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ONTOLOGY REPORT - ANNOTATIONS


Term:secretory granule localization
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Accession:GO:0032252 term browser browse the term
Definition:Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.
Synonyms:exact_synonym: secretory granule localisation
 related_synonym: secretory granule clustering



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secretory granule localization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYO5A myosin VA acts_upstream_of_or_within ISO (PMID:15788565) RGD
MGI
PMID:12615975 PMID:15788565 PMID:16190983 RGD:1298991 RGD:1600832 NCBI chr15:31,246,192...31,470,040
Ensembl chr15:49,578,491...49,704,319
JBrowse link
G PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma ISO RGD PMID:19549714 RGD:2324863 NCBI chr 7:98,841,974...98,885,446
Ensembl chr 7:111,570,148...111,611,614
JBrowse link
G RASGRP1 RAS guanyl releasing protein 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:17190838) Ensembl
MGI
PMID:17190838 GO_REF:0000107 NCBI chr15:17,417,684...17,494,333
Ensembl chr15:35,675,348...35,750,315
JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19168596) MGI PMID:19168596 NCBI chr10:109,541,524...109,759,499
Ensembl chr10:112,978,167...113,192,281
JBrowse link
G USO1 USO1 vesicle transport factor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:15800058) Ensembl
MGI
PMID:15800058 GO_REF:0000107 NCBI chr 4:48,391,293...48,480,909
Ensembl chr 4:54,229,601...54,317,158
JBrowse link
anterograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr2B:127,969,494...128,078,282
Ensembl chr2B:246,778,679...246,860,326
JBrowse link
G KIF1B kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 1:8,969,910...9,141,964
Ensembl chr 1:10,198,997...10,364,577
Ensembl chr 1:10,198,997...10,364,577
JBrowse link
G KIF1C kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr17:5,046,488...5,073,220
Ensembl chr17:5,035,014...5,061,957
JBrowse link
G SYBU syntabulin ISO RGD PMID:17611281 RGD:13217407 NCBI chr 8:106,223,046...106,340,418
Ensembl chr 8:108,368,117...108,483,927
JBrowse link
dense core granule cytoskeletal transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISO PMID:30021165
PMID:29166604
UniProt PMID:29166604 PMID:30021165 RGD:14995321 RGD:15023486 NCBI chr2B:127,969,494...128,078,282
Ensembl chr2B:246,778,679...246,860,326
JBrowse link
G PPFIA2 PTPRF interacting protein alpha 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:78,768,756...79,271,630
Ensembl chr12:81,879,812...82,376,917
JBrowse link
G SYT4 synaptotagmin 4 involved_in ISO PMID:29166604
(MGI:6104122|PMID:29166604)
UniProt PMID:29166604 MGI:6104122 RGD:15023486 NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721
JBrowse link
G TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 involved_in ISO PMID:30021165 UniProt PMID:30021165 RGD:14995321 NCBI chr17:57,037,330...57,509,229
Ensembl chr17:62,239,230...62,650,299
JBrowse link
dense core granule docking term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UNC13A unc-13 homolog A NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642
JBrowse link
G UNC13B unc-13 homolog B NOT|involved_in ISO (MGI:5819330|PMID:26575293) SynGO-UCL PMID:26575293 MGI:5819330 NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894
JBrowse link
dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADPS calcium dependent secretion activator involved_in IEA InterPro GO_REF:0000002 NCBI chr 3:62,321,496...62,797,298 JBrowse link
G CADPS2 calcium dependent secretion activator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chr 7:114,328,933...114,896,388
Ensembl chr 7:127,014,772...127,579,249
JBrowse link
dense core granule priming term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UNC13A unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642
JBrowse link
G UNC13B unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894
JBrowse link
G UNC13D unc-13 homolog D involved_in ISO PMID:26575293 SynGO-UCL PMID:26575293 RGD:12050107 NCBI chr17:69,777,570...69,794,877
Ensembl chr17:75,328,572...75,344,842
JBrowse link
negative regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO PMID:20303854 ParkinsonsUK-UCL PMID:20303854 RGD:11541109 NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721
JBrowse link
neuronal dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G UNC13A unc-13 homolog A involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642
JBrowse link
G UNC13B unc-13 homolog B involved_in ISO (MGI:5476894|PMID:23229896) UniProt PMID:23229896 MGI:5476894 NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894
JBrowse link
positive regulation of anterograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP2 microtubule associated protein 2 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr2B:96,681,268...96,991,650
Ensembl chr2B:215,314,857...215,391,728
JBrowse link
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
G TRIM46 tripartite motif containing 46 involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 1:130,521,472...130,532,636
Ensembl chr 1:134,129,984...134,142,362
JBrowse link
positive regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO (MGI:3795609|PMID:18468511) ParkinsonsUK-UCL PMID:18468511 MGI:3795609 NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721
JBrowse link
positive regulation of retrograde dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MECP2 methyl-CpG binding protein 2 ISO RGD PMID:22127389 RGD:12790715 NCBI chr  X:143,571,864...143,647,192
Ensembl chr  X:153,465,204...153,527,854
JBrowse link
postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT6 synaptotagmin 6 involved_in ISO PMID:26216953 SynGO PMID:26216953 RGD:13702162 NCBI chr 1:88,397,809...88,467,493
Ensembl chr 1:123,452,889...123,514,795
JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CADPS calcium dependent secretion activator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:62,321,496...62,797,298 JBrowse link
G RIMS1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) SynGO PMID:31679900 NCBI chr 6:69,714,807...70,231,260
Ensembl chr 6:73,008,176...73,523,422
JBrowse link
G SNAP25 synaptosome associated protein 25 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:10,164,236...10,252,856
Ensembl chr20:10,218,358...10,252,841
JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in ISO (MGI:3621672|PMID:11545717) SynGO PMID:11545717 MGI:3621672 NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152
JBrowse link
G SYT10 synaptotagmin 10 involved_in ISO (PMID:28683263) SynGO PMID:28683263 NCBI chr12:52,761,294...52,830,221
Ensembl chr12:55,364,714...55,429,298
JBrowse link
G UNC13A unc-13 homolog A involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:17,088,654...17,175,559
Ensembl chr19:18,068,006...18,150,642
JBrowse link
G UNC13B unc-13 homolog B involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894
JBrowse link
regulation of dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAIAP3 BAI1 associated protein 3 involved_in IEA Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118 Ensembl chr16:1,390,160...1,403,978 JBrowse link
regulation of dense core granule transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAPK8 mitogen-activated protein kinase 8 involved_in ISO PMID:29166604 UniProt PMID:29166604 RGD:15023486 NCBI chr10:45,806,748...45,936,362 JBrowse link
regulation of postsynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SYT4 synaptotagmin 4 involved_in ISO (PMID:19448629) SynGO PMID:19448629 NCBI chr18:36,540,756...36,550,439
Ensembl chr18:40,089,938...40,099,721
JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2RX7 purinergic receptor P2X 7 involved_in ISO PMID:24037803 SynGO PMID:24037803 RGD:13702177 NCBI chr12:118,731,761...118,786,039
Ensembl chr12:122,102,888...122,154,068
JBrowse link
G RAB11B RAB11B, member RAS oncogene family involved_in ISO PMID:14627637 SynGO PMID:14627637 RGD:8554199 NCBI chr19:7,676,095...7,690,177 JBrowse link
G RAB3A RAB3A, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:17,672,661...17,679,541
Ensembl chr19:18,649,166...18,656,768
JBrowse link
G UNC13B unc-13 homolog B involved_in ISO PMID:31679900 SynGO PMID:31679900 RGD:155230690 NCBI chr 9:35,011,350...35,255,148
Ensembl chr 9:35,817,353...36,059,894
JBrowse link
retrograde neuronal dense core vesicle transport term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KIF1A kinesin family member 1A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr2B:127,969,494...128,078,282
Ensembl chr2B:246,778,679...246,860,326
JBrowse link
G KIF1B kinesin family member 1B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr 1:8,969,910...9,141,964
Ensembl chr 1:10,198,997...10,364,577
Ensembl chr 1:10,198,997...10,364,577
JBrowse link
G KIF1C kinesin family member 1C involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr17:5,046,488...5,073,220
Ensembl chr17:5,035,014...5,061,957
JBrowse link
G KIF5A kinesin family member 5A involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr12:31,340,201...31,376,849
Ensembl chr12:31,599,376...31,635,327
JBrowse link
G KIF5B kinesin family member 5B involved_in ISO PMID:28426968 ARUK-UCL PMID:28426968 RGD:13514087 NCBI chr10:32,138,964...32,186,448
Ensembl chr10:32,731,150...32,778,242
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16768
    localization 5348
      organelle localization 638
        vesicle localization 205
          secretory granule localization 32
            dense core granule localization + 27
            establishment of secretory granule localization + 0
            maintenance of secretory granule location + 0
paths to the root