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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of actin filament bundle assembly
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Accession:GO:0032232 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.
Synonyms:exact_synonym: down regulation of actin filament bundle formation;   downregulation of actin filament bundle formation
 narrow_synonym: inhibition of actin filament bundle formation


show annotations for term's descendants           Sort by:
negative regulation of actin filament bundle assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cfl1 cofilin 1 IMP RGD PMID:24093776 RGD:11570550 NCBI chr 1:212,227,124...212,230,656
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Dbn1 drebrin 1 IDA RGD PMID:8769857 RGD:2317774 NCBI chr17:9,155,729...9,170,121
Ensembl chr17:9,150,659...9,164,984 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA prevents phenylephrine-induced actin organization RGD PMID:9155015 RGD:2293527 NCBI chr 2:45,081,889...45,150,555
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:17512523)
GO_REF:0000107		 RGD
Ensembl		 PMID:17512523 GO_REF:0000107 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Shank1 SH3 and multiple ankyrin repeat domains 1 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19208628)		 BHF-UCL
Ensembl
RGD		 PMID:19208628 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:103,944,416...103,993,887
Ensembl chr 1:94,808,276...94,855,824 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 involved_in
acts_upstream_of_or_within		 ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19208628)		 BHF-UCL
Ensembl
RGD		 PMID:19208628 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:122,448,323...122,518,623
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
negative regulation of stress fiber assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 involved_in ISO
IEA		 (PMID:11804590)
GO_REF:0000107		 RGD
Ensembl		 PMID:11804590 GO_REF:0000107 NCBI chr 1:165,160,701...165,226,219
Ensembl chr 1:155,748,652...155,814,184 		JBrowse link
G Arhgap28 Rho GTPase activating protein 28 involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 GO_REF:0000033
(PMID:25211221)
GO_REF:0000107		 GO_Central
RGD
Ensembl		 PMID:25211221 GO_REF:0000033 GO_REF:0000107 NCBI chr 9:107,832,584...107,998,030
Ensembl chr 9:107,833,330...107,998,000 		JBrowse link
G Arhgap6 Rho GTPase activating protein 6 involved_in ISO
IEA		 (PMID:10699171)
GO_REF:0000107		 RGD
Ensembl		 PMID:10699171 GO_REF:0000107 NCBI chr  X:28,525,912...29,062,344
Ensembl chr  X:24,953,464...25,488,663 		JBrowse link
G Arhgef18 Rho/Rac guanine nucleotide exchange factor 18 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr12:6,192,958...6,300,997
Ensembl chr12:1,395,088...1,503,081 		JBrowse link
G Cgnl1 cingulin-like 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 8:72,273,401...72,424,842
Ensembl chr 8:72,275,645...72,422,917 		JBrowse link
G Clasp1 cytoplasmic linker associated protein 1 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr13:32,046,362...32,267,954
Ensembl chr13:29,493,596...29,715,146 		JBrowse link
G Clasp2 cytoplasmic linker associated protein 2 involved_in ISO (PMID:24859005) RGD PMID:24859005 NCBI chr 8:122,555,532...122,736,934
Ensembl chr 8:113,677,284...113,858,731 		JBrowse link
G Coro2b coronin 2B acts_upstream_of_or_within ISO
IEA		 MGI:4419137 (PMID:29162887)
GO_REF:0000107		 RGD
Ensembl		 PMID:29162887 GO_REF:0000107 NCBI chr 8:62,906,861...63,017,295
Ensembl chr 8:62,906,867...63,017,302 		JBrowse link
G Dlc1 DLC1 Rho GTPase activating protein involved_in ISO
IEA		 (PMID:17932950)
GO_REF:0000107		 RGD
Ensembl		 PMID:17932950 GO_REF:0000107 NCBI chr16:61,954,177...62,374,819
Ensembl chr16:55,291,584...55,671,439 		JBrowse link
G F11r F11 receptor involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr13:86,406,229...86,429,819
Ensembl chr13:83,873,797...83,897,402 		JBrowse link
G Frmd7 FERM domain containing 7 acts_upstream_of_or_within ISO
IEA		 (PMID:23967341)
GO_REF:0000107		 RGD
Ensembl		 PMID:23967341 GO_REF:0000107 NCBI chr  X:130,375,925...130,423,836
Ensembl chr  X:130,377,227...130,423,771 		JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in ISO
IEA		 (PMID:12556481)
GO_REF:0000107		 RGD
Ensembl		 PMID:12556481 GO_REF:0000107 NCBI chr10:60,974,183...60,995,047
Ensembl chr10:60,475,897...60,496,773 		JBrowse link
G Met MET proto-oncogene, receptor tyrosine kinase involved_in ISO
IEA		 (PMID:25198505)
GO_REF:0000107		 RGD
Ensembl		 PMID:25198505 GO_REF:0000107 NCBI chr 4:46,756,823...46,864,041
Ensembl chr 4:45,790,791...45,897,876 		JBrowse link
G Mir138-1 microRNA 138-1 involved_in ISO (PMID:20232393) RGD PMID:20232393 NCBI chr 8:131,178,434...131,178,532
Ensembl chr 8:122,300,966...122,301,064 		JBrowse link
G Mir138-2 microRNA 138-2 involved_in ISO (PMID:20232393) RGD PMID:20232393 NCBI chr19:10,680,133...10,680,214
Ensembl chr19:10,674,193...10,674,274 		JBrowse link
G Mir20a microRNA 20a involved_in ISO (PMID:22696064) RGD PMID:22696064 NCBI chr15:98,588,303...98,588,387
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir21 microRNA 21 involved_in ISO (PMID:21347332) RGD PMID:21347332 NCBI chr10:71,902,600...71,902,691
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Myoc myocilin involved_in ISO
IEA
ISS		 (PMID:17984096)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:17984096 GO_REF:0000024 GO_REF:0000107 NCBI chr13:77,509,963...77,520,361
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 IDA RGD PMID:21712390 RGD:7245493 NCBI chr 2:184,762,242...184,765,176
Ensembl chr 2:182,073,215...182,082,399 		JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 involved_in ISO
IEA		 (PMID:25753039)
GO_REF:0000107		 RGD
Ensembl		 PMID:25753039 GO_REF:0000107 NCBI chr11:82,212,896...82,273,803
Ensembl chr11:68,707,969...68,768,816 		JBrowse link
G Pfn1 profilin 1 involved_in ISO
IEA		 (PMID:23153535)
GO_REF:0000107		 RGD
Ensembl		 PMID:23153535 GO_REF:0000107 NCBI chr10:55,863,882...55,866,587
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 involved_in ISO
IEA		 (PMID:24859005)
GO_REF:0000107		 RGD
Ensembl		 PMID:24859005 GO_REF:0000107 NCBI chr11:68,321,738...68,540,724
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 involved_in ISO (PMID:11038173) RGD PMID:11038173 NCBI chr 2:34,612,946...34,697,660
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 acts_upstream_of_or_within ISO
IEA		 (PMID:22266902)
GO_REF:0000107		 RGD
Ensembl		 PMID:22266902 GO_REF:0000107 NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:12052877 RGD:1299363 NCBI chr 4:33,936,949...34,258,927
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Rhpn1 rhophilin, Rho GTPase binding protein 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
(PMID:25071083)		 GO_Central
RGD		 PMID:25071083 GO_REF:0000033 NCBI chr 7:107,391,948...107,402,713
Ensembl chr 7:107,391,984...107,402,713 		JBrowse link
G Rhpn2 rhophilin, Rho GTPase binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IBA
IEA		 (PMID:25071083)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:25071083 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:97,128,054...97,188,803
Ensembl chr 1:87,991,144...88,051,902 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:11094076 RGD:1581790 NCBI chr 2:206,309,715...206,314,070
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Stmn1 stathmin 1 involved_in ISO
IEA		 (PMID:25198505)
GO_REF:0000107		 RGD
Ensembl		 PMID:25198505 GO_REF:0000107 NCBI chr 5:151,964,308...151,970,843
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Tacstd2 tumor-associated calcium signal transducer 2 involved_in IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(PMID:22194864)		 Ensembl
UniProt
RGD		 PMID:22194864 GO_REF:0000024 GO_REF:0000107 NCBI chr 4:98,037,620...98,039,320
Ensembl chr 4:96,707,951...96,709,650 		JBrowse link
G Tjp1 tight junction protein 1 involved_in ISO (PMID:25753039) RGD PMID:25753039 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 acts_upstream_of_or_within ISO
IEA		 (PMID:24632071)
GO_REF:0000107		 RGD
Ensembl		 PMID:24632071 GO_REF:0000107 NCBI chr 9:57,937,873...58,225,372
Ensembl chr 9:50,436,079...50,733,475 		JBrowse link
G Tmsb15b2 thymosin beta 15B2 acts_upstream_of_or_within ISO (PMID:19233202) RGD PMID:19233202 NCBI chr  X:100,298,705...100,300,820
Ensembl chr  X:100,298,514...100,300,886 		JBrowse link
G Was WASP actin nucleation promoting factor involved_in ISO
IEA		 (PMID:8625410)
GO_REF:0000107		 RGD
Ensembl		 PMID:8625410 GO_REF:0000107 NCBI chr  X:17,077,057...17,085,802
Ensembl chr  X:14,405,124...14,413,849 		JBrowse link
G Wasf2 WASP family member 2 involved_in ISO
IEA		 (PMID:21107423)
GO_REF:0000107		 RGD
Ensembl		 PMID:21107423 GO_REF:0000107 NCBI chr 5:150,620,733...150,685,943
Ensembl chr 5:145,336,842...145,399,242 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      regulation of cellular process 13038
        regulation of cellular component biogenesis 1154
          regulation of actin filament bundle assembly 119
            negative regulation of actin filament bundle assembly 41
              negative regulation of formin-nucleated actin cable assembly 0
              negative regulation of stress fiber assembly 35
Path 2
Term Annotations click to browse term
  biological_process 20567
    cellular process 19557
      cellular component organization or biogenesis 7115
        cellular component organization 6828
          organelle organization 3714
            cytoskeleton organization 1595
              actin cytoskeleton organization 770
                actin filament organization 501
                  actin filament bundle organization 190
                    actin filament bundle assembly 187
                      regulation of actin filament bundle assembly 119
                        negative regulation of actin filament bundle assembly 41
                          negative regulation of formin-nucleated actin cable assembly 0
                          negative regulation of stress fiber assembly 35
paths to the root