262...6,845,394
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G |
Eml2 |
EMAP like 2 |
involved_in |
ISO |
(PMID:11694528) |
UniProt |
PMID:11694528 |
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NCBI chrNW_004955574:106,788...135,289
Ensembl chrNW_004955574:106,253...135,289
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G |
Nme7 |
NME/NM23 family member 7 |
involved_in |
ISO |
(PMID:24807905) |
UniProt |
PMID:24807905 |
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NCBI chrNW_004955462:7,879,754...8,073,207
Ensembl chrNW_004955462:7,880,157...8,073,186
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G |
Abl1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
involved_in |
ISO |
(PMID:24520051) |
UniProt |
PMID:24520051 |
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NCBI chrNW_004955513:652,048...799,182
Ensembl chrNW_004955513:653,252...799,239
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G |
Arl2 |
ADP ribosylation factor like GTPase 2 |
involved_in |
ISO |
(PMID:16525022) |
UniProt |
PMID:16525022 |
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NCBI chrNW_004955422:20,166,956...20,172,954
Ensembl chrNW_004955422:20,166,956...20,172,950
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G |
Camsap1 |
calmodulin regulated spectrin associated protein 1 |
involved_in |
ISO |
(PMID:24486153), (PMID:24706919) |
UniProt |
PMID:24486153 PMID:24706919 |
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NCBI chrNW_004955513:4,649,816...4,704,282
Ensembl chrNW_004955513:4,667,292...4,705,910
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G |
Camsap2 |
calmodulin regulated spectrin associated protein family member 2 |
involved_in |
ISO |
(PMID:24486153), (PMID:24706919) |
UniProt |
PMID:24486153 PMID:24706919 |
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NCBI chrNW_004955406:36,958,337...37,055,748
Ensembl chrNW_004955406:36,957,523...37,055,748
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G |
Camsap3 |
calmodulin regulated spectrin associated protein family member 3 |
involved_in |
ISO |
(PMID:24486153) (MGI:5565128|PMID:24706919) |
UniProt |
PMID:24486153 PMID:24706919 |
MGI:5565128 |
NCBI chrNW_004955563:1,639,369...1,648,826
Ensembl chrNW_004955563:1,639,600...1,648,818
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G |
Clasp2 |
cytoplasmic linker associated protein 2 |
involved_in |
ISO |
(PMID:24520051) |
UniProt |
PMID:24520051 |
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NCBI chrNW_004955421:767,648...957,160
Ensembl chrNW_004955421:767,210...897,457
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G |
Gba2 |
glucosylceramidase beta 2 |
involved_in |
ISO |
(MGI:5661753|PMID:25803043) |
UniProt |
PMID:25803043 |
MGI:5661753 |
NCBI chrNW_004955472:553,556...564,411
Ensembl chrNW_004955472:553,556...564,411
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G |
Mapre3 |
microtubule associated protein RP/EB family member 3 |
involved_in |
ISO |
(PMID:23159740) |
ARUK-UCL |
PMID:23159740 |
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NCBI chrNW_004955469:8,947,324...9,005,401
Ensembl chrNW_004955469:9,000,940...9,005,454
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G |
Prune1 |
prune exopolyphosphatase 1 |
involved_in |
ISO |
(PMID:28334956) |
UniProt |
PMID:28334956 |
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NCBI chrNW_004955588:379,793...408,441
Ensembl chrNW_004955588:382,425...407,020
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G |
Slain2 |
SLAIN motif family member 2 |
involved_in |
ISO |
(MGI:5052220|PMID:21646404) |
UniProt |
PMID:21646404 |
MGI:5052220 |
NCBI chrNW_004955443:134,631...231,866
Ensembl chrNW_004955443:131,696...231,866
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G |
Slc39a12 |
solute carrier family 39 member 12 |
acts_upstream_of_or_within |
ISO |
(PMID:23716681) |
MGI |
PMID:23716681 |
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NCBI chrNW_004955429:10,053,022...10,116,713
Ensembl chrNW_004955429:10,052,968...10,116,727
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G |
Gsn |
gelsolin |
involved_in |
ISO |
(PMID:19666531) |
UniProt |
PMID:19666531 |
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NCBI chrNW_004955419:6,682,202...6,733,361
Ensembl chrNW_004955419:6,682,058...6,733,361
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G |
Scin |
scinderin |
involved_in |
ISO |
(PMID:19666531) |
UniProt |
PMID:19666531 |
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NCBI chrNW_004955410:16,286,131...16,358,286
Ensembl chrNW_004955410:16,285,217...16,358,280
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G |
Tmsb4x |
thymosin beta 4 X-linked |
involved_in |
ISO |
(PMID:1447300), (PMID:1999398) |
CAFA |
PMID:1447300 PMID:1999398 |
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NCBI chrNW_004955544:266,397...268,447
Ensembl chrNW_004955544:266,397...268,447
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G |
Twf1 |
twinfilin actin binding protein 1 |
involved_in |
ISO |
(MGI:3840765|PMID:18837697) |
BHF-UCL |
PMID:18837697 |
MGI:3840765 |
NCBI chrNW_004955500:3,050,028...3,070,799
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G |
Twf2 |
twinfilin actin binding protein 2 |
involved_in |
ISO |
(MGI:3840765|PMID:18837697) |
BHF-UCL |
PMID:18837697 |
MGI:3840765 |
NCBI chrNW_004955532:3,835,620...3,844,760
Ensembl chrNW_004955532:3,834,579...3,844,760
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Term paths to the root
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