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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of synaptic transmission, cholinergic
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Accession:GO:0032222 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.


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regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Camk2b calcium/calmodulin-dependent protein kinase II beta ISO (MGI:MGI:4352609|PMID:19332541) RGD PMID:19332541 MGI:MGI:4352609 NCBI chr14:86,208,876...86,297,727
Ensembl chr14:86,208,901...86,297,652
JBrowse link
negative regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr6 5-hydroxytryptamine receptor 6 IMP RGD PMID:16987217 RGD:2317005 NCBI chr 5:157,501,202...157,518,870
Ensembl chr 5:157,503,040...157,518,631
JBrowse link
positive regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2a adenosine A2a receptor IMP phrenic nerve terminals in the presence of adenosine transport inhibitor deoxycoformycin RGD PMID:12679375 RGD:1625693 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873
JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C IMP RGD PMID:15266551 RGD:1625007 NCBI chr  X:118,084,520...118,318,040
Ensembl chr  X:118,084,890...118,318,039
JBrowse link
G Tacr2 tachykinin receptor 2 IMP RGD PMID:12747940 RGD:5147477 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
JBrowse link
positive regulation of synaptic transmission, cholinergic term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma IDA RGD PMID:1900518 RGD:2311499 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Lama2 laminin subunit alpha 2 ISO MGI:MGI:1856026 (MGI:MGI:77287|PMID:8568931) RGD PMID:8568931 MGI:MGI:77287 NCBI chr 1:18,491,264...19,143,486
Ensembl chr 1:18,491,384...19,143,269
JBrowse link
G Musk muscle associated receptor tyrosine kinase IMP RGD PMID:16870737 RGD:2317092 NCBI chr 5:75,392,790...75,498,694
Ensembl chr 5:75,392,790...75,498,694
JBrowse link
G Ngfr nerve growth factor receptor IMP medial septum and diagonal band of Broca (MS-DBB) neurons stimulated by NGF RGD PMID:18256260 RGD:5508750 NCBI chr10:83,389,828...83,408,061
Ensembl chr10:83,389,847...83,408,061
JBrowse link
G Tac1 tachykinin, precursor 1 IDA RGD PMID:17949415 RGD:2304335 NCBI chr 4:33,638,853...33,646,819
Ensembl chr 4:33,638,709...33,646,819
JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:17949415 RGD:2304335 NCBI chr 4:113,247,236...113,416,139
Ensembl chr 4:113,247,795...113,414,504
JBrowse link
G Uts2 urotensin 2 IDA RGD PMID:15944374 RGD:2306844 NCBI chr 5:168,078,748...168,084,133
Ensembl chr 5:168,078,748...168,084,145
JBrowse link
regulation of acetylcholine secretion, neurotransmission term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A IEA
ISO
GO_REF:0000107
MGI:MGI:1856209|MGI:MGI:2181384 (MGI:MGI:2654957|PMID:12624181), (MGI:MGI:3606714|PMID:10686170)
Ensembl
RGD
PMID:10686170, PMID:12624181 GO_REF:0000107, MGI:MGI:2654957, MGI:MGI:3606714 NCBI chr19:25,453,236...25,749,550
Ensembl chr19:25,526,751...25,749,550
JBrowse link
G Chrna3 cholinergic receptor nicotinic alpha 3 subunit ISO MGI:MGI:2155602 (MGI:MGI:3590443|PMID:16162937) RGD PMID:16162937 MGI:MGI:3590443 NCBI chr 8:59,594,007...59,607,122
Ensembl chr 8:59,592,403...59,607,275
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    regulation of biological process 13075
      regulation of signaling 3492
        regulation of trans-synaptic signaling 657
          modulation of chemical synaptic transmission 656
            regulation of synaptic transmission, cholinergic 14
              modulation by symbiont of host cholinergic synaptic transmission + 0
              negative regulation of synaptic transmission, cholinergic + 1
              positive regulation of synaptic transmission, cholinergic + 10
              regulation of acetylcholine secretion, neurotransmission + 6
Path 2
Term Annotations click to browse term
  biological_process 20027
    cellular process 18798
      cell communication 7664
        cell-cell signaling 1738
          synaptic signaling 917
            trans-synaptic signaling 889
              anterograde trans-synaptic signaling 880
                chemical synaptic transmission 880
                  modulation of chemical synaptic transmission 656
                    regulation of synaptic transmission, cholinergic 14
                      modulation by symbiont of host cholinergic synaptic transmission + 0
                      negative regulation of synaptic transmission, cholinergic + 1
                      positive regulation of synaptic transmission, cholinergic + 10
                      regulation of acetylcholine secretion, neurotransmission + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.