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ONTOLOGY REPORT - ANNOTATIONS

Term:secretory granule localization
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Accession:GO:0032252 term browser browse the term
Definition:Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.
Synonyms:exact_synonym: secretory granule localisation
 related_synonym: secretory granule clustering

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secretory granule localization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Myo5a myosin VA acts_upstream_of_or_within ISO (PMID:15788565) RGD
MGI		 PMID:12615975 PMID:15788565 PMID:16190983 RGD:1298991 RGD:1600832 NCBI chrNW_004955409:2,409,503...2,530,539
Ensembl chrNW_004955409:2,428,815...2,530,012 		JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:19549714 RGD:2324863 NCBI chrNW_004955410:11,402,476...11,433,335
Ensembl chrNW_004955410:11,402,520...11,437,422 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 acts_upstream_of_or_within ISO (PMID:17190838) MGI PMID:17190838 NCBI chrNW_004955416:5,494,030...5,561,608
Ensembl chrNW_004955416:5,494,030...5,561,614 		JBrowse link
G Tcf7l2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19168596) MGI PMID:19168596 NCBI chrNW_004955431:18,020,309...18,207,926
Ensembl chrNW_004955431:18,020,409...18,209,134 		JBrowse link
G Uso1 USO1 vesicle transport factor acts_upstream_of_or_within ISO (PMID:15800058) MGI PMID:15800058 NCBI chrNW_004955474:1,647,670...1,704,869
Ensembl chrNW_004955474:1,647,361...1,705,548 		JBrowse link
anterograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1a kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955542:756,834...832,805
Ensembl chrNW_004955542:756,835...832,889 		JBrowse link
G Kif1b kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955486:3,366,791...3,503,845
Ensembl chrNW_004955486:3,370,596...3,489,052 		JBrowse link
G Kif1c kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955467:10,399,768...10,423,249
Ensembl chrNW_004955467:10,399,768...10,422,712 		JBrowse link
G Sybu syntabulin ISO RGD PMID:17611281 RGD:13217407 NCBI chrNW_004955417:16,971,394...17,036,925
Ensembl chrNW_004955417:16,971,394...17,036,940 		JBrowse link
dense core granule cytoskeletal transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1a kinesin family member 1A involved_in ISO PMID:30021165
PMID:29166604		 UniProt PMID:29166604 PMID:30021165 RGD:14995321 RGD:15023486 NCBI chrNW_004955542:756,834...832,805
Ensembl chrNW_004955542:756,835...832,889 		JBrowse link
G Ppfia2 PTPRF interacting protein alpha 2 involved_in ISO (PMID:30021165) UniProt PMID:30021165 NCBI chrNW_004955405:19,837,749...20,291,666
Ensembl chrNW_004955405:19,839,092...20,286,578 		JBrowse link
G Syt4 synaptotagmin 4 involved_in ISO PMID:29166604
(MGI:6104122|PMID:29166604)		 UniProt PMID:29166604 MGI:6104122 RGD:15023486 NCBI chrNW_004955402:29,195,124...29,204,816
Ensembl chrNW_004955402:29,193,455...29,204,975 		JBrowse link
G Tanc2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 involved_in ISO PMID:30021165 UniProt PMID:30021165 RGD:14995321 NCBI chrNW_004955478:8,370,813...8,757,132
Ensembl chrNW_004955478:8,376,487...8,757,136 		JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chrNW_004955524:725,353...769,745 JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A involved_in ISO PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chrNW_004955524:725,353...769,745 JBrowse link
G Unc13d unc-13 homolog D involved_in ISO PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chrNW_004955506:6,407,073...6,423,406
Ensembl chrNW_004955506:6,407,723...6,423,406 		JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chrNW_004955402:29,195,124...29,204,816
Ensembl chrNW_004955402:29,193,455...29,204,975 		JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Unc13a unc-13 homolog A involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chrNW_004955524:725,353...769,745 JBrowse link
positive regulation of anterograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Map2 microtubule associated protein 2 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955457:5,678,826...5,816,114
Ensembl chrNW_004955457:5,678,436...5,875,024 		JBrowse link
G Mecp2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chrNW_004955580:674,014...737,586
Ensembl chrNW_004955580:679,109...735,288 		JBrowse link
G Trim46 tripartite motif containing 46 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955545:1,646,244...1,656,825
Ensembl chrNW_004955545:1,646,244...1,656,825 		JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO (MGI:3795609|PMID:18468511) ParkinsonsUK-UCL PMID:18468511 MGI:3795609 NCBI chrNW_004955402:29,195,124...29,204,816
Ensembl chrNW_004955402:29,193,455...29,204,975 		JBrowse link
positive regulation of retrograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mecp2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chrNW_004955580:674,014...737,586
Ensembl chrNW_004955580:679,109...735,288 		JBrowse link
postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt6 synaptotagmin 6 involved_in ISO PMID:26216953 SynGO PMID:26216953 RGD:13702162 NCBI chrNW_004955435:17,349,971...17,405,526
Ensembl chrNW_004955435:17,347,011...17,405,526 		JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in ISO (MGI:5634021|PMID:25719439)
(PMID:25719439)		 SynGO PMID:25719439 MGI:5634021 NCBI chrNW_004955517:2,965,471...3,420,183 JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chrNW_004955488:6,999,128...7,196,583
Ensembl chrNW_004955488:6,936,952...7,197,022 		JBrowse link
G Snap25 synaptosome associated protein 25 involved_in ISO (PMID:28404788) SynGO PMID:28404788 NCBI chrNW_004955415:20,133,361...20,218,840
Ensembl chrNW_004955415:20,133,201...20,219,023 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) SynGO PMID:11545717 MGI:3621672 NCBI chrNW_004955419:963,829...1,000,759
Ensembl chrNW_004955419:963,829...1,000,759 		JBrowse link
G Syt10 synaptotagmin 10 involved_in ISO (PMID:28683263) SynGO PMID:28683263 NCBI chrNW_004955505:2,392,086...2,449,528
Ensembl chrNW_004955505:2,403,055...2,449,528 		JBrowse link
G Unc13a unc-13 homolog A involved_in ISO (MGI:5819330|PMID:26575293) SynGO PMID:26575293 MGI:5819330 NCBI chrNW_004955524:725,353...769,745 JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Baiap3 BAI1 associated protein 3 involved_in ISO (PMID:28626000) UniProt PMID:28626000 NCBI chrNW_004955442:15,884,034...15,897,894
Ensembl chrNW_004955442:15,884,034...15,898,396 		JBrowse link
regulation of dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mapk8 mitogen-activated protein kinase 8 involved_in ISO PMID:29166604 UniProt PMID:29166604 RGD:15023486 NCBI chrNW_004955556:1,593,552...1,705,543
Ensembl chrNW_004955556:1,593,494...1,665,784 		JBrowse link
regulation of postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt4 synaptotagmin 4 involved_in ISO (PMID:19448629) SynGO PMID:19448629 NCBI chrNW_004955402:29,195,124...29,204,816
Ensembl chrNW_004955402:29,193,455...29,204,975 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in ISO PMID:24037803 SynGO PMID:24037803 RGD:13702177 NCBI chrNW_004955482:7,048,674...7,087,525
Ensembl chrNW_004955482:7,048,776...7,086,926 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in ISO PMID:14627637 SynGO PMID:14627637 RGD:8554199 NCBI chrNW_004955563:1,008,267...1,017,315
Ensembl chrNW_004955563:1,008,769...1,017,315 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chrNW_004955524:3,220,108...3,224,376
Ensembl chrNW_004955524:3,221,366...3,224,376 		JBrowse link
retrograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kif1a kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955542:756,834...832,805
Ensembl chrNW_004955542:756,835...832,889 		JBrowse link
G Kif1b kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955486:3,366,791...3,503,845
Ensembl chrNW_004955486:3,370,596...3,489,052 		JBrowse link
G Kif1c kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955467:10,399,768...10,423,249
Ensembl chrNW_004955467:10,399,768...10,422,712 		JBrowse link
G Kif5a kinesin family member 5A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955458:5,264,274...5,310,962
Ensembl chrNW_004955458:5,287,111...5,310,962 		JBrowse link
G Kif5b kinesin family member 5B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chrNW_004955429:23,632,246...23,678,797
Ensembl chrNW_004955429:23,631,282...23,678,562 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12483
    localization 4339
      organelle localization 522
        vesicle localization 172
          secretory granule localization 30
            dense core granule localization + 25
            establishment of secretory granule localization + 0
            maintenance of secretory granule location + 0
paths to the root