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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of telomere maintenance via telomerase
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Accession:GO:0032210 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.


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regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in IGI (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G POT1 protection of telomeres 1 involved_in IBA
IGI
(PMID:21873635)
(PMID:26586433)
GO_Central
BHF-UCL
PMID:21873635 PMID:26586433 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G SMG5 SMG5 nonsense mediated mRNA decay factor involved_in TAS (PMID:16507993) BHF-UCL PMID:16507993 NCBI chr 1:156,249,224...156,291,516
Ensembl chr 1:156,249,224...156,282,825
JBrowse link
G SMG6 SMG6 nonsense mediated mRNA decay factor involved_in TAS
IC
(PMID:16507993)
(PMID:22011238)
BHF-UCL PMID:16507993 PMID:22011238 NCBI chr17:2,059,839...2,303,836
Ensembl chr17:2,059,839...2,303,785
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IMP
IBA
IDA
(PMID:19864690)
(PMID:21873635)
(PMID:23685356)
BHF-UCL
GO_Central
PMID:19864690 PMID:21873635 PMID:23685356 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TNKS tankyrase involved_in IC (PMID:9822378) BHF-UCL PMID:9822378 NCBI chr 8:9,555,230...9,782,346
Ensembl chr 8:9,555,912...9,782,346
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IBA
IGI
IMP
TAS
(PMID:21873635)
(PMID:15181449)
(PMID:15380063)
(PMID:17237768), (PMID:25467444)
GO_Central
BHF-UCL
PMID:15181449 PMID:15380063 PMID:17237768 PMID:21873635 PMID:25467444 NCBI chr16:67,657,512...67,660,832
Ensembl chr16:67,657,512...67,660,815
JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in IDA (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr17:8,224,815...8,248,079
Ensembl chr17:8,224,815...8,248,056
JBrowse link
G DCP2 decapping mRNA 2 involved_in IMP (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 5:112,976,702...113,022,195
Ensembl chr 5:112,976,702...113,022,195
JBrowse link
G EXOSC10 exosome component 10 involved_in IMP (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 1:11,066,613...11,099,869
Ensembl chr 1:11,066,618...11,099,869
JBrowse link
G GNL3L G protein nucleolar 3 like involved_in IMP (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr  X:54,530,219...54,567,289
Ensembl chr  X:54,530,183...54,621,521
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in IMP (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G HNRNPC heterogeneous nuclear ribonucleoprotein C involved_in IMP (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr14:21,209,147...21,269,442
Ensembl chr14:21,209,136...21,269,494
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in IBA
IMP
(PMID:21873635)
(PMID:18082603)
GO_Central
BHF-UCL
PMID:18082603 PMID:21873635 NCBI chr 1:244,850,297...244,864,543
Ensembl chr 1:244,840,638...244,864,560
JBrowse link
G NAT10 N-acetyltransferase 10 involved_in IMP (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr11:34,105,629...34,146,908
Ensembl chr11:34,105,617...34,147,670
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in IDA (PMID:23657261) BHF-UCL PMID:23657261 NCBI chr15:64,815,632...64,827,173
Ensembl chr15:64,815,632...64,825,668
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in IDA
IMP
(PMID:11701125)
(PMID:21119197)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chr 8:10,764,961...10,839,875
Ensembl chr 8:10,725,399...10,839,847
Ensembl chr 8:10,725,399...10,839,847
JBrowse link
G PML PML nuclear body scaffold involved_in IMP (PMID:19567472) UniProt PMID:19567472 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827
JBrowse link
G POT1 protection of telomeres 1 involved_in TAS
IGI
(PMID:17237768)
(PMID:15181449)
BHF-UCL PMID:15181449 PMID:17237768 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr20:37,344,690...37,406,050
Ensembl chr20:37,344,685...37,406,050
JBrowse link
G STN1 STN1 subunit of CST complex involved_in IDA (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr10:103,877,569...103,918,184
Ensembl chr10:103,877,569...103,918,184
JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IDA
IBA
(PMID:22763445)
(PMID:21873635)
BHF-UCL
GO_Central
PMID:21873635 PMID:22763445 NCBI chr17:75,979,240...76,000,586
Ensembl chr17:75,979,240...76,000,586
JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in IMP (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr16:50,152,911...50,235,310
Ensembl chr16:50,152,911...50,235,310
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in TAS
IGI
(PMID:16275645), (PMID:24389012)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:16275645 PMID:24389012 NCBI chr 8:73,008,856...73,048,123
Ensembl chr 8:73,008,856...73,048,123
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in IDA
IC
IMP
(PMID:17055345)
(PMID:15657433)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:15657433 PMID:17055345 NCBI chr16:69,355,567...69,386,007
Ensembl chr16:69,355,567...69,408,571
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in IGI
IMP
(PMID:10581025)
(PMID:15133513)
BHF-UCL PMID:10581025 PMID:15133513 NCBI chr14:24,239,640...24,242,674
Ensembl chr14:24,239,643...24,242,674
JBrowse link
G XRN1 5'-3' exoribonuclease 1 involved_in IC (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 3:142,306,610...142,448,062
Ensembl chr 3:142,306,607...142,448,062
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in IDA (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr16:67,657,512...67,660,832
Ensembl chr16:67,657,512...67,660,815
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,223,044...108,369,102
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISS BHF-UCL GO_REF:0000024 NCBI chr 3:142,449,235...142,578,793
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G AURKB aurora kinase B involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr17:8,204,731...8,210,767
Ensembl chr17:8,204,733...8,210,600
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 1:156,308,968...156,338,292
Ensembl chr 1:156,308,968...156,367,873
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 2:61,868,085...61,888,671
Ensembl chr 2:61,868,085...61,888,671
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:56,051,765...56,063,989
Ensembl chr 7:56,051,685...56,063,989
JBrowse link
G CCT7 chaperonin containing TCP1 subunit 7 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 2:73,233,425...73,253,008
Ensembl chr 2:73,233,420...73,253,021
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr21:29,056,326...29,073,648
Ensembl chr21:29,055,805...29,073,797
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISS ARUK-UCL GO_REF:0000024 NCBI chr 3:41,199,422...41,240,445
Ensembl chr 3:41,194,741...41,260,096
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3047190|PMID:15240872) Ensembl
MGI
PMID:15240872 GO_REF:0000107 MGI:3047190 NCBI chr  X:154,762,864...154,777,689
Ensembl chr  X:154,762,742...154,777,689
JBrowse link
G FBXO4 F-box protein 4 involved_in IC
IMP
(PMID:24389012)
(PMID:16275645)
BHF-UCL PMID:16275645 PMID:24389012 NCBI chr 5:41,918,061...42,040,230
Ensembl chr 5:41,925,254...41,941,743
JBrowse link
G HMBOX1 homeobox containing 1 involved_in IMP
IDA
(PMID:23685356) BHF-UCL PMID:23685356 NCBI chr 8:28,890,394...29,064,945
Ensembl chr 8:28,890,395...29,064,764
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in IDA (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr12:54,280,726...54,287,087
Ensembl chr12:54,280,193...54,287,088
JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:7,903,785...7,914,478
Ensembl chr19:7,903,843...7,914,478
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:160,991,521...161,117,385
Ensembl chr 6:160,991,727...161,117,385
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in IDA
IMP
(PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 8:143,716,305...143,722,458
Ensembl chr 8:143,716,340...143,722,458
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr12:111,842,228...111,902,222
Ensembl chr12:111,842,228...111,902,222
JBrowse link
G NAF1 nuclear assembly factor 1 ribonucleoprotein involved_in TAS (PMID:22527283) BHF-UCL PMID:22527283 NCBI chr 4:163,109,133...163,166,910
Ensembl chr 4:163,110,073...163,166,890
JBrowse link
G NEK2 NIMA related kinase 2 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630
JBrowse link
G NEK7 NIMA related kinase 7 involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:198,156,998...198,322,420
Ensembl chr 1:198,156,994...198,322,420
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in IMP (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878 PMID:26950371 NCBI chr16:14,435,701...14,630,286
Ensembl chr16:14,435,700...14,632,728
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:122,471,921...122,726,373
Ensembl chr 6:122,471,917...122,726,373
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr19:49,861,204...49,867,576
Ensembl chr19:49,859,882...49,878,351
JBrowse link
G POT1 protection of telomeres 1 involved_in IMP
IDA
(PMID:12768206), (PMID:12781132)
(PMID:17237768)
BHF-UCL PMID:12768206 PMID:12781132 PMID:17237768 NCBI chr 7:124,822,386...124,929,825
Ensembl chr 7:124,822,386...124,929,983
JBrowse link
G PRKCQ protein kinase C theta involved_in IMP (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr10:6,393,038...6,580,646
Ensembl chr10:6,427,143...6,580,301
JBrowse link
G TCP1 t-complex 1 involved_in IMP (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703
JBrowse link
G TERC telomerase RNA component acts_upstream_of_or_within ISO (MGI:3774867|PMID:17982445) MGI PMID:17982445 MGI:3774867 NCBI chr 3:169,764,610...169,765,060
Ensembl chr 3:169,764,610...169,765,047
Ensembl chr 3:169,764,610...169,765,047
JBrowse link
G TNKS tankyrase involved_in IDA
IEA
IMP
(PMID:12782650), (PMID:18221737)
(PMID:11739745)
BHF-UCL
InterPro
PMID:11739745 PMID:12782650 PMID:18221737 GO_REF:0000002 NCBI chr 8:9,555,230...9,782,346
Ensembl chr 8:9,555,912...9,782,346
JBrowse link
G TNKS2 tankyrase 2 involved_in IC (PMID:11739745) BHF-UCL PMID:11739745 NCBI chr10:91,798,426...91,865,475
Ensembl chr10:91,798,426...91,865,475
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in IMP (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr 2:216,109,348...216,206,293
Ensembl chr 2:216,107,464...216,206,303
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      regulation of metabolic process 7180
        regulation of macromolecule metabolic process 6639
          regulation of DNA metabolic process 405
            regulation of DNA biosynthetic process 128
              regulation of telomere maintenance via telomerase 55
                negative regulation of telomere maintenance via telomerase 21
                positive regulation of telomere maintenance via telomerase 35
Path 2
Term Annotations click to browse term
  biological_process 18537
    metabolic process 11867
      cellular metabolic process 10809
        cellular aromatic compound metabolic process 6016
          nucleobase-containing compound metabolic process 5774
            nucleic acid metabolic process 5271
              DNA metabolic process 964
                DNA biosynthetic process 202
                  RNA-dependent DNA biosynthetic process 74
                    telomere maintenance via telomerase 72
                      regulation of telomere maintenance via telomerase 55
                        negative regulation of telomere maintenance via telomerase 21
                        positive regulation of telomere maintenance via telomerase 35
paths to the root