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ONTOLOGY REPORT - ANNOTATIONS


Term:dense core granule localization
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Accession:GO:0032253 term browser browse the term
Definition:Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.
Synonyms:exact_synonym: dense core granule localisation;   dense core vesicle localization
 related_synonym: dense core granule clustering



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anterograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293
JBrowse link
G KIF1B kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
JBrowse link
G KIF1C kinesin family member 1C involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr17:4,997,950...5,028,401
Ensembl chr17:4,997,950...5,028,401
JBrowse link
G KIF5B kinesin family member 5B involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr10:32,009,015...32,056,425
Ensembl chr10:32,009,015...32,056,425
JBrowse link
G SYBU syntabulin involved_in ISO
IEA
RGD
Ensembl
PMID:17611281 GO_REF:0000107 RGD:13217407 NCBI chr 8:109,573,978...109,691,600
Ensembl chr 8:109,573,978...109,691,791
JBrowse link
dense core granule cytoskeletal transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISS UniProt GO_REF:0000024 NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293
JBrowse link
G PPFIA2 PTPRF interacting protein alpha 2 involved_in IMP (PMID:30021165) UniProt PMID:30021165 NCBI chr12:81,257,975...81,759,350
Ensembl chr12:81,257,975...81,759,553
JBrowse link
G SYT4 synaptotagmin 4 involved_in ISS
IEA
UniProt
Ensembl
GO_REF:0000024 GO_REF:0000107 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
G TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 involved_in ISS UniProt GO_REF:0000024 NCBI chr17:62,966,235...63,427,703
Ensembl chr17:62,966,235...63,427,703
JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UNC13A unc-13 homolog A NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chr19:17,601,336...17,688,354
Ensembl chr19:17,601,336...17,688,365
JBrowse link
G UNC13B unc-13 homolog B NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338
JBrowse link
dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADPS calcium dependent secretion activator involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:62,398,348...62,875,416
Ensembl chr 3:62,398,346...62,875,416
JBrowse link
G CADPS2 calcium dependent secretion activator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:122,318,411...122,886,460
Ensembl chr 7:122,318,411...122,886,759
JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UNC13A unc-13 homolog A involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:17,601,336...17,688,354
Ensembl chr19:17,601,336...17,688,365
JBrowse link
G UNC13B unc-13 homolog B involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338
JBrowse link
G UNC13C unc-13 homolog C involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:53,837,602...54,633,440
Ensembl chr15:53,978,201...54,628,707
JBrowse link
G UNC13D unc-13 homolog D involved_in ISO PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chr17:75,827,225...75,844,404
Ensembl chr17:75,827,225...75,844,785
JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UNC13A unc-13 homolog A involved_in ISS UniProt GO_REF:0000024 NCBI chr19:17,601,336...17,688,354
Ensembl chr19:17,601,336...17,688,365
JBrowse link
G UNC13B unc-13 homolog B involved_in ISS UniProt GO_REF:0000024 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338
JBrowse link
positive regulation of anterograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP2 microtubule associated protein 2 involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147
JBrowse link
G MECP2 methyl-CpG binding protein 2 involved_in ISO
IEA
RGD
Ensembl
PMID:22127389 GO_REF:0000107 RGD:12790715 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103
JBrowse link
G TRIM46 tripartite motif containing 46 involved_in IEA
ISS
Ensembl
ARUK-UCL
GO_REF:0000024 GO_REF:0000107 NCBI chr 1:155,173,849...155,184,971
Ensembl chr 1:155,173,787...155,184,971
JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
positive regulation of retrograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MECP2 methyl-CpG binding protein 2 involved_in ISO
IEA
RGD
Ensembl
PMID:22127389 GO_REF:0000107 RGD:12790715 NCBI chr  X:154,021,573...154,097,717
Ensembl chr  X:154,021,573...154,137,103
JBrowse link
postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT6 synaptotagmin 6 involved_in ISO PMID:26216953 SynGO PMID:26216953 RGD:13702162 NCBI chr 1:114,089,292...114,153,869
Ensembl chr 1:114,089,291...114,153,880
JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADPS calcium dependent secretion activator involved_in ISO (MGI:5634021|PMID:25719439)
(PMID:25719439)
SynGO PMID:25719439 MGI:5634021 NCBI chr 3:62,398,348...62,875,416
Ensembl chr 3:62,398,346...62,875,416
JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chr 6:71,886,550...72,403,145
Ensembl chr 6:71,886,550...72,403,150
JBrowse link
G SNAP25 synaptosome associated protein 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:10,218,830...10,307,418
Ensembl chr20:10,172,395...10,308,258
JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) SynGO PMID:11545717 MGI:3621672 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G SYT10 synaptotagmin 10 involved_in ISO (PMID:28683263) SynGO PMID:28683263 NCBI chr12:33,374,238...33,439,819
Ensembl chr12:33,374,238...33,439,819
JBrowse link
G UNC13A unc-13 homolog A involved_in IBA GO_Central GO_REF:0000033 NCBI chr19:17,601,336...17,688,354
Ensembl chr19:17,601,336...17,688,365
JBrowse link
G UNC13B unc-13 homolog B involved_in IBA GO_Central GO_REF:0000033 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338
JBrowse link
G UNC13C unc-13 homolog C involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:53,837,602...54,633,440
Ensembl chr15:53,978,201...54,628,707
JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAIAP3 BAI1 associated protein 3 involved_in IDA
IBA
(PMID:28626000) UniProt
GO_Central
PMID:28626000 GO_REF:0000033 NCBI chr16:1,333,645...1,349,439
Ensembl chr16:1,333,638...1,349,439
JBrowse link
regulation of dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO PMID:29166604 UniProt PMID:29166604 RGD:15023486 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
JBrowse link
regulation of postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:43,267,892...43,277,490
Ensembl chr18:43,267,892...43,277,535
JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RX7 purinergic receptor P2X 7 involved_in ISO PMID:24037803 SynGO PMID:24037803 RGD:13702177 NCBI chr12:121,132,876...121,188,032
Ensembl chr12:121,132,819...121,188,032
JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in ISO PMID:14627637 SynGO PMID:14627637 RGD:8554199 NCBI chr19:8,390,360...8,404,434
Ensembl chr19:8,389,981...8,404,434
JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:18,196,784...18,204,042
Ensembl chr19:18,196,784...18,204,042
JBrowse link
G UNC13B unc-13 homolog B involved_in ISO PMID:31679900 SynGO PMID:31679900 RGD:155230690 NCBI chr 9:35,162,009...35,405,335
Ensembl chr 9:35,161,992...35,405,338
JBrowse link
retrograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr 2:240,713,767...240,821,403
Ensembl chr 2:240,713,761...240,824,293
JBrowse link
G KIF1B kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
JBrowse link
G KIF1C kinesin family member 1C involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr17:4,997,950...5,028,401
Ensembl chr17:4,997,950...5,028,401
JBrowse link
G KIF5A kinesin family member 5A involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr12:57,550,044...57,586,633
Ensembl chr12:57,546,026...57,586,633
JBrowse link
G KIF5B kinesin family member 5B involved_in ISS ARUK-UCL GO_REF:0000024 NCBI chr10:32,009,015...32,056,425
Ensembl chr10:32,009,015...32,056,425
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19777
    localization 5914
      organelle localization 683
        vesicle localization 246
          secretory granule localization 33
            dense core granule localization 28
              dense core granule exocytosis + 16
              dense core granule transport + 13
              establishment of dense core granule localization 0
              maintenance of dense core granule location 0
paths to the root