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ONTOLOGY REPORT - ANNOTATIONS

Term:dense core granule localization
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Accession:GO:0032253 term browser browse the term
Definition:Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.
Synonyms:exact_synonym: dense core granule localisation;   dense core vesicle localization
 related_synonym: dense core granule clustering

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anterograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1a kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624847:4,961,552...5,035,125
Ensembl chrNW_004624847:4,961,552...5,035,061 		JBrowse link
G Kif1b kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624818:2,282,999...2,428,586
Ensembl chrNW_004624818:2,282,999...2,428,563 		JBrowse link
G Kif1c kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624786:8,845,352...8,868,681
Ensembl chrNW_004624786:8,845,033...8,869,577 		JBrowse link
G Sybu syntabulin ISO RGD PMID:17611281 RGD:13217407 NCBI chrNW_004624763:8,657,276...8,742,161
Ensembl chrNW_004624763:8,657,285...8,766,586 		JBrowse link
dense core granule cytoskeletal transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1a kinesin family member 1A involved_in ISO PMID:30021165
PMID:29166604		 UniProt PMID:29166604 PMID:30021165 RGD:14995321 RGD:15023486 NCBI chrNW_004624847:4,961,552...5,035,125
Ensembl chrNW_004624847:4,961,552...5,035,061 		JBrowse link
G Ppfia2 PTPRF interacting protein alpha 2 involved_in ISO (PMID:30021165) UniProt PMID:30021165 NCBI chrNW_004624837:627,484...1,116,597
Ensembl chrNW_004624837:629,302...1,111,081 		JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO PMID:29166604
(MGI:6104122|PMID:29166604)		 UniProt PMID:29166604 MGI:6104122 RGD:15023486 NCBI chrNW_004624779:17,593,760...17,603,217
Ensembl chrNW_004624779:17,592,669...17,603,403 		JBrowse link
G Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 involved_in ISO PMID:30021165 UniProt PMID:30021165 RGD:14995321 NCBI chrNW_004624849:452,848...946,511
Ensembl chrNW_004624849:452,884...940,686 		JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chrNW_004624908:418,248...464,203 JBrowse link
G Unc13b unc-13 homolog B NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chrNW_004624915:327,633...530,522
Ensembl chrNW_004624915:327,401...531,886 		JBrowse link
dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624888:2,985,966...3,443,542 JBrowse link
G Cadps2 calcium dependent secretion activator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624783:13,142,036...13,701,430
Ensembl chrNW_004624783:13,142,198...13,700,683 		JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624908:418,248...464,203 JBrowse link
G Unc13b unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624915:327,633...530,522
Ensembl chrNW_004624915:327,401...531,886 		JBrowse link
G Unc13d unc-13 homolog D involved_in ISO PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chrNW_004624801:5,720,998...5,736,122
Ensembl chrNW_004624801:5,721,391...5,736,294 		JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chrNW_004624779:17,593,760...17,603,217
Ensembl chrNW_004624779:17,592,669...17,603,403 		JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chrNW_004624908:418,248...464,203 JBrowse link
G Unc13b unc-13 homolog B involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chrNW_004624915:327,633...530,522
Ensembl chrNW_004624915:327,401...531,886 		JBrowse link
positive regulation of anterograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2 microtubule associated protein 2 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624765:6,476,544...6,758,959
Ensembl chrNW_004624765:6,476,346...6,546,116 		JBrowse link
G Mecp2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chrNW_004624946:620,581...685,339
Ensembl chrNW_004624946:628,284...685,246 		JBrowse link
G Trim46 tripartite motif containing 46 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624885:2,344,250...2,354,390
Ensembl chrNW_004624885:2,343,991...2,354,288 		JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO (MGI:3795609|PMID:18468511) ParkinsonsUK-UCL PMID:18468511 MGI:3795609 NCBI chrNW_004624779:17,593,760...17,603,217
Ensembl chrNW_004624779:17,592,669...17,603,403 		JBrowse link
positive regulation of retrograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chrNW_004624946:620,581...685,339
Ensembl chrNW_004624946:628,284...685,246 		JBrowse link
postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt6 synaptotagmin 6 involved_in ISO PMID:26216953 SynGO PMID:26216953 RGD:13702162 NCBI chrNW_004624772:9,753,485...9,810,815
Ensembl chrNW_004624772:9,753,416...9,810,757 		JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in ISO (MGI:5634021|PMID:25719439)
(PMID:25719439)		 SynGO PMID:25719439 MGI:5634021 NCBI chrNW_004624888:2,985,966...3,443,542 JBrowse link
G Snap25 synaptosome associated protein 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624741:11,218,259...11,303,406
Ensembl chrNW_004624741:11,274,490...11,302,813 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) SynGO PMID:11545717 MGI:3621672 NCBI chrNW_004624760:7,843,741...7,914,444
Ensembl chrNW_004624760:7,842,640...7,914,484 		JBrowse link
G Syt10 synaptotagmin 10 involved_in ISO (PMID:28683263) SynGO PMID:28683263 NCBI chrNW_004624778:2,700,545...2,763,134 JBrowse link
G Unc13a unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624908:418,248...464,203 JBrowse link
G Unc13b unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624915:327,633...530,522
Ensembl chrNW_004624915:327,401...531,886 		JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baiap3 BAI1 associated protein 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624913:2,045,702...2,060,092
Ensembl chrNW_004624913:2,045,721...2,060,092 		JBrowse link
regulation of dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO PMID:29166604 UniProt PMID:29166604 RGD:15023486 NCBI chrNW_004624928:1,442,216...1,494,275
Ensembl chrNW_004624928:1,439,146...1,494,266 		JBrowse link
regulation of postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO (PMID:19448629) SynGO PMID:19448629 NCBI chrNW_004624779:17,593,760...17,603,217
Ensembl chrNW_004624779:17,592,669...17,603,403 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in ISO PMID:24037803 SynGO PMID:24037803 RGD:13702177 NCBI chrNW_004624747:21,725,813...21,768,123
Ensembl chrNW_004624747:21,725,395...21,759,453 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO PMID:14627637 SynGO PMID:14627637 RGD:8554199 NCBI chrNW_004624828:1,165,877...1,174,306
Ensembl chrNW_004624828:1,165,327...1,174,417 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chrNW_004624908:1,532,857...1,537,159
Ensembl chrNW_004624908:1,530,312...1,536,129 		JBrowse link
G Unc13b unc-13 homolog B involved_in ISO PMID:31679900 SynGO PMID:31679900 RGD:155230690 NCBI chrNW_004624915:327,633...530,522
Ensembl chrNW_004624915:327,401...531,886 		JBrowse link
retrograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1a kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624847:4,961,552...5,035,125
Ensembl chrNW_004624847:4,961,552...5,035,061 		JBrowse link
G Kif1b kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624818:2,282,999...2,428,586
Ensembl chrNW_004624818:2,282,999...2,428,563 		JBrowse link
G Kif1c kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624786:8,845,352...8,868,681
Ensembl chrNW_004624786:8,845,033...8,869,577 		JBrowse link
G Kif5a kinesin family member 5A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624802:10,375,132...10,409,575
Ensembl chrNW_004624802:10,375,774...10,409,566 		JBrowse link
G Kif5b kinesin family member 5B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004624805:4,464,538...4,514,784
Ensembl chrNW_004624805:4,465,235...4,514,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15225
    localization 5008
      organelle localization 595
        vesicle localization 193
          secretory granule localization 31
            dense core granule localization 26
              dense core granule exocytosis + 14
              dense core granule transport + 13
              establishment of dense core granule localization 0
              maintenance of dense core granule location 0
paths to the root