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ONTOLOGY REPORT - ANNOTATIONS

Term:dense core granule localization
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Accession:GO:0032253 term browser browse the term
Definition:Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.
Synonyms:exact_synonym: dense core granule localisation;   dense core vesicle localization
 related_synonym: dense core granule clustering

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anterograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr10:126,784,843...126,890,649
Ensembl chr10:126,781,589...126,867,219 		JBrowse link
G KIF1B kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr20:121,393,478...121,567,704
Ensembl chr20:121,395,836...121,546,803 		JBrowse link
G KIF1C kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr16:4,478,315...4,502,261 JBrowse link
G SYBU syntabulin ISO RGD PMID:17611281 RGD:13217407 NCBI chr 8:104,274,092...104,390,051
Ensembl chr 8:104,273,217...104,344,348 		JBrowse link
dense core granule cytoskeletal transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISO PMID:30021165
PMID:29166604		 UniProt PMID:29166604 PMID:30021165 RGD:14995321 RGD:15023486 NCBI chr10:126,784,843...126,890,649
Ensembl chr10:126,781,589...126,867,219 		JBrowse link
G PPFIA2 PTPRF interacting protein alpha 2 involved_in ISO (PMID:30021165) UniProt PMID:30021165 NCBI chr11:76,740,204...77,237,990
Ensembl chr11:76,736,719...77,079,140 		JBrowse link
G SYT4 synaptotagmin 4 involved_in ISO PMID:29166604
(MGI:6104122|PMID:29166604)		 UniProt PMID:29166604 MGI:6104122 RGD:15023486 NCBI chr18:37,595,187...37,604,931
Ensembl chr18:37,595,035...37,606,007 		JBrowse link
G TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 involved_in ISO PMID:30021165 UniProt PMID:30021165 RGD:14995321 NCBI chr16:57,849,592...58,254,957
Ensembl chr16:57,855,282...58,306,571 		JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103219228 protein unc-13 homolog B NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chr12:45,230,661...45,461,934
Ensembl chr12:45,230,659...45,461,339 		JBrowse link
G UNC13A unc-13 homolog A NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chr 6:16,082,703...16,167,165
Ensembl chr 6:16,084,168...16,154,812 		JBrowse link
dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADPS calcium dependent secretion activator involved_in IEA InterPro GO_REF:0000002 NCBI chr22:23,471,616...23,948,694 JBrowse link
G CADPS2 calcium dependent secretion activator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr21:91,117,749...91,669,284 JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103219228 protein unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:45,230,661...45,461,934
Ensembl chr12:45,230,659...45,461,339 		JBrowse link
G UNC13A unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:16,082,703...16,167,165
Ensembl chr 6:16,084,168...16,154,812 		JBrowse link
G UNC13C unc-13 homolog C involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr26:28,806,368...29,196,031 JBrowse link
G UNC13D unc-13 homolog D involved_in ISO PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chr16:45,836,659...45,856,805
Ensembl chr16:45,838,175...45,857,201 		JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chr18:37,595,187...37,604,931
Ensembl chr18:37,595,035...37,606,007 		JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103219228 protein unc-13 homolog B involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chr12:45,230,661...45,461,934
Ensembl chr12:45,230,659...45,461,339 		JBrowse link
G UNC13A unc-13 homolog A involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chr 6:16,082,703...16,167,165
Ensembl chr 6:16,084,168...16,154,812 		JBrowse link
positive regulation of anterograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP2 microtubule associated protein 2 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr10:95,319,649...95,431,106
Ensembl chr10:95,349,157...95,431,320 		JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chr  X:128,445,028...128,519,892
Ensembl chr  X:128,453,577...128,455,785 		JBrowse link
G TRIM46 tripartite motif containing 46 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr20:8,647,598...8,659,674
Ensembl chr20:8,648,373...8,658,600 		JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO (MGI:3795609|PMID:18468511) ParkinsonsUK-UCL PMID:18468511 MGI:3795609 NCBI chr18:37,595,187...37,604,931
Ensembl chr18:37,595,035...37,606,007 		JBrowse link
positive regulation of retrograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chr  X:128,445,028...128,519,892
Ensembl chr  X:128,453,577...128,455,785 		JBrowse link
postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT6 synaptotagmin 6 involved_in ISO PMID:26216953 SynGO PMID:26216953 RGD:13702162 NCBI chr20:19,497,218...19,561,621
Ensembl chr20:19,512,540...19,563,038 		JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADPS calcium dependent secretion activator involved_in ISO (MGI:5634021|PMID:25719439)
(PMID:25719439)		 SynGO PMID:25719439 MGI:5634021 NCBI chr22:23,471,616...23,948,694 JBrowse link
G LOC103219228 protein unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr12:45,230,661...45,461,934
Ensembl chr12:45,230,659...45,461,339 		JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chr17:2,690,430...3,176,794
Ensembl chr17:2,690,418...3,176,738 		JBrowse link
G SNAP25 synaptosome associated protein 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:27,857,093...27,944,487
Ensembl chr 2:27,858,319...27,944,496 		JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) SynGO PMID:11545717 MGI:3621672 NCBI chr12:10,440,061...10,519,798
Ensembl chr12:10,439,801...10,519,777 		JBrowse link
G SYT10 synaptotagmin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:32,846,425...32,914,946
Ensembl chr11:32,850,902...32,914,464 		JBrowse link
G UNC13A unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:16,082,703...16,167,165
Ensembl chr 6:16,084,168...16,154,812 		JBrowse link
G UNC13C unc-13 homolog C involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr26:28,806,368...29,196,031 JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAIAP3 BAI1 associated protein 3 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 5:1,222,994...1,237,823
Ensembl chr 5:1,227,910...1,236,898 		JBrowse link
regulation of dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO PMID:29166604 UniProt PMID:29166604 RGD:15023486 NCBI chr 9:43,356,603...43,489,066
Ensembl chr 9:43,356,308...43,393,425 		JBrowse link
regulation of postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO (PMID:19448629) SynGO PMID:19448629 NCBI chr18:37,595,187...37,604,931
Ensembl chr18:37,595,035...37,606,007 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103219228 protein unc-13 homolog B involved_in ISO PMID:31679900 SynGO PMID:31679900 RGD:155230690 NCBI chr12:45,230,661...45,461,934
Ensembl chr12:45,230,659...45,461,339 		JBrowse link
G P2RX7 purinergic receptor P2X 7 involved_in ISO PMID:24037803 SynGO PMID:24037803 RGD:13702177 NCBI chr11:116,505,975...116,560,151
Ensembl chr11:116,529,346...116,563,059 		JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in ISO PMID:14627637 SynGO PMID:14627637 RGD:8554199 NCBI chr 6:7,743,130...7,757,237
Ensembl chr 6:7,743,361...7,757,305 		JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:16,671,388...16,678,780
Ensembl chr 6:16,670,431...16,678,644 		JBrowse link
retrograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr10:126,784,843...126,890,649
Ensembl chr10:126,781,589...126,867,219 		JBrowse link
G KIF1B kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr20:121,393,478...121,567,704
Ensembl chr20:121,395,836...121,546,803 		JBrowse link
G KIF1C kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr16:4,478,315...4,502,261 JBrowse link
G KIF5A kinesin family member 5A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr11:53,458,795...53,493,801 JBrowse link
G KIF5B kinesin family member 5B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 9:31,321,615...31,369,549
Ensembl chr 9:31,320,549...31,369,519 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17080
    localization 5434
      organelle localization 631
        vesicle localization 205
          secretory granule localization 33
            dense core granule localization 28
              dense core granule exocytosis + 16
              dense core granule transport + 13
              establishment of dense core granule localization 0
              maintenance of dense core granule location 0
paths to the root