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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of telomere maintenance via telomerase
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Accession:GO:0032210 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.


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regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase involved_in ISO (PMID:26586433) BHF-UCL PMID:26586433 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G POT1 protection of telomeres 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:19864690)
(PMID:23685356)
BHF-UCL PMID:19864690 PMID:23685356 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342
JBrowse link
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:15181449)
(PMID:15380063)
BHF-UCL PMID:15181449 PMID:15380063 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639
JBrowse link
G CTC1 CST telomere replication complex component 1 involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr 5:33,033,474...33,055,004
Ensembl chr 5:33,033,596...33,055,142
JBrowse link
G DCP2 decapping mRNA 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:35,256,772...35,298,974
Ensembl chr 4:35,256,970...35,299,021
JBrowse link
G EXOSC10 exosome component 10 involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 2:84,942,801...84,964,129
Ensembl chr 2:84,942,777...84,964,130
JBrowse link
G GNL3L G protein nucleolar 3 like involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr  X:46,270,162...46,296,972
Ensembl chr  X:46,189,870...46,296,966
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891
JBrowse link
G HNRNPU heterogeneous nuclear ribonucleoprotein U involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr 7:35,832,956...35,842,898
Ensembl chr 7:35,833,988...35,843,754
JBrowse link
G LOC475399 heterogeneous nuclear ribonucleoprotein C involved_in ISO (PMID:18082603) BHF-UCL PMID:18082603 NCBI chr15:18,239,810...18,299,065 JBrowse link
G NAT10 N-acetyltransferase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:33,654,701...33,692,642
Ensembl chr18:33,655,311...33,689,923
JBrowse link
G PIF1 PIF1 5'-to-3' DNA helicase involved_in ISO (PMID:23657261) BHF-UCL PMID:23657261 NCBI chr30:29,223,507...29,232,584
Ensembl chr30:29,157,119...29,232,043
JBrowse link
G PINX1 PIN2 (TERF1) interacting telomerase inhibitor 1 involved_in ISO (PMID:21119197)
(PMID:11701125)
BHF-UCL PMID:11701125 PMID:21119197 NCBI chr25:27,090,244...27,182,377
Ensembl chr25:27,021,704...27,181,968
JBrowse link
G PML PML nuclear body scaffold involved_in ISO (PMID:19567472) UniProt PMID:19567472 NCBI chr30:37,232,337...37,278,434
Ensembl chr30:37,232,306...37,277,741
JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr24:25,982,499...26,019,748
Ensembl chr24:25,999,048...26,018,077
JBrowse link
G STN1 STN1 subunit of CST complex involved_in ISO (PMID:22763445) BHF-UCL PMID:22763445 NCBI chr28:16,203,607...16,246,468
Ensembl chr28:16,204,073...16,246,058
JBrowse link
G TEN1 TEN1 subunit of CST complex involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:4,635,192...4,658,455
Ensembl chr 9:4,635,354...4,658,252
JBrowse link
G TENT4B terminal nucleotidyltransferase 4B involved_in ISO (PMID:26950371) BHF-UCL PMID:26950371 NCBI chr 2:65,068,088...65,147,853
Ensembl chr 2:65,071,111...65,147,896
JBrowse link
G TERF1 telomeric repeat binding factor 1 involved_in ISO (PMID:11971978) BHF-UCL PMID:11971978 NCBI chr29:21,664,378...21,701,491
Ensembl chr29:21,664,186...21,700,495
JBrowse link
G TERF2 telomeric repeat binding factor 2 involved_in ISO (PMID:17055345)
(PMID:11971978)
BHF-UCL PMID:11971978 PMID:17055345 NCBI chr 5:80,278,224...80,305,315
Ensembl chr 5:80,277,505...80,306,342
JBrowse link
G TINF2 TERF1 interacting nuclear factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:4,221,183...4,223,863
Ensembl chr 8:4,221,269...4,223,512
JBrowse link
positive regulation of telomere maintenance via telomerase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACD ACD shelterin complex subunit and telomerase recruitment factor involved_in ISO (PMID:17237768) BHF-UCL PMID:17237768 NCBI chr 5:81,789,915...81,792,725
Ensembl chr 5:81,789,997...81,792,639
JBrowse link
G ATM ATM serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G ATR ATR serine/threonine kinase involved_in ISO (MGI:5705431|PMID:26586427) BHF-UCL PMID:26586427 MGI:5705431 NCBI chr23:38,131,956...38,223,888
Ensembl chr23:38,132,788...38,224,016
JBrowse link
G AURKB aurora kinase B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:33,014,098...33,028,951
Ensembl chr 5:33,014,102...33,033,948
JBrowse link
G CCT2 chaperonin containing TCP1 subunit 2 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr10:11,560,287...11,586,559
Ensembl chr10:11,560,396...11,578,433
JBrowse link
G CCT3 chaperonin containing TCP1 subunit 3 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 7:41,566,274...41,583,903
Ensembl chr 7:41,566,292...41,584,863
JBrowse link
G CCT4 chaperonin containing TCP1 subunit 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:61,859,148...61,874,030
Ensembl chr10:61,859,245...61,874,389
JBrowse link
G CCT5 chaperonin containing TCP1 subunit 5 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr34:4,035,851...4,049,131
Ensembl chr34:4,035,857...4,049,244
JBrowse link
G CCT6A chaperonin containing TCP1 subunit 6A involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr 6:546,278...556,996
Ensembl chr 6:546,307...557,001
JBrowse link
G CCT8 chaperonin containing TCP1 subunit 8 involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr31:24,061,185...24,075,002
Ensembl chr31:24,061,252...24,075,364
JBrowse link
G CTNNB1 catenin beta 1 acts_upstream_of ISO (MGI:5428344|PMID:22723415) BHF-UCL PMID:22723415 MGI:5428344 NCBI chr23:10,559,722...10,572,933
Ensembl chr23:10,559,718...10,572,927
JBrowse link
G DKC1 dyskerin pseudouridine synthase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:3047190|PMID:15240872) Ensembl
MGI
PMID:15240872 GO_REF:0000107 MGI:3047190 NCBI chr  X:122,838,787...122,850,870
Ensembl chr  X:122,838,645...122,850,884
JBrowse link
G FBXO4 F-box protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:67,620,947...67,664,862
Ensembl chr 4:67,651,275...67,664,915
JBrowse link
G HMBOX1 homeobox containing 1 involved_in ISO (PMID:23685356) BHF-UCL PMID:23685356 NCBI chr25:28,489,472...28,679,322
Ensembl chr25:28,489,506...28,679,748
JBrowse link
G HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 involved_in ISO (PMID:23935072) BHF-UCL PMID:23935072 NCBI chr27:1,013,459...1,020,083
Ensembl chr27:1,015,868...1,019,891
JBrowse link
G LOC100856782 T-complex protein 1 subunit eta involved_in ISO (PMID:25467444) BHF-UCL PMID:25467444 NCBI chr34:37,026,053...37,027,839 JBrowse link
G MAP2K7 mitogen-activated protein kinase kinase 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:52,594,450...52,604,236
Ensembl chr20:52,594,536...52,602,150
JBrowse link
G MAP3K4 mitogen-activated protein kinase kinase kinase 4 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:49,590,615...49,702,289
Ensembl chr 1:49,548,274...49,702,289
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:31,013,607...31,132,998
Ensembl chr26:31,013,607...31,132,998
JBrowse link
G MAPK15 mitogen-activated protein kinase 15 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr13:37,317,061...37,322,792
Ensembl chr13:37,316,424...37,322,792
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 6:18,109,184...18,115,728
Ensembl chr 6:18,109,222...18,114,425
JBrowse link
G MAPKAPK5 MAPK activated protein kinase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:9,380,551...9,420,564
Ensembl chr26:9,319,180...9,419,236
JBrowse link
G NEK2 NIMA related kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:10,039,617...10,052,511
Ensembl chr 7:10,040,187...10,052,512
JBrowse link
G NEK7 NIMA related kinase 7 involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 7:4,557,754...4,755,912
Ensembl chr 7:4,555,231...4,704,955
JBrowse link
G PARN poly(A)-specific ribonuclease involved_in ISO (PMID:26482878), (PMID:26950371) BHF-UCL PMID:26482878 PMID:26950371 NCBI chr 6:28,629,137...28,783,671
Ensembl chr 6:28,629,174...28,783,901
JBrowse link
G PKIB cAMP-dependent protein kinase inhibitor beta involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:61,960,466...62,049,553
Ensembl chr 1:61,967,129...62,088,547
JBrowse link
G PNKP polynucleotide kinase 3'-phosphatase involved_in ISO (PMID:21531765) BHF-UCL PMID:21531765 NCBI chr 1:106,695,649...106,707,229
Ensembl chr 1:106,694,589...106,702,150
JBrowse link
G POT1 protection of telomeres 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:10,987,385...11,067,473
Ensembl chr14:10,987,494...11,066,956
JBrowse link
G PRKCQ protein kinase C theta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:29,319,123...29,505,338
Ensembl chr 2:29,318,870...29,505,337
JBrowse link
G TCP1 t-complex 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:49,029,260...49,038,023
Ensembl chr 1:49,029,282...49,038,020
JBrowse link
G TNKS tankyrase involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:34,826,248...35,040,004
Ensembl chr16:34,831,662...35,039,946
JBrowse link
G XRCC5 X-ray repair cross complementing 5 involved_in ISO (PMID:19188702) BHF-UCL PMID:19188702 NCBI chr37:23,095,769...23,185,680
Ensembl chr37:23,095,754...23,185,586
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      regulation of metabolic process 5649
        regulation of macromolecule metabolic process 5204
          regulation of DNA metabolic process 365
            regulation of DNA biosynthetic process 121
              regulation of telomere maintenance via telomerase 49
                negative regulation of telomere maintenance via telomerase 20
                positive regulation of telomere maintenance via telomerase 32
Path 2
Term Annotations click to browse term
  biological_process 13863
    metabolic process 8966
      cellular metabolic process 8165
        cellular aromatic compound metabolic process 4383
          nucleobase-containing compound metabolic process 4193
            nucleic acid metabolic process 3834
              DNA metabolic process 737
                DNA biosynthetic process 166
                  RNA-dependent DNA biosynthetic process 61
                    telomere maintenance via telomerase 61
                      regulation of telomere maintenance via telomerase 49
                        negative regulation of telomere maintenance via telomerase 20
                        positive regulation of telomere maintenance via telomerase 32
paths to the root