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ONTOLOGY REPORT - ANNOTATIONS


Term:cytoplasm to vacuole transport by the Cvt pathway
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Accession:GO:0032258 term browser browse the term
Definition:A cytoplasm to vacuole targeting pathway that uses machinery common with autophagy. The Cvt vesicle is formed when the receptor protein, Atg19, binds to the complexes of the target protein (aminopeptidase or alpha-mannosidase homododecamers), forming the Cvt complex. Atg11 binds to Atg9 and transports the Cvt complex to the pre-autophagosome (PAS). The phagophore membrane expands around the Cvt complex (excluding bulk cytoplasm) forming the Cvt vesicle. This pathway is mostly observed in yeast.
Synonyms:exact_synonym: cytoplasm to vacuole targeting;   protein localization by the Cvt pathway


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Path 1
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  biological_process 20014
    cellular process 18788
      process utilizing autophagic mechanism 464
        cytoplasm to vacuole transport by the Cvt pathway 0
          Cvt vesicle assembly 0
          regulation of protein localization by the Cvt pathway 0
Path 2
Term Annotations click to browse term
  biological_process 20014
    localization 6486
      establishment of localization 4918
        transport 4774
          nitrogen compound transport 2181
            amide transport 1841
              peptide transport 1807
                protein transport 1749
                  intracellular protein transport 1013
                    protein targeting 323
                      protein targeting to vacuole 44
                        cytoplasm to vacuole transport by the Cvt pathway 0
                          Cvt vesicle assembly 0
                          regulation of protein localization by the Cvt pathway 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.